-
2
-
-
77949536656
-
Tissue renin-angiotensin-aldosterone systems: targets for pharmacological therapy
-
Bader M, (2010) Tissue renin-angiotensin-aldosterone systems: targets for pharmacological therapy. Annu Rev Pharmacol Toxicol 50: 439-465.
-
(2010)
Annu Rev Pharmacol Toxicol
, vol.50
, pp. 439-465
-
-
Bader, M.1
-
3
-
-
0036266596
-
Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
-
Nguyen G, Delarue F, Burcklé C, Bouzhir L, Giller T, et al. (2002) Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 109: 1417-1427.
-
(2002)
J Clin Invest
, vol.109
, pp. 1417-1427
-
-
Nguyen, G.1
Delarue, F.2
Burcklé, C.3
Bouzhir, L.4
Giller, T.5
-
4
-
-
33644983896
-
Elevated blood pressure and heart rate in human renin receptor transgenic rats
-
Burcklé CA, Jan Danser AH, Müller DN, Garrelds IM, Gasc JM, et al. (2006) Elevated blood pressure and heart rate in human renin receptor transgenic rats. Hypertension 47: 552-556.
-
(2006)
Hypertension
, vol.47
, pp. 552-556
-
-
Burcklé, C.A.1
Jan Danser, A.H.2
Müller, D.N.3
Garrelds, I.M.4
Gasc, J.M.5
-
5
-
-
33747060126
-
Increased expression of cyclooxygenase-2 in the renal cortex of human prorenin receptor gene-transgenic rats
-
Kaneshiro Y, Ichihara A, Takemitsu T, Sakoda M, Suzuki F, et al. (2006) Increased expression of cyclooxygenase-2 in the renal cortex of human prorenin receptor gene-transgenic rats. Kidney Int 70: 641-646.
-
(2006)
Kidney Int
, vol.70
, pp. 641-646
-
-
Kaneshiro, Y.1
Ichihara, A.2
Takemitsu, T.3
Sakoda, M.4
Suzuki, F.5
-
6
-
-
34249881320
-
Slowly progressive, angiotensin II-independent glomerulosclerosis in human (pro)renin receptor-transgenic rats
-
Kaneshiro Y, Ichihara A, Sakoda M, Takemitsu T, Nabi AH, et al. (2007) Slowly progressive, angiotensin II-independent glomerulosclerosis in human (pro)renin receptor-transgenic rats. J Am Soc Nephrol 18: 1789-1795.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 1789-1795
-
-
Kaneshiro, Y.1
Ichihara, A.2
Sakoda, M.3
Takemitsu, T.4
Nabi, A.H.5
-
7
-
-
42249089770
-
The putative (pro)renin receptor blocker HRP fails to prevent (pro)renin signaling
-
Feldt S, Maschke U, Dechend R, Luft FC, Muller DN, (2008) The putative (pro)renin receptor blocker HRP fails to prevent (pro)renin signaling. J Am Soc Nephrol 19: 743-748.
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 743-748
-
-
Feldt, S.1
Maschke, U.2
Dechend, R.3
Luft, F.C.4
Muller, D.N.5
-
8
-
-
68549111147
-
The (Pro)renin receptor: site-specific and functional linkage to the vacuolar H+-ATPase in the kidney
-
Advani A, Kelly DJ, Cox AJ, White KE, Advani SL, et al. (2009) The (Pro)renin receptor: site-specific and functional linkage to the vacuolar H+-ATPase in the kidney. Hypertension 54: 261-269.
-
(2009)
Hypertension
, vol.54
, pp. 261-269
-
-
Advani, A.1
Kelly, D.J.2
Cox, A.J.3
White, K.E.4
Advani, S.L.5
-
9
-
-
75649120756
-
Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling
-
Cruciat CM, Ohkawara B, Acebron SP, Karaulanov E, Reinhard C, et al. (2010) Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling. Science 327: 459-463.
