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Volumn 289, Issue 30, 2014, Pages 20570-20582

The retinal pigment epithelium utilizes fatty acids for ketogenesis implications for metabolic coupling with the outer retina

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELLS; METABOLISM; SATURATED FATTY ACIDS; VISION;

EID: 84905376420     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.565457     Document Type: Article
Times cited : (122)

References (40)
  • 1
    • 76349103967 scopus 로고    scopus 로고
    • Phagocytosis of retinal rod and cone photoreceptors
    • Kevany, B. M., and Palczewski, K. (2010) Phagocytosis of retinal rod and cone photoreceptors. Physiology 25, 8-15
    • (2010) Physiology , vol.25 , pp. 8-15
    • Kevany, B.M.1    Palczewski, K.2
  • 2
    • 0031472117 scopus 로고    scopus 로고
    • Cell membrane lipid composition and distribution: Implications for cell function and lessons learned from photoreceptors and platelets
    • Boesze-Battaglia, K., and Schimmel, R. (1997) Cell membrane lipid composition and distribution: implications for cell function and lessons learned from photoreceptors and platelets. J. Exp. Biol. 200, 2927-2936
    • (1997) J. Exp. Biol. , vol.200 , pp. 2927-2936
    • Boesze-Battaglia, K.1    Schimmel, R.2
  • 3
    • 0027525680 scopus 로고
    • Metabolism in frog retinal pigment epithelium of docosahexaenoic and arachidonic acids derived from rod outer segment membranes
    • Chen, H., and Anderson, R. E. (1993) Metabolism in frog retinal pigment epithelium of docosahexaenoic and arachidonic acids derived from rod outer segment membranes. Exp. Eye Res. 57, 369-377
    • (1993) Exp. Eye Res. , vol.57 , pp. 369-377
    • Chen, H.1    Anderson, R.E.2
  • 4
    • 0027365680 scopus 로고
    • Differential incorporation of docosahexaenoic and arachidonic acids in frog retinal pigment epithelium
    • Chen, H., and Anderson, R. E. (1993) Differential incorporation of docosahexaenoic and arachidonic acids in frog retinal pigment epithelium. J. Lipid Res. 34, 1943-1955
    • (1993) J. Lipid Res. , vol.34 , pp. 1943-1955
    • Chen, H.1    Anderson, R.E.2
  • 8
    • 0033559336 scopus 로고    scopus 로고
    • Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase: A control enzyme in ketogenesis
    • Hegardt, F. G. (1999) Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase: a control enzyme in ketogenesis. Biochem. J. 338, 569-582
    • (1999) Biochem. J. , vol.338 , pp. 569-582
    • Hegardt, F.G.1
  • 9
    • 79957992155 scopus 로고    scopus 로고
    • Human HMGCS2 regulates mitochondrial fatty acid oxidation and FGF21 expression in HepG2 cell line
    • Vilà-Brau, A., De Sousa-Coelho, A. L., Mayordomo, C., Haro, D., and Marrero, P. F. (2011) Human HMGCS2 regulates mitochondrial fatty acid oxidation and FGF21 expression in HepG2 cell line. J. Biol. Chem. 286, 20423-20430
    • (2011) J. Biol. Chem. , vol.286 , pp. 20423-20430
    • Vilà-Brau, A.1    De Sousa-Coelho, A.L.2    Mayordomo, C.3    Haro, D.4    Marrero, P.F.5
  • 10
    • 0028276397 scopus 로고
    • Peroxisome proliferator-activated receptor mediates induction of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene by fatty acids
    • Rodríguez, J. C., Gil-Gómez, G., Hegardt, F. G., and Haro, D. (1994) Peroxisome proliferator-activated receptor mediates induction of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene by fatty acids. J. Biol. Chem. 269, 18767-18772
    • (1994) J. Biol. Chem. , vol.269 , pp. 18767-18772
    • Rodríguez, J.C.1    Gil-Gómez, G.2    Hegardt, F.G.3    Haro, D.4
  • 11
    • 0034194277 scopus 로고    scopus 로고
    • Photoreceptor phagocytosis selectively activates PPARα expression in retinal pigment epithelial cells
