메뉴 건너뛰기




Volumn 84, Issue 3, 2013, Pages 521-531

Mesenchymal stem cells attenuate ischemic acute kidney injury by inducing regulatory T cells through splenocyte interactions

Author keywords

ischemic acute kidney injury; mesenchymal stem cells; regulatory T cells; spleen

Indexed keywords

ANTIBODY; CREATININE; GAMMA INTERFERON;

EID: 84883455679     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2013.114     Document Type: Article
Times cited : (103)

References (49)
  • 1
    • 34247207875 scopus 로고    scopus 로고
    • Epidemiology of acute renal failure: The tip of the iceberg
    • Palevsky PM. Epidemiology of acute renal failure: The tip of the iceberg. Clin J Am Soc Nephrol 2006; 1: 6-7.
    • (2006) Clin J Am Soc Nephrol , vol.1 , pp. 6-7
    • Palevsky, P.M.1
  • 2
    • 65349174487 scopus 로고    scopus 로고
    • Autologous and allogeneic marrow stromal cells are safe and effective for the treatment of acute kidney injury
    • Togel F, Cohen A, Zhang P et al. Autologous and allogeneic marrow stromal cells are safe and effective for the treatment of acute kidney injury. Stem Cells Dev 2009; 18: 475-485.
    • (2009) Stem Cells Dev , vol.18 , pp. 475-485
    • Togel, F.1    Cohen, A.2    Zhang, P.3
  • 3
    • 65349189919 scopus 로고    scopus 로고
    • Early modulation of inflammation by mesenchymal stem cell after acute kidney injury
    • Semedo P, Palasio CG, Oliveira CD et al. Early modulation of inflammation by mesenchymal stem cell after acute kidney injury. Int Immunopharmacol 2009; 9: 677-682.
    • (2009) Int Immunopharmacol , vol.9 , pp. 677-682
    • Semedo, P.1    Palasio, C.G.2    Oliveira, C.D.3
  • 4
    • 79952987665 scopus 로고    scopus 로고
    • Mesenchymal stem cells ameliorate ischemiareperfusion-induced renal dysfunction by improving the antioxidant/ oxidant balance in the ischemic kidney
    • Zhuo W, Liao L, Xu T et al. Mesenchymal stem cells ameliorate ischemiareperfusion-induced renal dysfunction by improving the antioxidant/ oxidant balance in the ischemic kidney. Urol Int 2011; 86: 191-196.
    • (2011) Urol Int , vol.86 , pp. 191-196
    • Zhuo, W.1    Liao, L.2    Xu, T.3
  • 5
    • 72849107259 scopus 로고    scopus 로고
    • Immune mechanisms and novel pharmacological therapies of acute kidney injury
    • Bajwa A, Kinsey GR, Okusa MD. Immune mechanisms and novel pharmacological therapies of acute kidney injury. Curr Drug Targets 2009; 10: 1196-1204.
    • (2009) Curr Drug Targets , vol.10 , pp. 1196-1204
    • Bajwa, A.1    Kinsey, G.R.2    Okusa, M.D.3
  • 6
    • 30944469853 scopus 로고    scopus 로고
    • Inflammation and caspase activation in long-term renal ischemia/reperfusion injury and immunosuppression in rats
    • Yang B, Jain S, Pawluczyk IZ et al. Inflammation and caspase activation in long-term renal ischemia/reperfusion injury and immunosuppression in rats. Kidney Int 2005; 68: 2050-2067.
    • (2005) Kidney Int , vol.68 , pp. 2050-2067
    • Yang, B.1    Jain, S.2    Pawluczyk, I.Z.3
  • 7
    • 0041828955 scopus 로고    scopus 로고
    • Effect of immunosuppression on damage, leukocyte infiltration, and regeneration after severe warm ischemia/reperfusion renal injury
    • Ysebaert DK, De Greef KE, Vercauteren SR et al. Effect of immunosuppression on damage, leukocyte infiltration, and regeneration after severe warm ischemia/reperfusion renal injury. Kidney Int 2003; 64: 864-873.
