Dihydroisoxazole inhibitors of Anopheles gambiae seminal transglutaminase AgTG3

Malaria Journal

Volumn 13, Issue 1, 2014, Pages

  Le, Binh V ^a   Klöck, Cornelius ^b   Schatz, Alexandra ^a   Nguyen, Jennifer B ^a   Kakani, Evdoxia G ^c,d   Catteruccia, Flaminia ^c,d   Khosla, Chaitan ^b   Baxter, Richard H G ^a  

^a YALE UNIVERSITY   (United States)

^b STANFORD UNIVERSITY   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d UNIVERSITY OF PERUGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOSTERILANT; CROSS LINKING REAGENT; CYSTEINE PROTEINASE INHIBITOR; INSECT PROTEIN; ISOXAZOLE DERIVATIVE; MOLECULAR LIBRARY; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; RECOMBINANT PROTEIN; TGM3 PROTEIN, HUMAN;

ANIMAL; ANOPHELES GAMBIAE; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECTS; DRUG SCREENING; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYMOLOGY; FEMALE; HUMAN; IC50; MALE; MOLECULAR LIBRARY; MOSQUITO; PROCEDURES; PROTEIN CONFORMATION; SPECIES DIFFERENCE; SPERM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; ANOPHELES GAMBIAE; CATALYTIC DOMAIN; CHEMOSTERILANTS; CROSS-LINKING REAGENTS; CYSTEINE PROTEINASE INHIBITORS; DRUG EVALUATION, PRECLINICAL; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; INSECT PROTEINS; ISOXAZOLES; MALE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MOSQUITO CONTROL; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SEMEN; SMALL MOLECULE LIBRARIES; SPECIES SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; TRANSGLUTAMINASES;

EID: 84905259402     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-13-210     Document Type: Article

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