-
(2010)
Science
, vol.327
, pp. 459-463
-
-
Cruciat, C.M.1
Ohkawara, B.2
Acebron, S.P.3
Karaulanov, E.4
Reinhard, C.5
-
10
-
-
77954762963
-
The (pro)renin receptor/ATP6AP2 is essential for vacuolar H+-ATPase assembly in murine cardiomyocytes
-
Kinouchi K, Ichihara A, Sano M, Sun-Wada GH, Wada Y, et al. (2010) The (pro)renin receptor/ATP6AP2 is essential for vacuolar H+-ATPase assembly in murine cardiomyocytes. Circ Res 107: 30-34.
-
(2010)
Circ Res
, vol.107
, pp. 30-34
-
-
Kinouchi, K.1
Ichihara, A.2
Sano, M.3
Sun-Wada, G.H.4
Wada, Y.5
-
11
-
-
33845598077
-
p38 Kinase rescues failing myocardium after myocardial infarction: evidence for angiogenic and anti-apoptotic mechanisms
-
Tenhunen O, Soini Y, Ilves M, Rysä J, Tuukkanen J, et al. (2006) p38 Kinase rescues failing myocardium after myocardial infarction: evidence for angiogenic and anti-apoptotic mechanisms. FASEB 20: 1907-1909.
-
(2006)
FASEB
, vol.20
, pp. 1907-1909
-
-
Tenhunen, O.1
Soini, Y.2
Ilves, M.3
Rysä, J.4
Tuukkanen, J.5
-
12
-
-
0035142395
-
In vivo acceleration of heart relaxation performance by parvalbumin gene delivery
-
Szatkowski ML, Westjall MV, Gomez CA, Wahr PA, Michele DE, et al. (2001) In vivo acceleration of heart relaxation performance by parvalbumin gene delivery. J Clin Invest 107: 191-198.
-
(2001)
J Clin Invest
, vol.107
, pp. 191-198
-
-
Szatkowski, M.L.1
Westjall, M.V.2
Gomez, C.A.3
Wahr, P.A.4
Michele, D.E.5
-
13
-
-
33748375134
-
Identification of cell cycle regulatory and inflammatory genes as predominant targets of p38 MAPK in the heart
-
Tenhunen O, Rysä J, Ilves M, Ruskoaho H, Leskinen H, (2006) Identification of cell cycle regulatory and inflammatory genes as predominant targets of p38 MAPK in the heart. Circ Res 99: 485-493.
-
(2006)
Circ Res
, vol.99
, pp. 485-493
-
-
Tenhunen, O.1
Rysä, J.2
Ilves, M.3
Ruskoaho, H.4
Leskinen, H.5
-
14
-
-
77954710191
-
GATA-4 is an angiogenic survival factor of the infarcted heart
-
Rysä J, Tenhunen O, Serpi R, Soini Y, Nemer M, et al. (2010) GATA-4 is an angiogenic survival factor of the infarcted heart. Circ Heart Fail 3: 440-450.
-
(2010)
Circ Heart Fail
, vol.3
, pp. 440-450
-
-
Rysä, J.1
Tenhunen, O.2
Serpi, R.3
Soini, Y.4
Nemer, M.5
-
15
-
-
80052808787
-
Intramyocardial BNP gene delivery improves cardiac function through distinct context-dependent mechanisms
-
Moilanen AM, Rysä J, Mustonen E, Serpi R, Aro J, et al. (2011) Intramyocardial BNP gene delivery improves cardiac function through distinct context-dependent mechanisms. Circ Heart Fail 4: 483-495.
-
(2011)
Circ Heart Fail
, vol.4
, pp. 483-495
-
-
Moilanen, A.M.1
Rysä, J.2
Mustonen, E.3
Serpi, R.4
Aro, J.5
-
16
-
-
33646160993
-
Nonproteolytic activation of prorenin contributes to development of cardiac fibrosis in genetic hypertension
-
Ichihara A, Kaneshiro Y, Takemitsu T, Sakoda M, Suzuki F, et al. (2006) Nonproteolytic activation of prorenin contributes to development of cardiac fibrosis in genetic hypertension. Hypertension 47: 894-900.
