메뉴 건너뛰기




Volumn 109, Issue 7, 2007, Pages 2832-2839

Adenovirus-induced thrombocytopenia: The role of von Willebrand factor and P-selectin in mediating accelerated platelet clearance

Author keywords

[No Author keywords available]

Indexed keywords

COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR; FIBRONECTIN; PADGEM PROTEIN; POLYMER; VASCULAR CELL ADHESION MOLECULE 1; VON WILLEBRAND FACTOR;

EID: 33947604779     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2006-06-032524     Document Type: Article
Times cited : (190)

References (52)
  • 1
    • 0036147236 scopus 로고    scopus 로고
    • Toxicity of a first generation adenoviral vector in Rhesus macaques
    • Lozier J, Csako G, Mondoro TH, et al. Toxicity of a first generation adenoviral vector in Rhesus macaques. Hum Gene Ther. 2002;13:113-124.
    • (2002) Hum Gene Ther , vol.13 , pp. 113-124
    • Lozier, J.1    Csako, G.2    Mondoro, T.H.3
  • 2
    • 0033181742 scopus 로고    scopus 로고
    • Intravenous administration of recombinant adenoviruses causes thrombocytopenia, anemia and erythroblastosis in rabbits
    • Cichon G, Schmidt HH, Benhidjeb T, et al. Intravenous administration of recombinant adenoviruses causes thrombocytopenia, anemia and erythroblastosis in rabbits. J Gene Med. 1999;1:360-371.
    • (1999) J Gene Med , vol.1 , pp. 360-371
    • Cichon, G.1    Schmidt, H.H.2    Benhidjeb, T.3
  • 3
    • 15444366434 scopus 로고    scopus 로고
    • Evaluation of toxicity from high-dose systemic administration of recombinant adenovirus vector in vector-naive and pre-immunized mice
    • Varnavski AN, Calcedo R, Bove M, Gao G, Wilson JM. Evaluation of toxicity from high-dose systemic administration of recombinant adenovirus vector in vector-naive and pre-immunized mice. Gene Ther. 2005;12:427-436.
    • (2005) Gene Ther , vol.12 , pp. 427-436
    • Varnavski, A.N.1    Calcedo, R.2    Bove, M.3    Gao, G.4    Wilson, J.M.5
  • 4
    • 0038603921 scopus 로고    scopus 로고
    • The role of selectins in inflammation and disease
    • Ley K. The role of selectins in inflammation and disease. Trends Mol Med. 2003;9:263-268.
    • (2003) Trends Mol Med , vol.9 , pp. 263-268
    • Ley, K.1
  • 5
    • 0027828294 scopus 로고
    • Enhanced lymphocyte proliferative responses to donor-specific aortic endothelial cells following influenza vaccination
    • Wagner CR, Hosenpud JD. Enhanced lymphocyte proliferative responses to donor-specific aortic endothelial cells following influenza vaccination. Transpl Immunol. 1993;1:83-85.
    • (1993) Transpl Immunol , vol.1 , pp. 83-85
    • Wagner, C.R.1    Hosenpud, J.D.2
  • 6
    • 0034678355 scopus 로고    scopus 로고
    • P-selectin glycoprotein ligand 1 (PSGL-1) is expressed on platelets and can mediate platelet-endothelial interactions in vivo
    • Frenette PS, Denis CV, Weiss L, et al. P-selectin glycoprotein ligand 1 (PSGL-1) is expressed on platelets and can mediate platelet-endothelial interactions in vivo. J Exp Med. 2000;191:1413-1422.
    • (2000) J Exp Med , vol.191 , pp. 1413-1422
    • Frenette, P.S.1    Denis, C.V.2    Weiss, L.3
  • 7
    • 28344441333 scopus 로고    scopus 로고
    • The P-selectin, tissue factor, coagulation triad
    • Polgar J, Matuskova J, Wagner DD. The P-selectin, tissue factor, coagulation triad. J Thromb Haemost. 2005;3:1590-1596.
    • (2005) J Thromb Haemost , vol.3 , pp. 1590-1596
    • Polgar, J.1    Matuskova, J.2    Wagner, D.D.3
  • 8
    • 0028968252 scopus 로고
    • Regulation of function and expression of P-selectin
    • McEver RP. Regulation of function and expression of P-selectin. Agents Actions Suppl. 1995;47:117-119.