    • (2003) Kidney Int , vol.64 , pp. 864-873
    • Ysebaert, D.K.1    De Greef, K.E.2    Vercauteren, S.R.3
  • 8
    • 0034796763 scopus 로고    scopus 로고
    • Anti-B7-1 blocks mononuclear cell adherence in vasa recta after ischemia
    • De Greef KE, Ysebaert DK, Dauwe S et al. Anti-B7-1 blocks mononuclear cell adherence in vasa recta after ischemia. Kidney Int 2001; 60: 1415-1427.
    • (2001) Kidney Int , vol.60 , pp. 1415-1427
    • De Greef, K.E.1    Ysebaert, D.K.2    Dauwe, S.3
  • 9
    • 0037183935 scopus 로고    scopus 로고
    • Protective effect of T cell depletion in murine renal ischemia-reperfusion injury
    • Yokota N, Daniels F, Crosson J et al. Protective effect of T cell depletion in murine renal ischemia-reperfusion injury. Transplantation 2002; 74: 759-763.
    • (2002) Transplantation , vol.74 , pp. 759-763
    • Yokota, N.1    Daniels, F.2    Crosson, J.3
  • 10
    • 0035193573 scopus 로고    scopus 로고
    • Identification of the CD4(+) T cell as a major pathogenic factor in ischemic acute renal failure
    • Burne MJ, Daniels F, El Ghandour A et al. Identification of the CD4(+) T cell as a major pathogenic factor in ischemic acute renal failure. J Clin Invest 2001; 108: 1283-1290.
    • (2001) J Clin Invest , vol.108 , pp. 1283-1290
    • Burne, M.J.1    Daniels, F.2    El Ghandour, A.3
  • 11
    • 33747796268 scopus 로고    scopus 로고
    • Phenotypic and functional characterization of kidney-infiltrating lymphocytes in renal ischemia reperfusion injury.
    • Ascon DB, Lopez-Briones S, Liu M et al. Phenotypic and functional characterization of kidney-infiltrating lymphocytes in renal ischemia reperfusion injury. J Immunol 2006; 177: 3380-3387.
    • (2006) J Immunol , vol.177 , pp. 3380-3387
    • Ascon, D.B.1    Lopez-Briones, S.2    Liu, M.3
  • 12
    • 34147092225 scopus 로고    scopus 로고
    • A CFSE based assay for measuring CD4+CD25+ regulatory T cell mediated suppression of auto-antigen specific and polyclonal T cell responses
    • Venken K, Thewissen M, Hellings N et al. A CFSE based assay for measuring CD4+CD25+ regulatory T cell mediated suppression of auto-antigen specific and polyclonal T cell responses. J Immunol Methods 2007; 322: 1-11.
    • (2007) J Immunol Methods , vol.322 , pp. 1-11
    • Venken, K.1    Thewissen, M.2    Hellings, N.3
  • 13
    • 34248345515 scopus 로고    scopus 로고
    • CD4+ CD25+ regulatory T cells suppress CD4+ T-cell function and inhibit the development of Plasmodium berghei-specific TH1 responses involved in cerebral malaria pathogenesis
    • Nie CQ, Bernard NJ, Schofield L et al. CD4+ CD25+ regulatory T cells suppress CD4+ T-cell function and inhibit the development of Plasmodium berghei-specific TH1 responses involved in cerebral malaria pathogenesis. Infect Immun 2007; 75: 2275-2282.
    • (2007) Infect Immun , vol.75 , pp. 2275-2282
    • Nie, C.Q.1    Bernard, N.J.2    Schofield, L.3
  • 14
    • 57149089909 scopus 로고    scopus 로고
    • Normal mouse kidneys contain activated and CD3+CD4- CD8- double-negative T lymphocytes with a distinct TCR repertoire
    • Ascon DB, Ascon M, Satpute S et al. Normal mouse kidneys contain activated and CD3+CD4- CD8- double-negative T lymphocytes with a distinct TCR repertoire. J Leukoc Biol 2008; 84: 1400-1409.
    • (2008) J Leukoc Biol , vol.84 , pp. 1400-1409
    • Ascon, D.B.1    Ascon, M.2    Satpute, S.3
  • 15
    • 77951092732 scopus 로고    scopus 로고
    • Regulatory T cells contribute to the protective effect of ischemic preconditioning in the kidney
    • Kinsey GR, Huang L, Vergis AL et al. Regulatory T cells contribute to the protective effect of ischemic preconditioning in the kidney. Kidney Int 2010; 77: 771-780.