-
(2006)
Hypertension
, vol.47
, pp. 894-900
-
-
Ichihara, A.1
Kaneshiro, Y.2
Takemitsu, T.3
Sakoda, M.4
Suzuki, F.5
-
17
-
-
70449646204
-
Gene expression of (pro)renin receptor is upregulated in hearts and kidneys of rats with congestive heart failure
-
Hirose T, Mori N, Totsune K, Morimoto R, Maejima T, et al. (2009) Gene expression of (pro)renin receptor is upregulated in hearts and kidneys of rats with congestive heart failure. Peptides 30: 2316-2322.
-
(2009)
Peptides
, vol.30
, pp. 2316-2322
-
-
Hirose, T.1
Mori, N.2
Totsune, K.3
Morimoto, R.4
Maejima, T.5
-
18
-
-
84864195516
-
Regulation of the (pro)renin-renin receptor in cardiac remodeling
-
doi:10.1111/j.1582-4934.2011.01377.x
-
Mahmud H, Silljé HH, Cannon MV, van Gilst WH, de Boer RA, (2011) Regulation of the (pro)renin-renin receptor in cardiac remodeling. J Cell Mol Med doi:10.1111/j.1582-4934.2011.01377.x.
-
(2011)
J Cell Mol Med
-
-
Mahmud, H.1
Silljé, H.H.2
Cannon, M.V.3
van Gilst, W.H.4
de Boer, R.A.5
-
19
-
-
77953367249
-
Divergent effects of losartan and metoprolol on cardiac remodeling, c-kit+ cells, proliferation and apoptosis in the left ventricle after myocardial infarction
-
Serpi R, Tolonen AM, Tenhunen O, Pieviläinen O, Kubin AM, et al. (2009) Divergent effects of losartan and metoprolol on cardiac remodeling, c-kit+ cells, proliferation and apoptosis in the left ventricle after myocardial infarction. Clin Transl Sci 2: 422-430.
-
(2009)
Clin Transl Sci
, vol.2
, pp. 422-430
-
-
Serpi, R.1
Tolonen, A.M.2
Tenhunen, O.3
Pieviläinen, O.4
Kubin, A.M.5
-
20
-
-
0242694527
-
Evidence for a functional role of angiotensin II type 2 receptor in the cardiac hypertrophic process in vivo in the rat heart
-
Lakó-Futó Z, Szokodi I, Sármán B, Földes G, Tokola H, et al. (2003) Evidence for a functional role of angiotensin II type 2 receptor in the cardiac hypertrophic process in vivo in the rat heart. Circulation 108: 2414-2422.
-
(2003)
Circulation
, vol.108
, pp. 2414-2422
-
-
Lakó-Futó, Z.1
Szokodi, I.2
Sármán, B.3
Földes, G.4
Tokola, H.5
-
21
-
-
0030711490
-
Involvement of transcriptional and posttranscriptional mechanisms in cardiac overload-induced increase of B-type natriuretic peptide gene expression
-
Magga J, Vuolteenaho O, Tokola H, Marttila M, Ruskoaho H, (1997) Involvement of transcriptional and posttranscriptional mechanisms in cardiac overload-induced increase of B-type natriuretic peptide gene expression. Circ Res 81: 694-702.
-
(1997)
Circ Res
, vol.81
, pp. 694-702
-
-
Magga, J.1
Vuolteenaho, O.2
Tokola, H.3
Marttila, M.4
Ruskoaho, H.5
-
22
-
-
0035814764
-
Pressure overload increases GATA4 binding activity via endothelin-1
-
Hautala N, Tokola H, Luodonpää M, Puhakka J, Romppanen H, et al. (2001) Pressure overload increases GATA4 binding activity via endothelin-1. Circulation 103: 730-735.
