All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins

Nature Methods

Volumn 11, Issue 8, 2014, Pages 825-833

  Hochbaum, Daniel R ^a   Zhao, Yongxin ^b   Farhi, Samouil L ^c   Klapoetke, Nathan ^d,e,f,g   Werley, Christopher A ^c   Kapoor, Vikrant ^h   Zou, Peng ^c   Kralj, Joel M ^c   MacLaurin, Dougal ^a   Smedemark Margulies, Niklas ^c   Saulnier, Jessica L ⁱ   Boulting, Gabriella L ⁱ   Straub, Christoph ⁱ   Cho, Yong Ku ^d,e,f,g   Melkonian, Michael ^j   Wong, Gane Ka Shu ^b,k   Harrison, D Jed ^b   Murthy, Venkatesh N ^h   Sabatini, Bernardo L ^h,i   Boyden, Edward S ^d,e,f,g   Campbell, Robert E ^b   Cohen, Adam E ^a,c,h   more..

^a HARVARD UNIVERSITY   (United States)

^b UNIVERSITY OF ALBERTA   (Canada)

^c HARVARD UNIVERSITY   (United States)

^d MIT MEDIA LAB   (United States)

^e Massachusetts Institute of Technology Cambridge   (United States)

^f MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^g MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^h HARVARD UNIVERSITY   (United States)

ⁱ HARVARD MEDICAL SCHOOL   (United States)

^j UNIVERSITY OF COLOGNE   (Germany)

^k BGI SHENZHEN   (China)

more..

Author keywords

[No Author keywords available]

Indexed keywords

RHODOPSIN;

ACTION POTENTIAL; ALL OPTICAL ELECTROPHYSIOLOGY; ANIMAL CELL; ARTICLE; DENDRITIC SPINE; ELECTROPHYSIOLOGY; NERVE CELL; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; RAT; SYNAPTIC TRANSMISSION;

ANIMALS; DIRECTED MOLECULAR EVOLUTION; MAMMALS; NEURONS; RECOMBINANT PROTEINS; RHODOPSIN; SYNAPTIC TRANSMISSION;

EID: 84905281576     PISSN: 15487091     EISSN: 15487105     Source Type: Journal    
DOI: 10.1038/NMETH.3000     Document Type: Article

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