    • (2010) Kidney Int , vol.77 , pp. 771-780
    • Kinsey, G.R.1    Huang, L.2    Vergis, A.L.3
  • 16
    • 70349208518 scopus 로고    scopus 로고
    • Foxp3+ regulatory T cells participate in repair of ischemic acute kidney injury
    • Gandolfo MT, Jang HR, Bagnasco SM et al. Foxp3+ regulatory T cells participate in repair of ischemic acute kidney injury. Kidney Int 2009; 76: 717-729.
    • (2009) Kidney Int , vol.76 , pp. 717-729
    • Gandolfo, M.T.1    Jang, H.R.2    Bagnasco, S.M.3
  • 17
    • 68049147686 scopus 로고    scopus 로고
    • Regulatory T cells suppress innate immunity in kidney ischemia-reperfusion injury
    • Kinsey GR, Sharma R, Huang L et al. Regulatory T cells suppress innate immunity in kidney ischemia-reperfusion injury. J Am Soc Nephrol 2009; 20: 1744-1753.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1744-1753
    • Kinsey, G.R.1    Sharma, R.2    Huang, L.3
  • 18
    • 84860368153 scopus 로고    scopus 로고
    • Pharmacologic recruitment of regulatory T cells as a therapy for ischemic acute kidney injury
    • Lai LW, Yong KC, Lien YH. Pharmacologic recruitment of regulatory T cells as a therapy for ischemic acute kidney injury. Kidney Int 2012; 81: 983-992.
    • (2012) Kidney Int , vol.81 , pp. 983-992
    • Lai, L.W.1    Yong, K.C.2    Lien, Y.H.3
  • 19
    • 73449133395 scopus 로고    scopus 로고
    • Human adipose-derived mesenchymal stem cells reduce inflammatory and T cell responses and induce regulatory T cells in vitro in rheumatoid arthritis
    • Gonzalez-Rey E, Gonzalez MA, Varela N et al. Human adipose-derived mesenchymal stem cells reduce inflammatory and T cell responses and induce regulatory T cells in vitro in rheumatoid arthritis. Ann Rheum Dis 2010; 69: 241-248.
    • (2010) Ann Rheum Dis , vol.69 , pp. 241-248
    • Gonzalez-Rey, E.1    Gonzalez, M.A.2    Varela, N.3
  • 20
    • 57849108938 scopus 로고    scopus 로고
    • Immunosuppressive effects of rat mesenchymal stem cells: Involvement of CD4+CD25+ regulatory T cells
    • Ye Z, Wang Y, Xie HY et al. Immunosuppressive effects of rat mesenchymal stem cells: Involvement of CD4+CD25+ regulatory T cells. Hepatobiliary Pancreat Dis Int 2008; 7: 608-614.
    • (2008) Hepatobiliary Pancreat Dis Int , vol.7 , pp. 608-614
    • Ye, Z.1    Wang, Y.2    Xie, H.Y.3
  • 21
    • 38349053355 scopus 로고    scopus 로고
    • Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD4+CD25highFOXP3+ regulatory T cells
    • Selmani Z, Naji A, Zidi I et al. Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD4+CD25highFOXP3+ regulatory T cells. Stem Cells 2008; 26: 212-222.
    • (2008) Stem Cells , vol.26 , pp. 212-222
    • Selmani, Z.1    Naji, A.2    Zidi, I.3
  • 22
    • 34548739534 scopus 로고    scopus 로고
    • Generation of CD4+ or CD8+ regulatory T cells upon mesenchymal stem cell-lymphocyte interaction
    • Prevosto C, Zancolli M, Canevali P et al. Generation of CD4+ or CD8+ regulatory T cells upon mesenchymal stem cell-lymphocyte interaction. Haematologica 2007; 92: 881-888.
    • (2007) Haematologica , vol.92 , pp. 881-888
    • Prevosto, C.1    Zancolli, M.2    Canevali, P.3
  • 23
    • 77954728855 scopus 로고    scopus 로고
    • Mesenchymal stem cells protect breast cancer cells through regulatory T cells: Role of mesenchymal stem cell-derived TGF-beta
    • Patel SA, Meyer JR, Greco SJ et al. Mesenchymal stem cells protect breast cancer cells through regulatory T cells: Role of mesenchymal stem cell-derived TGF-beta. J Immunol 2010; 184: 5885-5894.