-
(2001)
Circulation
, vol.103
, pp. 730-735
-
-
Hautala, N.1
Tokola, H.2
Luodonpää, M.3
Puhakka, J.4
Romppanen, H.5
-
23
-
-
2642568647
-
Mitogen-activated protein kinases p38 and ERK 1/2 mediate the wall stress-induced activation of GATA-4 binding in adult heart
-
Tenhunen O, Sarman B, Kerkelä R, Szokodi I, Papp L, et al. (2004) Mitogen-activated protein kinases p38 and ERK 1/2 mediate the wall stress-induced activation of GATA-4 binding in adult heart. J Biol Chem 279: 24852-24860.
-
(2004)
J Biol Chem
, vol.279
, pp. 24852-24860
-
-
Tenhunen, O.1
Sarman, B.2
Kerkelä, R.3
Szokodi, I.4
Papp, L.5
-
24
-
-
18244385727
-
Distinct upregulation of extracellular matrix genes in transition from hypertrophy to hypertensive heart failure
-
Rysä J, Leskinen H, Ilves M, Ruskoaho H, (2005) Distinct upregulation of extracellular matrix genes in transition from hypertrophy to hypertensive heart failure. Hypertension 45: 927-933.
-
(2005)
Hypertension
, vol.45
, pp. 927-933
-
-
Rysä, J.1
Leskinen, H.2
Ilves, M.3
Ruskoaho, H.4
-
25
-
-
0037590989
-
Endostatin inhibits human tongue carcinoma cell invasion and intravasation and blocks the activation of matrix metalloprotease-2, -9, and -13
-
Nyberg P, Heikkilä P, Sorsa T, Luostarinen J, Heljasvaara R, et al. (2003) Endostatin inhibits human tongue carcinoma cell invasion and intravasation and blocks the activation of matrix metalloprotease-2,-9, and-13. J Biol Chem 278: 22404-22411.
-
(2003)
J Biol Chem
, vol.278
, pp. 22404-22411
-
-
Nyberg, P.1
Heikkilä, P.2
Sorsa, T.3
Luostarinen, J.4
Heljasvaara, R.5
-
26
-
-
0029987762
-
Hepatocellular carcinomas with a high proliferation index and a low degree of apoptosis and necrosis are associated with a shortened survival
-
Soini Y, Virkajärvi N, Lehto V-P, Pääkkö P, (1996) Hepatocellular carcinomas with a high proliferation index and a low degree of apoptosis and necrosis are associated with a shortened survival. Br J Cancer 73: 1025-1030.
-
(1996)
Br J Cancer
, vol.73
, pp. 1025-1030
-
-
Soini, Y.1
Virkajärvi, N.2
Lehto, V.-P.3
Pääkkö, P.4
-
27
-
-
79955604483
-
The cardiac (pro)renin receptor is primarily expressed in myocyte transverse tubules and is increased in experimental diabetic cardiomyopathy
-
Connelly KA, Advani A, Kim S, Advani SL, Zhang M, et al. (2011) The cardiac (pro)renin receptor is primarily expressed in myocyte transverse tubules and is increased in experimental diabetic cardiomyopathy. J Hypertens 29: 1175-1184.
-
(2011)
J Hypertens
, vol.29
, pp. 1175-1184
-
-
Connelly, K.A.1
Advani, A.2
Kim, S.3
Advani, S.L.4
Zhang, M.5
-
28
-
-
0027944524
-
Direct in vivo gene transfer into porcine myocardium using replication-deficient adenoviral vectors
-
French BA, Mazur W, Geske RS, Bolli R, (1994) Direct in vivo gene transfer into porcine myocardium using replication-deficient adenoviral vectors. Circulation 90: 2414-2424.
-
(1994)
Circulation
, vol.90
, pp. 2414-2424
-
-
French, B.A.1
Mazur, W.2
Geske, R.S.3
Bolli, R.4
-
29
-
-
0027527177
-
Efficient gene transfer into myocardium by direct injection of adenovirus vectors
-
Guzman RJ, Lemarchand P, Crystal RG, Epstein SE, Finkel T, (1993) Efficient gene transfer into myocardium by direct injection of adenovirus vectors. Circ Res 73: 1202-1207.