    • (1995) Agents Actions Suppl , vol.47 , pp. 117-119
    • McEver, R.P.1
  • 9
    • 0026507959 scopus 로고
    • Characterization of GMP-140 (P-selectin) as a circulating plasma protein
    • Dunlop LC, Skinner MP, Bendall LJ, et al. Characterization of GMP-140 (P-selectin) as a circulating plasma protein. J Exp Med. 1992;175:1147-1150.
    • (1992) J Exp Med , vol.175 , pp. 1147-1150
    • Dunlop, L.C.1    Skinner, M.P.2    Bendall, L.J.3
  • 10
    • 0032400835 scopus 로고    scopus 로고
    • P-Selectin and platelet clearance
    • Berger G, Hartwell DW, Wagner DD. P-Selectin and platelet clearance. Blood. 1998;92:4446-4452.
    • (1998) Blood , vol.92 , pp. 4446-4452
    • Berger, G.1    Hartwell, D.W.2    Wagner, D.D.3
  • 11
    • 0030801897 scopus 로고    scopus 로고
    • Soluble monomeric P-selectin containing only the lectin and epidermal growth factor domains binds to P-selectin glycoprotein ligand-1 on leukocytes
    • Mehta P, Patel KD, Laue TM, Erickson HP, McEver RP. Soluble monomeric P-selectin containing only the lectin and epidermal growth factor domains binds to P-selectin glycoprotein ligand-1 on leukocytes. Blood. 1997;90:2381-2389.
    • (1997) Blood , vol.90 , pp. 2381-2389
    • Mehta, P.1    Patel, K.D.2    Laue, T.M.3    Erickson, H.P.4    McEver, R.P.5
  • 13
    • 3242778632 scopus 로고    scopus 로고
    • Levels of soluble adhesion molecules in various clinical presentations of coronary atherosclerosis
    • Guray U, Erbay AR, Guray Y, et al. Levels of soluble adhesion molecules in various clinical presentations of coronary atherosclerosis. Int J Cardiol. 2004;96:235-240.
    • (2004) Int J Cardiol , vol.96 , pp. 235-240
    • Guray, U.1    Erbay, A.R.2    Guray, Y.3
  • 14
    • 0031686041 scopus 로고    scopus 로고
    • Biochemistry and genetics of von Willebrand factor
    • Sadler JE. Biochemistry and genetics of von Willebrand factor. Annu Rev Biochem. 1998;67:395-424.
    • (1998) Annu Rev Biochem , vol.67 , pp. 395-424
    • Sadler, J.E.1
  • 15
    • 0033588901 scopus 로고    scopus 로고
    • The glycoprotein Ib-IX-V complex is a platelet counterreceptor for P-selectin
    • Romo GM, Dong JF, Schade AJ, et al. The glycoprotein Ib-IX-V complex is a platelet counterreceptor for P-selectin. J Exp Med. 1999;190:803-814.
    • (1999) J Exp Med , vol.190 , pp. 803-814
    • Romo, G.M.1    Dong, J.F.2    Schade, A.J.3
  • 16
    • 0020355947 scopus 로고
    • Immunolocalization of von Willebrand protein in Weibel-Palade bodies of human endothelial cells
    • Wagner DD, Olmsted JB, Marder VJ. Immunolocalization of von Willebrand protein in Weibel-Palade bodies of human endothelial cells. J Cell Biol. 1982;95:355-360.
    • (1982) J Cell Biol , vol.95 , pp. 355-360
    • Wagner, D.D.1    Olmsted, J.B.2    Marder, V.J.3
  • 17
    • 0027935309 scopus 로고
    • Leukocyte-endothelial adhesion molecules
    • Carlos TM, Harlan JM. Leukocyte-endothelial adhesion molecules. Blood. 1994;84:2068-2101.
    • (1994) Blood , vol.84 , pp. 2068-2101
    • Carlos, T.M.1    Harlan, J.M.2
  • 18
    • 23944438008 scopus 로고    scopus 로고
    • Platelets adhered to endothelial cell-bound ultra-large von Willebrand factor strings support leukocyte tethering and rolling under high shear stress
    • Bernardo A, Ball C, Nolasco L, Choi H, Moake JL, Dong JF. Platelets adhered to endothelial cell-bound ultra-large von Willebrand factor strings support leukocyte tethering and rolling under high shear stress. J Thromb Haemost. 2005;3:562-570.