    • (2010) J Immunol , vol.184 , pp. 5885-5894
    • Patel, S.A.1    Meyer, J.R.2    Greco, S.J.3
  • 24
    • 56149110595 scopus 로고    scopus 로고
    • Pretransplant infusion of mesenchymal stem cells prolongs the survival of a semiallogeneic heart transplant through the generation of regulatory T cells
    • Casiraghi F, Azzollini N, Cassis P et al. Pretransplant infusion of mesenchymal stem cells prolongs the survival of a semiallogeneic heart transplant through the generation of regulatory T cells. J Immunol 2008; 181: 3933-3946.
    • (2008) J Immunol , vol.181 , pp. 3933-3946
    • Casiraghi, F.1    Azzollini, N.2    Cassis, P.3
  • 25
    • 67349224622 scopus 로고    scopus 로고
    • Mesenchymal stem cells protect NOD mice from diabetes by inducing regulatory T cells
    • Madec AM, Mallone R, Afonso G et al. Mesenchymal stem cells protect NOD mice from diabetes by inducing regulatory T cells. Diabetologia 2009; 52: 1391-1399.
    • (2009) Diabetologia , vol.52 , pp. 1391-1399
    • Madec, A.M.1    Mallone, R.2    Afonso, G.3
  • 26
    • 79952313924 scopus 로고    scopus 로고
    • Bone marrow stromal cell transplants prevent experimental enterocolitis and require host CD11b+ splenocytes
    • Parekkadan B, Upadhyay R, Dunham J et al. Bone marrow stromal cell transplants prevent experimental enterocolitis and require host CD11b+ splenocytes. Gastroenterology 2011; 140: 966-975.
    • (2011) Gastroenterology , vol.140 , pp. 966-975
    • Parekkadan, B.1    Upadhyay, R.2    Dunham, J.3
  • 27
    • 79959461779 scopus 로고    scopus 로고
    • Intrapulmonary delivery of human umbilical cord mesenchymal stem cells attenuates acute lung injury by expanding CD4CD25(+) Forkhead Boxp3 (FOXP3) (+) regulatory T cells and balancing anti- and pro-inflammatory factors
    • Sun J, Han ZB, Liao W et al. Intrapulmonary delivery of human umbilical cord mesenchymal stem cells attenuates acute lung injury by expanding CD4CD25(+) Forkhead Boxp3 (FOXP3) (+) regulatory T cells and balancing anti- and pro-inflammatory factors. Cell Physiol Biochem 2011; 27: 587-596.
    • (2011) Cell Physiol Biochem , vol.27 , pp. 587-596
    • Sun, J.1    Han, Z.B.2    Liao, W.3
  • 28
    • 34147126415 scopus 로고    scopus 로고
    • Mesenchymal stem cells effectively modulate pathogenic immune response in experimental autoimmune encephalomyelitis
    • Gerdoni E, Gallo B, Casazza S et al. Mesenchymal stem cells effectively modulate pathogenic immune response in experimental autoimmune encephalomyelitis. Annal Neurol 2007; 61: 219-227.
    • (2007) Annal Neurol , vol.61 , pp. 219-227
    • Gerdoni, E.1    Gallo, B.2    Casazza, S.3
  • 29
    • 60449093316 scopus 로고    scopus 로고
    • Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis
    • Gonzalez-Rey E, Anderson P, Gonzalez MA et al. Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis. Gut 2009; 58: 929-939.
    • (2009) Gut , vol.58 , pp. 929-939
    • Gonzalez-Rey, E.1    Anderson, P.2    Gonzalez, M.A.3
  • 30
    • 0033826104 scopus 로고    scopus 로고
    • Pathophysiological role of T lymphocytes in renal ischemia-reperfusion injury in mice
    • Rabb H, Daniels F, O'Donnell M et al. Pathophysiological role of T lymphocytes in renal ischemia-reperfusion injury in mice. Am J Physiol Renal Physiol 2000; 279: F525-F531.
    • (2000) Am J Physiol Renal Physiol , vol.279
    • Rabb, H.1    Daniels, F.2    O'donnell, M.3
  • 31
    • 33845354040 scopus 로고    scopus 로고
    • Use of lipophilic near-infrared dye in whole-body optical imaging of hematopoietic cell homing
    • Kalchenko V, Shivtiel S, Malina V et al. Use of lipophilic near-infrared dye in whole-body optical imaging of hematopoietic cell homing. J Biomed Opt 2006; 11: 050507.