-
(1993)
Circ Res
, vol.73
, pp. 1202-1207
-
-
Guzman, R.J.1
Lemarchand, P.2
Crystal, R.G.3
Epstein, S.E.4
Finkel, T.5
-
30
-
-
0027014358
-
Atrial natriuretic peptide: synthesis, release and metabolism
-
Ruskoaho H, (1992) Atrial natriuretic peptide: synthesis, release and metabolism. Pharmacol Rev 44: 479-602.
-
(1992)
Pharmacol Rev
, vol.44
, pp. 479-602
-
-
Ruskoaho, H.1
-
31
-
-
0002537440
-
Cardiac hypertrophy: the good, the bad, and the ugly
-
Frey N, Olson EN, (2003) Cardiac hypertrophy: the good, the bad, and the ugly. Annu Rev Physiol 65: 45-79.
-
(2003)
Annu Rev Physiol
, vol.65
, pp. 45-79
-
-
Frey, N.1
Olson, E.N.2
-
32
-
-
77149123965
-
Ca2+ cycling and new therapeutic approaches for heart failure
-
Lompré AM, Hajjar RJ, Harding SE, Kranias EG, Lohse MJ, et al. (2010) Ca2+ cycling and new therapeutic approaches for heart failure. Circulation 121: 822-830.
-
(2010)
Circulation
, vol.121
, pp. 822-830
-
-
Lompré, A.M.1
Hajjar, R.J.2
Harding, S.E.3
Kranias, E.G.4
Lohse, M.J.5
-
33
-
-
77955426828
-
Vascular endothelial growth factor (VEGF)-A: Role on cardiac angiogenesis following myocardial infarction
-
Zhao T, Zhao W, Chen Y, Ahokas RA, Sun Y, (2010) Vascular endothelial growth factor (VEGF)-A: Role on cardiac angiogenesis following myocardial infarction. Microvasc Res 80: 188-194.
-
(2010)
Microvasc Res
, vol.80
, pp. 188-194
-
-
Zhao, T.1
Zhao, W.2
Chen, Y.3
Ahokas, R.A.4
Sun, Y.5
-
34
-
-
0037216633
-
Biological activities of fibroblast growth factor-2 in the adult myocardium
-
Detillieux KA, Sheikh F, Kardami E, Cattini PA, (2003) Biological activities of fibroblast growth factor-2 in the adult myocardium. Cardiovasc Res 57: 8-19.
-
(2003)
Cardiovasc Res
, vol.57
, pp. 8-19
-
-
Detillieux, K.A.1
Sheikh, F.2
Kardami, E.3
Cattini, P.A.4
-
35
-
-
33845608395
-
A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein
-
Schefe JH, Menk M, Reinemund J, Effertz K, Hobbs RM, et al. (2006) A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein. Circ Res 99: 1355-1366.
-
(2006)
Circ Res
, vol.99
, pp. 1355-1366
-
-
Schefe, J.H.1
Menk, M.2
Reinemund, J.3
Effertz, K.4
Hobbs, R.M.5
-
36
-
-
79251621720
-
Renin, pro(renin) and receptor: an update
-
Nguyen G, (2011) Renin, pro(renin) and receptor: an update. Clin Sci 120: 169-178.
-
(2011)
Clin Sci
, vol.120
, pp. 169-178
-
-
Nguyen, G.1
-
37
-
-
79953196418
-
Handle region peptide counteracts the beneficial effects of the Renin inhibitor aliskiren in spontaneously hypertensive rats
-
van Esch JH, van Veghel R, Garrelds IM, Leijten F, Bouhuizen AM, et al. (2011) Handle region peptide counteracts the beneficial effects of the Renin inhibitor aliskiren in spontaneously hypertensive rats. Hypertension 57: 852-858.