    • (2005) J Thromb Haemost , vol.3 , pp. 562-570
    • Bernardo, A.1    Ball, C.2    Nolasco, L.3    Choi, H.4    Moake, J.L.5    Dong, J.F.6
  • 19
    • 0034679329 scopus 로고    scopus 로고
    • Platelet glycoprotein ibalpha is a counterreceptor for the leukocyte integrin Mac-1 (CD11b/CD18)
    • Simon DI, Chen Z, Xu H, et al. Platelet glycoprotein ibalpha is a counterreceptor for the leukocyte integrin Mac-1 (CD11b/CD18). J Exp Med. 2000;192:193-204.
    • (2000) J Exp Med , vol.192 , pp. 193-204
    • Simon, D.I.1    Chen, Z.2    Xu, H.3
  • 20
    • 0030726989 scopus 로고    scopus 로고
    • Neutrophil accumulation on activated, surface-adherent platelets in flow is mediated by interaction of Mac-1 with fibrinogen bound to alphaIIbbeta3 and stimulated by platelet-activating factor
    • Weber C, Springer TA. Neutrophil accumulation on activated, surface-adherent platelets in flow is mediated by interaction of Mac-1 with fibrinogen bound to alphaIIbbeta3 and stimulated by platelet-activating factor. J Clin Invest. 1997;100:2085-2093.
    • (1997) J Clin Invest , vol.100 , pp. 2085-2093
    • Weber, C.1    Springer, T.A.2
  • 21
    • 0035412389 scopus 로고    scopus 로고
    • Platelet/polymorphonuclear leukocyte adhesion: A new role for SRC kinases in Mac-1 adhesive function triggered by P-selectin
    • Piccardoni P, Sideri R, Manarini S, et al. Platelet/polymorphonuclear leukocyte adhesion: a new role for SRC kinases in Mac-1 adhesive function triggered by P-selectin. Blood. 2001;98:108-116.
    • (2001) Blood , vol.98 , pp. 108-116
    • Piccardoni, P.1    Sideri, R.2    Manarini, S.3
  • 22
    • 0033622469 scopus 로고    scopus 로고
    • Anti-beta2 glycoprotein I antibodies prevent the de-activation of platelets and sustain their phagocytic clearance
    • Bondanza A, Sabbadini MG, Pellegatta F, et al. Anti-beta2 glycoprotein I antibodies prevent the de-activation of platelets and sustain their phagocytic clearance. J Autoimmun. 2000;15:469-477.
    • (2000) J Autoimmun , vol.15 , pp. 469-477
    • Bondanza, A.1    Sabbadini, M.G.2    Pellegatta, F.3
  • 23
    • 0028690027 scopus 로고
    • Use of recombinant adenovirus for metabolic engineering of mammalian cells
    • Becker TC, Noel RJ, Coats WS, et al. Use of recombinant adenovirus for metabolic engineering of mammalian cells. Methods Cell Biol. 1994;43(pt A):161-189.
    • (1994) Methods Cell Biol , vol.43 , Issue.PART A , pp. 161-189
    • Becker, T.C.1    Noel, R.J.2    Coats, W.S.3
  • 24
    • 0033772857 scopus 로고    scopus 로고
    • Ammonium sulphate precipitation of recombinant adenovirus from culture medium: An easy method to increase the total virus yield
    • Schagen FH, Rademaker HJ, Rabelink MJ, et al. Ammonium sulphate precipitation of recombinant adenovirus from culture medium: an easy method to increase the total virus yield. Gene Ther. 2000;7:1570-1574.
    • (2000) Gene Ther , vol.7 , pp. 1570-1574
    • Schagen, F.H.1    Rademaker, H.J.2    Rabelink, M.J.3
  • 25
    • 0034607136 scopus 로고    scopus 로고
    • Flow cytometric parameters for characterizing platelet activation by measuring P-selectin (CD62) expression: Theoretical consideration and evaluation in thrombin-treated platelet populations
    • Leytin V, Mody M, Semple JW, Garvey B, Freedman J. Flow cytometric parameters for characterizing platelet activation by measuring P-selectin (CD62) expression: theoretical consideration and evaluation in thrombin-treated platelet populations. Biochem Biophys Res Commun. 2000;269:85-90.
