Platelet activation and platelet-monocyte aggregate formation contribute to decreased platelet count during acute simian immunodeficiency virus infection in pig-tailed macaques

Journal of Infectious Diseases

Volumn 208, Issue 6, 2013, Pages 874-883

  Metcalf Pate, Kelly A ^a   Lyons, Claire E ^a   Dorsey, Jamie L ^a   Shirk, Erin N ^a   Queen, Suzanne E ^a   Adams, Robert J ^a   Gama, Lucio ^a   Morrell, Craig N ^c   Mankowski, Joseph L ^a,b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

CD16+ monocyte; HIV; macaque; platelet activation; platelet monocyte aggregate; SIV; thrombocytopenia

Indexed keywords

AUTOANTIBODY; CD16 ANTIGEN; CD40 LIGAND; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PADGEM PROTEIN; THROMBOPOIETIN RECEPTOR;

ACUTE DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY DETECTION; CD4 LYMPHOCYTE COUNT; CELL DENSITY; CONFERENCE PAPER; CONTROLLED STUDY; INNATE IMMUNITY; MACACA NEMESTRINA; MALE; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT; THROMBOCYTOPOIESIS; VIRUS LOAD;

CD16+ MONOCYTE; HIV; MACAQUE; PLATELET ACTIVATION; PLATELET-MONOCYTE AGGREGATE; SIV; THROMBOCYTOPENIA;

ANIMALS; AUTOANTIBODIES; BLOOD PLATELETS; CD40 LIGAND; CELL AGGREGATION; DISEASE MODELS, ANIMAL; GENES, MHC CLASS I; IMMUNITY, INNATE; MACACA; MALE; MONOCYTES; P-SELECTIN; PLATELET ACTIVATION; PLATELET COUNT; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; SWINE;

EID: 84883222646     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jit278     Document Type: Conference Paper

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