Kinetic analysis of the interaction of tissue transglutaminase with a nonpeptidic slow-binding inhibitor

Biochemistry

Volumn 46, Issue 4, 2007, Pages 1106-1115

  Case, April ^a   Stein, Ross L ^a  

^a The Harvard Center for Neurodegeneration & Repair   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTRACELLULAR PROTEINS; MULTIPLE CONFORMATIONAL STATES; NEURODEGENERATIVE DISEASES; THERAPEUTIC AGENTS; TISSUE TRANSGLUTAMINASE (TGASE);

CATALYSIS; CONFORMATIONS; CROSSLINKING; DISEASES; ENZYME INHIBITION; ENZYME KINETICS; TISSUE;

ENZYMES;

LDN 27219; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE ANTIBODY; TISSUE TRANSGLUTAMINASE; TISSUE TRANSGLUTAMINASE INHIBITOR; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; CATALYSIS; DEGENERATIVE DISEASE; DRUG MECHANISM; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME KINETICS; INHIBITION KINETICS; INTRACELLULAR TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING;

ANIMALS; BINDING SITES; CALCIUM; ENZYME ACTIVATION; ENZYME INHIBITORS; GUANOSINE TRIPHOSPHATE; GUINEA PIGS; HUMANS; KINETICS; MODELS, BIOLOGICAL; TRANSGLUTAMINASES;

EID: 33846601817     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi061787u     Document Type: Article

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