    • (2000) Biochem Biophys Res Commun , vol.269 , pp. 85-90
    • Leytin, V.1    Mody, M.2    Semple, J.W.3    Garvey, B.4    Freedman, J.5
  • 26
    • 0036295597 scopus 로고    scopus 로고
    • Thrombopoietin induces P-selectin expression on platelets and subsequent platelet/leukocyte interactions
    • Tibbles HE, Navara CS, Hupke MA, Vassilev AO, Uckun FM. Thrombopoietin induces P-selectin expression on platelets and subsequent platelet/leukocyte interactions. Biochem Biophys Res Commun. 2002;292:987-991.
    • (2002) Biochem Biophys Res Commun , vol.292 , pp. 987-991
    • Tibbles, H.E.1    Navara, C.S.2    Hupke, M.A.3    Vassilev, A.O.4    Uckun, F.M.5
  • 27
    • 0037079740 scopus 로고    scopus 로고
    • Use of blood outgrowth endothelial cells for gene therapy for hemophilia A
    • Lin Y, Chang L, Solovey A, Healey JF, Lollar P, Hebbel RP. Use of blood outgrowth endothelial cells for gene therapy for hemophilia A. Blood. 2002;99:457-462.
    • (2002) Blood , vol.99 , pp. 457-462
    • Lin, Y.1    Chang, L.2    Solovey, A.3    Healey, J.F.4    Lollar, P.5    Hebbel, R.P.6
  • 29
    • 12344303983 scopus 로고    scopus 로고
    • New horizons in the analysis of circulating cell-derived microparticles
    • Horstman LL, Jy W, Jimenez JJ, Bidot C, Ahn YS. New horizons in the analysis of circulating cell-derived microparticles. Keio J Med. 2004;53:210-230.
    • (2004) Keio J Med , vol.53 , pp. 210-230
    • Horstman, L.L.1    Jy, W.2    Jimenez, J.J.3    Bidot, C.4    Ahn, Y.S.5
  • 30
    • 0034651686 scopus 로고    scopus 로고
    • Leukocyte-leukocyte interactions mediated by platelet microparticles under flow
    • Forlow SB, McEver RP, Nollert MU. Leukocyte-leukocyte interactions mediated by platelet microparticles under flow. Blood. 2000;95:1317-1323.
    • (2000) Blood , vol.95 , pp. 1317-1323
    • Forlow, S.B.1    McEver, R.P.2    Nollert, M.U.3
  • 31
    • 25144468784 scopus 로고    scopus 로고
    • Leptin-mediated activation of human platelets: Involvement of a leptin receptor and phosphodiesterase 3A-containing cellular signaling complex
    • Elbatarny HS, Maurice DH. Leptin-mediated activation of human platelets: involvement of a leptin receptor and phosphodiesterase 3A-containing cellular signaling complex. Am J Physiol Endocrinol Metab. 2005;289:E695-702.
    • (2005) Am J Physiol Endocrinol Metab , vol.289
    • Elbatarny, H.S.1    Maurice, D.H.2
  • 32
    • 3242656311 scopus 로고    scopus 로고
    • Cytokine-mediated downregulation of coxsackievirus-adenovirus receptor in endothelial cells
    • Vincent T, Pettersson RF, Crystal RG, Leopold PL. Cytokine-mediated downregulation of coxsackievirus-adenovirus receptor in endothelial cells. J Virol. 2004;78:8047-8058.
    • (2004) J Virol , vol.78 , pp. 8047-8058
    • Vincent, T.1    Pettersson, R.F.2    Crystal, R.G.3    Leopold, P.L.4
  • 33
    • 0347480382 scopus 로고    scopus 로고
    • Intravenous administration of replication-incompetent adenovirus to rhesus monkeys induces thrombocytopenia by increasing in vivo platelet clearance
    • Wolins N, Lozier J, Eggerman TL, Jones E, Aguilar-Cordova E, Vostal JG. Intravenous administration of replication-incompetent adenovirus to rhesus monkeys induces thrombocytopenia by increasing in vivo platelet clearance. Br J Haematol. 2003;123:903-905.
