Mesenchymal stem cells ameliorate rhabdomyolysis-induced acute kidney injury via the activation of M2 macrophages

Stem Cell Research and Therapy

Volumn 5, Issue 3, 2014, Pages

  Geng, Yanqiu ^a,b   Zhang, Li ^a   Fu, Bo ^a   Zhang, Jianrong ^b   Hong, Quan ^a   Hu, Jie ^a   Li, Diangeng ^a   Luo, Congjuan ^a   Cui, Shaoyuan ^a   Zhu, Fei ^a   Chen, Xiangmei ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b GENERAL HOSPITAL OF CHINESE PEOPLE'S ARMED POLICE FORCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE KIDNEY INJURY; ANIMAL; C57BL MOUSE; COMPLICATION; CONFOCAL MICROSCOPY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOLOGY; MACROPHAGE; MACROPHAGE ACTIVATION; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMA CELL; MOUSE; PROCEDURES; REAL TIME POLYMERASE CHAIN REACTION; RHABDOMYOLYSIS; WESTERN BLOTTING;

ACUTE KIDNEY INJURY; ANIMALS; BLOTTING, WESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; REAL-TIME POLYMERASE CHAIN REACTION; RHABDOMYOLYSIS;

EID: 84905221047     PISSN: None     EISSN: 17576512     Source Type: Journal    
DOI: 10.1186/scrt469     Document Type: Article

References (36)