-
(2011)
Hypertension
, vol.57
, pp. 852-858
-
-
van Esch, J.H.1
van Veghel, R.2
Garrelds, I.M.3
Leijten, F.4
Bouhuizen, A.M.5
-
38
-
-
13844312743
-
The cardiac fibroblast: therapeutic target in myocardial remodeling and failure
-
Brown RD, Ambler SK, Mitchell MD, Long CS, (2005) The cardiac fibroblast: therapeutic target in myocardial remodeling and failure. Annu Rev Pharmacol Toxicol 45: 657-87.
-
(2005)
Annu Rev Pharmacol Toxicol
, vol.45
, pp. 657-687
-
-
Brown, R.D.1
Ambler, S.K.2
Mitchell, M.D.3
Long, C.S.4
-
39
-
-
14644414790
-
Protein kinase cascades in the regulation of cardiac hypertrophy
-
Dorn GW, Force T, (2005) Protein kinase cascades in the regulation of cardiac hypertrophy. J Clin Invest 115: 527-537.
-
(2005)
J Clin Invest
, vol.115
, pp. 527-537
-
-
Dorn, G.W.1
Force, T.2
-
40
-
-
33748323383
-
Regulation of cardiac hypertrophy by intracellular signaling pathways
-
Heineke J, Molkentin JD, (2006) Regulation of cardiac hypertrophy by intracellular signaling pathways. Nat Rev Mol Cell Biol 7: 589-600.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 589-600
-
-
Heineke, J.1
Molkentin, J.D.2
-
41
-
-
36048988646
-
Cardiac growth and angiogenesis coordinated by intertissue interactions
-
Walsh K, Shiojima I, (2007) Cardiac growth and angiogenesis coordinated by intertissue interactions. J Clin Invest 117: 3176-3179.
-
(2007)
J Clin Invest
, vol.117
, pp. 3176-3179
-
-
Walsh, K.1
Shiojima, I.2
-
42
-
-
0842281652
-
Rho and Rac take center stage
-
Burridge K, Wennerberg K, (2004) Rho and Rac take center stage. Cell 116: 167-179.
-
(2004)
Cell
, vol.116
, pp. 167-179
-
-
Burridge, K.1
Wennerberg, K.2
-
43
-
-
77951901715
-
Cell death in the pathogenesis of heart disease: mechanisms and significance
-
Whelan RS, Kaplinskiy V, Kitsis RN, (2010) Cell death in the pathogenesis of heart disease: mechanisms and significance. Annu Rev Physiol 72: 19-44.
-
(2010)
Annu Rev Physiol
, vol.72
, pp. 19-44
-
-
Whelan, R.S.1
Kaplinskiy, V.2
Kitsis, R.N.3
-
44
-
-
17144439543
-
Enhanced cardiac contractility after gene transfer of V2 vasopressin receptors In vivo by ultrasound-guided injection or transcoronary delivery
-
Weig HJ, Laugwitz KL, Moretti A, Kronsbein K, Städele C, et al. (2000) Enhanced cardiac contractility after gene transfer of V2 vasopressin receptors In vivo by ultrasound-guided injection or transcoronary delivery. Circulation 101: 1578-1585.
-
(2000)
Circulation
, vol.101
, pp. 1578-1585
-
-
Weig, H.J.1
Laugwitz, K.L.2
Moretti, A.3
Kronsbein, K.4
Städele, C.5
-
45
-
-
83155180323
-
Renin- and prorenin-induced effects in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor: does (pro)renin-(pro)renin receptor interaction actually occur?
-
Batenburg WW, Lu X, Leijten F, Maschke U, Müller DN, et al. (2011) Renin- and prorenin-induced effects in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor: does (pro)renin-(pro)renin receptor interaction actually occur? Hypertension 58: 1111-1119.
-
(2011)
Hypertension
, vol.58
, pp. 1111-1119
-
-
Batenburg, W.W.1
Lu, X.2
Leijten, F.3
Maschke, U.4
Müller, D.N.5
|