Enhancement of the synthesis of n-3 PUFAs in fat-1 transgenic mice inhibits mTORC1 signalling and delays surgically induced osteoarthritis in comparison with wild-type mice

Annals of the Rheumatic Diseases

Volumn 73, Issue 9, 2014, Pages 1719-1727

  Huang, Min Jun ^a,b   Wang, Liang ^a,b   Jin, Da Di ^a,b   Zhang, Zhong Min ^a,b   Chen, Tian Yu ^a,b   Jia, Chun Hong ^a   Wang, Yan ^c   Zhen, Xiao Chen ^a,b   Huang, Bin ^a,b   Yan, Bo ^a,b   Chen, Yu Hui ^a,b   Li, Sheng Fa ^a,b   Yang, Jin Cheng ^d   Dai, Yi Fan ^c   Bai, Xiao Chun ^a,b  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b Academy of Orthopedics   (China)

^c NANJING MEDICAL UNIVERSITY   (China)

^d Liuhuaqiao Hospital   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHONDROCYTES; CYTOKINES; INFLAMMATION; OSTEOARTHRITIS;

ADAM PROTEINS; ANIMALS; ARTHRITIS, EXPERIMENTAL; AUTOPHAGY; CADHERINS; CARTILAGE, ARTICULAR; CHONDROCYTES; DISEASE PROGRESSION; FATTY ACIDS, OMEGA-3; FATTY ACIDS, OMEGA-6; FEMALE; MATRIX METALLOPROTEINASE 13; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROSCOPY, ELECTRON, SCANNING; MULTIPROTEIN COMPLEXES; OSTEOARTHRITIS; PROTEOGLYCANS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84905179075     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2013-203231     Document Type: Article

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