Increased expression of (pro)renin receptor does not cause hypertension or cardiac and renal fibrosis in mice

Laboratory Investigation

Volumn 94, Issue 8, 2014, Pages 863-872

  Rosendahl, Alva ^a   Niemann, Gianina ^a   Lange, Sascha ^a   Ahadzadeh, Erfan ^a   Krebs, Christian ^a   Contrepas, Aurelie ^b,c,d,i   Van Goor, Harry ^e   Wiech, Thorsten ^a   Bader, Michael ^f   Schwake, Michael ^g   Peters, Judith ^h   Stahl, Rolf ^a   Nguyen, Geneviève ^b,c,d   Wenzel, Ulrich O ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b INSERM   (France)

^c PSL RESEARCH UNIVERSITY   (France)

^d CNRS   (France)

^e UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^f MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^g BIELEFELD UNIVERSITY   (Germany)

^h UNIVERSITY OF KIEL   (Germany)

ⁱ HealthExperts SAS 6 Cité de l'Ameublement   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; LOSARTAN; PRORENIN RECEPTOR; RENIN;

ALBUMINURIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATP6AP2 GENE; BACKCROSSING; CONTROLLED STUDY; ENHANCER REGION; GENE LOCUS; GENE OVEREXPRESSION; GENE TARGETING; GLOMERULOSCLEROSIS; HEART INJURY; HEART MUSCLE FIBROSIS; HEART WEIGHT; HISTOLOGY; HYPERTENSION; KIDNEY FIBROSIS; KIDNEY INJURY; KIDNEY MASS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PRR GENE; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR GENE; SOUTHERN BLOTTING; SYSTOLIC BLOOD PRESSURE; TRANSGENE; WILD TYPE;

ALBUMINURIA; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; FEMALE; FIBROSIS; HEART VENTRICLES; HEMIZYGOTE; HETEROZYGOTE; HOMOZYGOTE; HYPERTENSION; INFLAMMATION MEDIATORS; KIDNEY; LOSARTAN; MALE; MICE; MICE, INBRED STRAINS; MICE, TRANSGENIC; PROTON-TRANSLOCATING ATPASES; RECEPTORS, CELL SURFACE; RENAL INSUFFICIENCY; RENIN; UP-REGULATION; VENTRICULAR DYSFUNCTION;

EID: 84905158805     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2014.83     Document Type: Article

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