    • Ershov, A. V., and Bazan, N. G. (2000) Photoreceptor phagocytosis selectively activates PPARα expression in retinal pigment epithelial cells. J. Neurosci. Res. 60, 328-337
    • (2000) J. Neurosci. Res. , vol.60 , pp. 328-337
    • Ershov, A.V.1    Bazan, N.G.2
  • 12
    • 84863402082 scopus 로고    scopus 로고
    • A monocarboxylate transporter required for hepatocyte secretion of ketone bodies during fasting
    • Hugo, S. E., Cruz-Garcia, L., Karanth, S., Anderson, R. M., Stainier, D. Y., and Schlegel, A. (2012) A monocarboxylate transporter required for hepatocyte secretion of ketone bodies during fasting. Genes Dev. 26, 282-293
    • (2012) Genes Dev. , vol.26 , pp. 282-293
    • Hugo, S.E.1    Cruz-Garcia, L.2    Karanth, S.3    Anderson, R.M.4    Stainier, D.Y.5    Schlegel, A.6
  • 14
    • 0032518981 scopus 로고    scopus 로고
    • Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient past
    • Price, N. T., Jackson, V. N., and Halestrap, A. P. (1998) Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient past. Biochem. J. 329, 321-328
    • (1998) Biochem. J. , vol.329 , pp. 321-328
    • Price, N.T.1    Jackson, V.N.2    Halestrap, A.P.3
  • 15
    • 1242340302 scopus 로고    scopus 로고
    • The SLC16 gene family: From monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond
    • Halestrap, A. P., and Meredith, D. (2004) The SLC16 gene family: from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. Pflugers Arch. 447, 619-628
    • (2004) Pflugers Arch. , vol.447 , pp. 619-628
    • Halestrap, A.P.1    Meredith, D.2
  • 16
    • 0037337631 scopus 로고    scopus 로고
    • Loss of MCT1, MCT3, and MCT4 expression in the retinal pigment epithelium and neural retina of the 5A11/basigin-null mouse
    • Philp, N. J., Ochrietor, J. D., Rudoy, C., Muramatsu, T., and Linser, P. J. (2003) Loss of MCT1, MCT3, and MCT4 expression in the retinal pigment epithelium and neural retina of the 5A11/basigin-null mouse. Invest. Ophthalmol. Vis. Sci. 44, 1305-1311
    • (2003) Invest. Ophthalmol. Vis. Sci. , vol.44 , pp. 1305-1311
    • Philp, N.J.1    Ochrietor, J.D.2    Rudoy, C.3    Muramatsu, T.4    Linser, P.J.5
  • 21
    • 74349094033 scopus 로고    scopus 로고
    • AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10
    • Ovens, M. J., Davies, A. J., Wilson, M. C., Murray, C. M., and Halestrap, A. P. (2010) AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10. Biochem. J. 425, 523-530
    • (2010) Biochem. J. , vol.425 , pp. 523-530
    • Ovens, M.J.1    Davies, A.J.2    Wilson, M.C.3    Murray, C.M.4    Halestrap, A.P.5
  • 22
    • 0034525940 scopus 로고    scopus 로고
    • Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle
    • Manning Fox, J. E., Meredith, D., and Halestrap, A. P. (2000) Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle. J. Physiol. 529, 285-293
    • (2000) J. Physiol. , vol.529 , pp. 285-293
    • Manning Fox, J.E.1    Meredith, D.2    Halestrap, A.P.3
  • 27
    • 6344235193 scopus 로고    scopus 로고
    • Mitochondrial fatty acid β-oxidation in the human eye and brain: Implications for the retinopathy of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency
    • Tyni, T., Paetau, A., Strauss, A. W., Middleton, B., and Kivelä, T. (2004) Mitochondrial fatty acid β-oxidation in the human eye and brain: implications for the retinopathy of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency. Pediatr. Res. 56, 744-750
    • (2004) Pediatr. Res. , vol.56 , pp. 744-750
    • Tyni, T.1    Paetau, A.2    Strauss, A.W.3    Middleton, B.4    Kivelä, T.5
  • 28
    • 0035346949 scopus 로고    scopus 로고
    • Is there an astrocyte-neuron ketone body shuttle?