    • (2006) J Biomed Opt , vol.11 , pp. 050507
    • Kalchenko, V.1    Shivtiel, S.2    Malina, V.3
  • 32
    • 0348047537 scopus 로고    scopus 로고
    • The main function of IL-2 is to promote the development of T regulatory cells
    • Malek TR. The main function of IL-2 is to promote the development of T regulatory cells. J Leukoc Biol 2003; 74: 961-965.
    • (2003) J Leukoc Biol , vol.74 , pp. 961-965
    • Malek, T.R.1
  • 33
    • 15444374646 scopus 로고    scopus 로고
    • Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
    • Setoguchi R, Hori S, Takahashi T et al. Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. J Exp Med 2005; 201: 723-735.
    • (2005) J Exp Med , vol.201 , pp. 723-735
    • Setoguchi, R.1    Hori, S.2    Takahashi, T.3
  • 34
    • 8444245925 scopus 로고    scopus 로고
    • Toll-dependent control mechanisms of CD4 T cell activation
    • Pasare C, Medzhitov R. Toll-dependent control mechanisms of CD4 T cell activation. Immunity 2004; 21: 733-741.
    • (2004) Immunity , vol.21 , pp. 733-741
    • Pasare, C.1    Medzhitov, R.2
  • 35
    • 41949097030 scopus 로고    scopus 로고
    • The biology of interleukin-2
    • Malek TR. The biology of interleukin-2. Annu Rev Immunol 2008; 26: 453-479.
    • (2008) Annu Rev Immunol , vol.26 , pp. 453-479
    • Malek, T.R.1
  • 36
    • 36048973296 scopus 로고    scopus 로고
    • Ischemia-reperfusion and immediate T cell responses
    • Huang Y, Rabb H, Womer KL. Ischemia-reperfusion and immediate T cell responses. Cell Immunol 2007; 248: 4-11.
    • (2007) Cell Immunol , vol.248 , pp. 4-11
    • Huang, Y.1    Rabb, H.2    Womer, K.L.3
  • 37
    • 0023780625 scopus 로고
    • Nonequivalent effects of PKC activation by PMA on murine CD4 and CD8 cell-surface expression
    • Kaldjian E, McCarthy SA, Sharrow SO et al. Nonequivalent effects of PKC activation by PMA on murine CD4 and CD8 cell-surface expression. FASEB J 1988; 2: 2801-2806.
    • (1988) FASEB J , vol.2 , pp. 2801-2806
    • Kaldjian, E.1    McCarthy, S.A.2    Sharrow, S.O.3
  • 38
    • 55049087497 scopus 로고    scopus 로고
    • Human bone marrow mesenchymal stem cells accelerate recovery of acute renal injury and prolong survival in mice
    • Morigi M, Introna M, Imberti B et al. Human bone marrow mesenchymal stem cells accelerate recovery of acute renal injury and prolong survival in mice. Stem Cells 2008; 26: 2075-2082.
    • (2008) Stem Cells , vol.26 , pp. 2075-2082
    • Morigi, M.1    Introna, M.2    Imberti, B.3
  • 39
    • 67349204472 scopus 로고    scopus 로고
    • Repair of tissues by adult stem/progenitor cells (MSCs): Controversies, myths, and changing paradigms
    • Prockop DJ. Repair of tissues by adult stem/progenitor cells (MSCs): Controversies, myths, and changing paradigms. Mol Ther 2009; 17: 939-946.
    • (2009) Mol Ther , vol.17 , pp. 939-946
    • Prockop, D.J.1
  • 40
    • 67649171661 scopus 로고    scopus 로고
    • Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6
    • Lee RH, Pulin AA, Seo MJ et al. Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6. Cell Stem Cell 2009; 5: 54-63.
    • (2009) Cell Stem Cell , vol.5 , pp. 54-63
    • Lee, R.H.1    Pulin, A.A.2    Seo, M.J.3
  • 41
    • 38349077498 scopus 로고    scopus 로고
    • Toll-like receptors on human mesenchymal stem cells drive their migration and immunomodulating responses
    • Tomchuck SL, Zwezdaryk KJ, Coffelt SB et al. Toll-like receptors on human mesenchymal stem cells drive their migration and immunomodulating responses. Stem Cells 2008; 26: 99-107.