    • (2003) Br J Haematol , vol.123 , pp. 903-905
    • Wolins, N.1    Lozier, J.2    Eggerman, T.L.3    Jones, E.4    Aguilar-Cordova, E.5    Vostal, J.G.6
  • 34
    • 0033039953 scopus 로고    scopus 로고
    • Role of platelet activating factor in development of thrombocytopenia and neutropenia in dogs with endotoxemia
    • Tsuchiya R, Kyotani K, Scott MA, et al. Role of platelet activating factor in development of thrombocytopenia and neutropenia in dogs with endotoxemia. Am J Vet Res. 1999;60:216-221.
    • (1999) Am J Vet Res , vol.60 , pp. 216-221
    • Tsuchiya, R.1    Kyotani, K.2    Scott, M.A.3
  • 35
    • 27144476793 scopus 로고    scopus 로고
    • Activated platelets induce Weibel-Palade-body secretion and leukocyte rolling in vivo: Role of P-selectin
    • Dole VS, Bergmeier W, Mitchell HA, Eichenberger SC, Wagner DD. Activated platelets induce Weibel-Palade-body secretion and leukocyte rolling in vivo: role of P-selectin. Blood. 2005;106:2334-2339.
    • (2005) Blood , vol.106 , pp. 2334-2339
    • Dole, V.S.1    Bergmeier, W.2    Mitchell, H.A.3    Eichenberger, S.C.4    Wagner, D.D.5
  • 36
    • 0036147259 scopus 로고    scopus 로고
    • Adenoviral vectors do not induce, inhibit or potentiate human platelet aggregation
    • Eggermann T, Mondoro T, Lozier J, Vostal J. Adenoviral vectors do not induce, inhibit or potentiate human platelet aggregation. Hum Gene Ther. 2002;13:125-128.
    • (2002) Hum Gene Ther , vol.13 , pp. 125-128
    • Eggermann, T.1    Mondoro, T.2    Lozier, J.3    Vostal, J.4
  • 37
    • 1642603431 scopus 로고    scopus 로고
    • A new role in hemostasis for the adhesion receptor P-selectin
    • Cambien B, Wagner DD. A new role in hemostasis for the adhesion receptor P-selectin. Trends Mol Med. 2004;10:179-186.
    • (2004) Trends Mol Med , vol.10 , pp. 179-186
    • Cambien, B.1    Wagner, D.D.2
  • 38
    • 0037410195 scopus 로고    scopus 로고
    • Platelet apoptosis in stored platelet concentrates and other models
    • Leytin V, Freedman J. Platelet apoptosis in stored platelet concentrates and other models. Transfus Apher Sci. 2003;28:285-295.
    • (2003) Transfus Apher Sci , vol.28 , pp. 285-295
    • Leytin, V.1    Freedman, J.2
  • 39
    • 0037428090 scopus 로고    scopus 로고
    • The clearance mechanism of chilled blood platelets
    • Hoffmeister KM, Felbinger TW, Falet H, et al. The clearance mechanism of chilled blood platelets. Cell. 2003;112:87-97.
    • (2003) Cell , vol.112 , pp. 87-97
    • Hoffmeister, K.M.1    Felbinger, T.W.2    Falet, H.3
  • 41
    • 24044439159 scopus 로고    scopus 로고
    • The macrophage alphaM-beta2 integrin alphaM lectin domain mediates the phagocytosis of chilled platelets
    • Josefsson EC, Gebhard HH, Stossel TP, Hartwig JH, Hoffmeister KM. The macrophage alphaM-beta2 integrin alphaM lectin domain mediates the phagocytosis of chilled platelets. J Biol Chem. 2005;280:18025-18032.
    • (2005) J Biol Chem , vol.280 , pp. 18025-18032
    • Josefsson, E.C.1    Gebhard, H.H.2    Stossel, T.P.3    Hartwig, J.H.4    Hoffmeister, K.M.5
  • 42
    • 0038069517 scopus 로고    scopus 로고
    • The role of capsid-endothelial interaction in the innate immune response to adenovirus vectors
    • Liu Q, Zaiss AK, Colarusso P, Patel K, et al. The role of capsid-endothelial interaction in the innate immune response to adenovirus vectors. Hum Gene Ther. 2003;14:627-643.
    • (2003) Hum Gene Ther , vol.14 , pp. 627-643
    • Liu, Q.1    Zaiss, A.K.2    Colarusso, P.3    Patel, K.4
  • 43
    • 0033756313 scopus 로고    scopus 로고
    • Blood clearance rates of adenovirus type 5 in mice
    • Alemany R, Suzuki K, Curiel DT. Blood clearance rates of adenovirus type 5 in mice. J Gen Virol. 2000;81:2605-2609.