    • Guzmán, M., and Blázquez, C. (2001) Is there an astrocyte-neuron ketone body shuttle? Trends Endocrinol. Metab. 12, 169-173
    • (2001) Trends Endocrinol. Metab. , vol.12 , pp. 169-173
    • Guzmán, M.1    Blázquez, C.2
  • 29
    • 0023470792 scopus 로고
    • Capacity for substrate utilization in oxidative metabolism by neurons, astrocytes, and oligodendrocytes from developing brain in primary culture
    • Edmond, J., Robbins, R. A., Bergstrom, J. D., Cole, R. A., and de Vellis, J. (1987) Capacity for substrate utilization in oxidative metabolism by neurons, astrocytes, and oligodendrocytes from developing brain in primary culture. J. Neurosci. Res. 18, 551-561
    • (1987) J. Neurosci. Res. , vol.18 , pp. 551-561
    • Edmond, J.1    Robbins, R.A.2    Bergstrom, J.D.3    Cole, R.A.4    De Vellis, J.5
  • 30
    • 0031714313 scopus 로고    scopus 로고
    • Role of carnitine palmitoyltransferase I in the control of ketogenesis in primary cultures of rat astrocytes
    • Blázquez, C., Sánchez, C., Velasco, G., and Guzmán, M. (1998) Role of carnitine palmitoyltransferase I in the control of ketogenesis in primary cultures of rat astrocytes. J. Neurochem. 71, 1597-1606
    • (1998) J. Neurochem. , vol.71 , pp. 1597-1606
    • Blázquez, C.1    Sánchez, C.2    Velasco, G.3    Guzmán, M.4
  • 31
    • 84887087876 scopus 로고    scopus 로고
    • Photoreceptor phagocytosis is mediated by phosphoinositide signaling
    • Mustafi, D., Kevany, B. M., Genoud, C., Bai, X., and Palczewski, K. (2013) Photoreceptor phagocytosis is mediated by phosphoinositide signaling. FASEB J. 27, 4585-4595
    • (2013) FASEB J. , vol.27 , pp. 4585-4595
    • Mustafi, D.1    Kevany, B.M.2    Genoud, C.3    Bai, X.4    Palczewski, K.5
  • 32
    • 0032212151 scopus 로고    scopus 로고
    • The major cell populations of the mouse retina
    • Jeon, C. J., Strettoi, E., and Masland, R. H. (1998) The major cell populations of the mouse retina. J. Neurosci. 18, 8936-8946
    • (1998) J. Neurosci. , vol.18 , pp. 8936-8946
    • Jeon, C.J.1    Strettoi, E.2    Masland, R.H.3
  • 33
    • 44449139646 scopus 로고    scopus 로고
    • The locations of mitochondria in mammalian photoreceptors: Relation to retinal vasculature
    • Stone, J., van Driel, D., Valter, K., Rees, S., and Provis, J. (2008) The locations of mitochondria in mammalian photoreceptors: relation to retinal vasculature. Brain Res. 1189, 58-69
    • (2008) Brain Res. , vol.1189 , pp. 58-69
    • Stone, J.1    Van Driel, D.2    Valter, K.3    Rees, S.4    Provis, J.5
  • 34
    • 0029009496 scopus 로고
    • Lactate released by Muller glial cells is metabolized by photoreceptors from mammalian retina
    • Poitry-Yamate, C. L., Poitry, S., and Tsacopoulos, M. (1995) Lactate released by Muller glial cells is metabolized by photoreceptors from mammalian retina. J. Neurosci. 15, 5179-5191
    • (1995) J. Neurosci. , vol.15 , pp. 5179-5191
    • Poitry-Yamate, C.L.1    Poitry, S.2    Tsacopoulos, M.3
  • 38
    • 84890978770 scopus 로고    scopus 로고
    • Ketone bodies as signaling metabolites
    • Newman, J. C., and Verdin, E. (2014) Ketone bodies as signaling metabolites. Trends Endocrinol. Metab. 25, 42-52
    • (2014) Trends Endocrinol. Metab. , vol.25 , pp. 42-52
    • Newman, J.C.1    Verdin, E.2
  • 40
    • 0028272971 scopus 로고
    • Retinal photoreceptor count, retinal surface area, and optic disc size in normal human eyes
    • Panda-Jonas, S., Jonas, J. B., Jakobczyk, M., and Schneider, U. (1994) Retinal photoreceptor count, retinal surface area, and optic disc size in normal human eyes. Ophthalmology 101, 519-523
    • (1994) Ophthalmology , vol.101 , pp. 519-523
    • Panda-Jonas, S.1    Jonas, J.B.2    Jakobczyk, M.3    Schneider, U.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.