1. Rhabdomyolysis. Bagley WH, Yang H, Shah KH, Intern Emerg Med 2007 2 210 218
2. Rhabdomyolysis and acute kidney injury. Bosch X, Poch E, Grau JM, N Engl J Med 2009 361 62 72
3. The clinical features and outcome of crush patients with acute kidney injury after the Wenchuan earthquake: differences between elderly and younger adults. Zhang L, Fu P, Wang L, Cai GY, Zhang L, Chen DZ, Guo DY, Sun XF, Chen FQ, Bi WH, Zeng XJ, Li HY, Liu ZH, Wang Y, Huang SM, Chen XM, Injury 2012 43 1470 1475
4. Experimental models of acute tubular necrosis. Tanner GA, CRC Handbook of Animal Models of Renal Failure Thornhill. Boca Raton, FL: CRC Press 1985 109 144
5. Glomerular hemodynamics in established glycerol-induced acute renal failure in the rat. Wolfert AI, Oken DE, J Clin Invest 1989 84 1967 1973 (Pubitemid 20016205)
6. Role of caspases on cell death, inflammation, and cell cycle in glycerol-induced acute renal failure. Homsi E, Janino P, de Faria JB, Kidney Int 2006 69 1385 1392
7. Paracrine mechanisms of mesenchymal stem cell-based therapy: current status and perspectives. Liang X, Ding Y, Zhang Y, Tse HF, Lian Q, Cell Transplant in press
8. Mesenchymal stem cell-based therapy. Mundra V, Gerling IC, Mahato RI, Mol Pharm 2013 10 77 89
9. Stem cells derived from human amniotic fluid contribute to acute kidney injury recovery. Hauser PV, De Fazio R, Bruno S, Sdei S, Grange C, Bussolati B, Benedetto C, Camussi G, Am J Pathol 2010 177 2011 2021
10. Mesenchymal stem cells contribute to the renal repair of acute tubular epithelial injury. Herrera MB, Bussolati B, Bruno S, Fonsato V, Romanazzi GM, Camussi G, Int J Mol Med 2004 14 1035 1041
11. Exogenous mesenchymal stem cells localize to the kidney by means of CD44 following acute tubular injury. Herrera MB, Bussolati B, Bruno S, Morando L, Mauriello-Romanazzi G, Sanavio F, Stamenkovic I, Biancone L, Camussi G, Kidney Int 2007 72 430 441 (Pubitemid 47237610)
12. Macrophage Wnt7b is critical for kidney repair and regeneration. Lin SL, Li B, Rao S, Yeo EJ, Hudson TE, Nowlin BT, Pei HY, Chen L, Zheng JJ, Carroll TJ, Pollard JW, McMahon AP, Lang RA, Duffield JS, Proc Natl Acad Sci U S A 2010 107 4194 4199
13. The role of macrophages in glomerulonephritis. Nikolic-Paterson DJ, Atkins RC, Nephrol Dial Transplant 2001 16 3 S7
14. Do macrophages kill through apoptosis? Aliprantis AO, Diez-Roux G, Mulder LC, Zychlinsky A, Lang RA, Immunol Today 1996 17 573 576 (Pubitemid 26423422)
15. Macrophages in immune renal injury. Nikolic-Paterson DJLH, Atkins RC, Immunologic Renal Disease Philadelphia: Lippincott, Williams & Wilkins, Neilson EG, Couser W, 2 2001 609 632
16. Mesenchymal stem cells in acute kidney injury. Humphreys BD, Bonventre JV, Annu Rev Med 2008 59 311 325 (Pubitemid 351287940)
17. CSF-1 signals directly to renal tubular epithelial cells to mediate repair in mice. Menke J, Iwata Y, Rabacal WA, Basu R, Yeung YG, Humphreys BD, Wada T, Schwarting A, Stanley ER, Kelley VR, J Clin Invest 2009 119 2330 2342
18. + cells impairs the recovery process in ischaemia/reperfusion-induced acute kidney injury. Kim MG, Boo CS, Ko YS, Lee HY, Cho WY, Kim HK, Jo SK, Nephrol Dial Transplant 2010 25 2908 2921
19. Distinct macrophage phenotypes contribute to kidney injury and repair. Lee S, Huen S, Nishio H, Nishio S, Lee HK, Choi BS, Ruhrberg C, Cantley LG, J Am Soc Nephrol 2011 22 317 326
20. Impaired IL-18 processing protects caspase-1-deficient mice from ischemic acute renal failure. Melnikov VY, Ecder T, Fantuzzi G, Sieqmund B, Lucia MS, Dinarello CA, Schrier RW, Edelstein CL, J Clin Invest 2001 107 1145 1152 (Pubitemid 32422911)
21. Mesenchymal stem cells protect podocytes from apoptosis induced by high glucose via secretion of epithelial growth factor. Li DG, Wang N, Zhang L, Zhu HY, Bai XY, Fu B, Cui SY, Zhang WG, Sun XF, Li RS, Chen XM, Stem Cell Res Ther 2013 4 103
22. Calcium-binding proteins annexin A2 and S100A6 are sensors of tubular injury and recovery in acute renal failure. Cheng CW, Rifai A, Ka SM, Shui HA, Lin YF, Lee WH, Chen A, Kidney Int 2005 68 2694 2703 (Pubitemid 43251014)
23. Mesenchymal stem cell-educated macrophages: A novel type of alternatively activated macrophages. Kim J, Hematti P, Exp Hematol 2009 37 1445 1453
24. Ex vivo programmed macrophages ameliorate experimental chronic inflammatory renal disease. Wang Y, Wang YP, Zheng G, Lee VW, Ouyang L, Chang DH, Mahajan D, Coombs J, Wang YM, Alexander SI, Harris DC, Kidney Int 2007 72 290 299 (Pubitemid 47172367)
25. Single cell analyses of cytokine production. Carter LL, Swain SL, Curr Opin Immunol 1997 9 177 182 (Pubitemid 27190115)
26. Intracytoplasmic detection of proinflammatory cytokines and chemokines in monocytes by flow cytometry. Schultz C, Methods Mol Biol 2003 215 29 39
27. Pathogenetic mechanisms in experimental hemoglobinuric acute renal failure. Zager RA, Gamelin LM, Am J Physiol 1989 256 446 F455
28. Recent advances in the pathophysiology of ischemic acute renal failure. Bonventre JV, Weinberg JM, J Am Soc Nephrol 2003 14 2199 2210 (Pubitemid 36909930)
29. Mesenchymal stem cells are renotropic, helping to repair the kidney and improve function in acute renal failure. Morigi M, Imberti B, Zoja C, Corna D, Tomasoni S, Abbate M, Rottoli D, Angioletti S, Benigni A, Perico N, Alison M, Remuzzi G, J Am Soc Nephrol 2004 15 1794 1804 (Pubitemid 38822058)
30. Insulin-like growth factor-1 sustains stem cell-mediated renal repair. Imberti B, Morigi M, Tomasoni S, Rota C, Corna D, Longaretti L, Rottoli D, Valsecchi F, Benigni A, Wang J, Abbate M, Zoja C, Remuzzi G, J Am Soc Nephrol 2007 18 2921 2928 (Pubitemid 350058399)
31. Mesenchymal stem cells attenuate ischemic acute kidney injury by inducing regulatory T cells through splenocyte interactions. Hu J, Zhang L, Wang N, Ding R, Cui SY, Zhu F, Xie YS, Sun XF, Wu D, Hong Q, Li QG, Shi SZ, Liu XL, Chen XM, Kidney Int 2013 84 521 531
32. Human bone marrow mesenchymal stem cells accelerate recovery of acute renal injury and prolong survival in mice. Morigi M, Introna M, Imberti B, Corna D, Abbate M, Rota C, Rottoli D, Benigni A, Perico N, Zoja C, Rambaldi A, Remuzzi A, Remuzzi G, Stem Cells 2008 26 2075 2082
33. Alternative activation of macrophages. Gordon S, Nat Rev Immunol 2003 3 23 35 (Pubitemid 37328697)
34. Macrophage diversity in renal injury and repair. Ricardo SD, van Goor H, Eddy AA, J Clin Invest 2008 118 3522 3530
35. Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. Stein M, Keshav S, Harris N, Gordon S, J Exp Med 1992 176 287 292
36. Human gingiva-derived mesenchymal stem cells elicit polarization of M2 macrophages and enhance cutaneous wound healing. Zhang QZ, Su WR, Shi SH, Wilder-Smith P, Xiang AP, Wong A, Nguyen AL, Kwon CW, Le AD, Stem Cells 2010 28 1856 1868