    • (2008) Stem Cells , vol.26 , pp. 99-107
    • Tomchuck, S.L.1    Zwezdaryk, K.J.2    Coffelt, S.B.3
  • 42
    • 20844462254 scopus 로고    scopus 로고
    • Persistent renal and extrarenal immune changes after severe ischemic injury
    • Burne-Taney MJ, Yokota N, Rabb H. Persistent renal and extrarenal immune changes after severe ischemic injury. Kidney Int 2005; 67: 1002-1009.
    • (2005) Kidney Int , vol.67 , pp. 1002-1009
    • Burne-Taney, M.J.1    Yokota, N.2    Rabb, H.3
  • 43
    • 0037364804 scopus 로고    scopus 로고
    • Natural versus adaptive regulatory T cells
    • Bluestone JA, Abbas AK. Natural versus adaptive regulatory T cells. Nat Rev Immunol 2003; 3: 253-257.
    • (2003) Nat Rev Immunol , vol.3 , pp. 253-257
    • Bluestone, J.A.1    Abbas, A.K.2
  • 44
    • 0035198718 scopus 로고    scopus 로고
    • Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes
    • Gonzalez A, Andre-Schmutz I, Carnaud C et al. Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes. Nat Immunol 2001; 2: 1117-1125.
    • (2001) Nat Immunol , vol.2 , pp. 1117-1125
    • Gonzalez, A.1    Andre-Schmutz, I.2    Carnaud, C.3
  • 45
    • 84856973179 scopus 로고    scopus 로고
    • Mesenchymal stem/stromal cells (MSCs): Role as guardians of inflammation
    • Prockop DJ, Oh JY. Mesenchymal stem/stromal cells (MSCs): Role as guardians of inflammation. Mol Ther 2012; 20: 14-20.
    • (2012) Mol Ther , vol.20 , pp. 14-20
    • Prockop, D.J.1    Oh, J.Y.2
  • 46
    • 70449527554 scopus 로고    scopus 로고
    • Mesenchymal stem cell-educated macrophages: A novel type of alternatively activated macrophages
    • Kim J, Hematti P. Mesenchymal stem cell-educated macrophages: A novel type of alternatively activated macrophages. Exp Hematol 2009; 37: 1445-1453.
    • (2009) Exp Hematol , vol.37 , pp. 1445-1453
    • Kim, J.1    Hematti, P.2
  • 47
    • 33646525690 scopus 로고    scopus 로고
    • S1P(1)-selective agonist, SEW2871, ameliorates ischemic acute renal failure
    • Lien YH, Yong KC, Cho C et al. S1P(1)-selective agonist, SEW2871, ameliorates ischemic acute renal failure. Kidney international 2006; 69: 1601-1608.
    • (2006) Kidney International , vol.69 , pp. 1601-1608
    • Lien, Y.H.1    Yong, K.C.2    Cho, C.3
  • 48
    • 0035015397 scopus 로고    scopus 로고
    • Impaired IL-18 processing protects caspase-1-deficient mice from ischemic acute renal failure
    • Melnikov VY, Ecder T, Fantuzzi G et al. Impaired IL-18 processing protects caspase-1-deficient mice from ischemic acute renal failure. J Clin Invest 2001; 107: 1145-1152.
    • (2001) J Clin Invest , vol.107 , pp. 1145-1152
    • Melnikov, V.Y.1    Ecder, T.2    Fantuzzi, G.3
  • 49
    • 31144439760 scopus 로고    scopus 로고
    • Qa-1b and CD94-NKG2a interaction regulate cytolytic activity of herpes simplex virus-specific memory CD8+ T cells in the latently infected trigeminal ganglia
    • Suvas S, Azkur AK, Rouse BT. Qa-1b and CD94-NKG2a interaction regulate cytolytic activity of herpes simplex virus-specific memory CD8+ T cells in the latently infected trigeminal ganglia. J Immunol 2006; 176: 1703-1711.
    • (2006) J Immunol , vol.176 , pp. 1703-1711
    • Suvas, S.1    Azkur, A.K.2    Rouse, B.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.