    • (2000) J Gen Virol , vol.81 , pp. 2605-2609
    • Alemany, R.1    Suzuki, K.2    Curiel, D.T.3
  • 44
    • 28844464465 scopus 로고    scopus 로고
    • Rapid Kupffer cell death after intravenous injection of adenovirus vectors
    • Manickan E, Smith JS, Tian J, et al. Rapid Kupffer cell death after intravenous injection of adenovirus vectors. Mol Ther. 2006;13:108-117.
    • (2006) Mol Ther , vol.13 , pp. 108-117
    • Manickan, E.1    Smith, J.S.2    Tian, J.3
  • 45
    • 0042190484 scopus 로고    scopus 로고
    • Chlamydia pneumoniae binds to platelets and triggers P-selectin expression and aggregation: A causal role in cardiovascular disease?
    • Kalvegren H, Majeed M, Bengtsson T. Chlamydia pneumoniae binds to platelets and triggers P-selectin expression and aggregation: a causal role in cardiovascular disease? Arterioscler Thromb Vasc Biol. 2003;23:1677-1683.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1677-1683
    • Kalvegren, H.1    Majeed, M.2    Bengtsson, T.3
  • 46
    • 1542721506 scopus 로고    scopus 로고
    • Platelets as an innate defence mechanism against Schistosoma mansoni infections in mice
    • Stanley RG, Ngaiza JR, Wambayi E, Lewis J, Doenhoff MJ. Platelets as an innate defence mechanism against Schistosoma mansoni infections in mice. Parasite Immunol. 2003;25:467-473.
    • (2003) Parasite Immunol , vol.25 , pp. 467-473
    • Stanley, R.G.1    Ngaiza, J.R.2    Wambayi, E.3    Lewis, J.4    Doenhoff, M.J.5
  • 47
    • 0025313743 scopus 로고
    • Internalization of human immunodeficiency virus type I and other retroviruses by megakaryocytes and platelets
    • Zucker-Franklin D, Seremetis S, Zheng ZY. Internalization of human immunodeficiency virus type I and other retroviruses by megakaryocytes and platelets. Blood. 1990;75:1920-1923.
    • (1990) Blood , vol.75 , pp. 1920-1923
    • Zucker-Franklin, D.1    Seremetis, S.2    Zheng, Z.Y.3
  • 48
    • 33947599732 scopus 로고    scopus 로고
    • Intravascular delivery of adenovirus vectors rapidly targets platelets to the reticuloendothelial system. American Society of Gene Therapy
    • Maryland, May 31-June 4; Abstract
    • Stone D, Ni S, Li Z, Shayakhmetov D, Lieber A. Intravascular delivery of adenovirus vectors rapidly targets platelets to the reticuloendothelial system. American Society of Gene Therapy, 2006 9th Annual Meeting, Maryland, May 31-June 4; Abstract no. 377.
    • (2006) 9th Annual Meeting , Issue.377
    • Stone, D.1    Ni, S.2    Li, Z.3    Shayakhmetov, D.4    Lieber, A.5
  • 49
    • 25144499159 scopus 로고    scopus 로고
    • Adenovirus receptors
    • Zhang Y, Bergelson JM. Adenovirus receptors. J Virol. 2005;79:12125-12131.
    • (2005) J Virol , vol.79 , pp. 12125-12131
    • Zhang, Y.1    Bergelson, J.M.2
  • 50
    • 0029939555 scopus 로고    scopus 로고
    • Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells
    • Huang S, Kamata T, Takada Y, Ruggeri Z M, Nemerow G R. Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells. J Virol. 1996;70:4502-4508.
    • (1996) J Virol , vol.70 , pp. 4502-4508
    • Huang, S.1    Kamata, T.2    Takada, Y.3    Ruggeri, Z.M.4    Nemerow, G.R.5
  • 52
    • 30444436765 scopus 로고    scopus 로고
    • Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-alpha production in vivo
    • Aslam R, Speck ER, Kim M, et al. Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-alpha production in vivo. Blood. 2006;107:637-641.
    • (2006) Blood , vol.107 , pp. 637-641
    • Aslam, R.1    Speck, E.R.2    Kim, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.