-
2
-
-
45749132105
-
Somatic FGFR3 and PIK3CA mutations are present in familial seborrhoeic keratoses
-
Hafner C, Vogt T, Landthaler M, et al. Somatic FGFR3 and PIK3CA mutations are present in familial seborrhoeic keratoses. Br J Dermatol. 2008;159:214-217.
-
(2008)
Br J Dermatol.
, vol.159
, pp. 214-217
-
-
Hafner, C.1
Vogt, T.2
Landthaler, M.3
-
4
-
-
78650582977
-
Multiple oncogenic mutations and clonal relationship in spatially distinct benign human epidermal tumors
-
Hafner C, Toll A, Fernandez-Casado A, et al. Multiple oncogenic mutations and clonal relationship in spatially distinct benign human epidermal tumors. Proc Natl Acad Sci U S A. 2010;107:20780-20785.
-
(2010)
Proc Natl Acad Sci USA.
, vol.107
, pp. 20780-20785
-
-
Hafner, C.1
Toll, A.2
Fernandez-Casado, A.3
-
5
-
-
0034820828
-
Phosphatidylinositol 3-kinases in tumor progression
-
Roymans D, Slegers H. Phosphatidylinositol 3-kinases in tumor progression. Eur J Biochem. 2001;268:487-498.
-
(2001)
Eur J Biochem.
, vol.268
, pp. 487-498
-
-
Roymans, D.1
Slegers, H.2
-
6
-
-
34548069945
-
Oncogenic PIK3CA mutations occur in epidermal nevi and seborrheic keratoses with a characteristic mutation pattern
-
Hafner C, Lopez-Knowles E, Luis NM, et al. Oncogenic PIK3CA mutations occur in epidermal nevi and seborrheic keratoses with a characteristic mutation pattern. Proc Natl Acad Sci U S A. 2007;104:13450-13454.
-
(2007)
Proc Natl Acad Sci USA.
, vol.104
, pp. 13450-13454
-
-
Hafner, C.1
Lopez-Knowles, E.2
Luis, N.M.3
-
7
-
-
79955012093
-
A systematic study of gene mutations in urothelial carcinoma; Inactivating mutations in TSC2 and PIK3R1
-
Sjodahl G, Lauss M, Gudjonsson S, et al. A systematic study of gene mutations in urothelial carcinoma; inactivating mutations in TSC2 and PIK3R1. PLoS One. 2011;6:e18583.
-
(2011)
PLoS One.
, vol.6
-
-
Sjodahl, G.1
Lauss, M.2
Gudjonsson, S.3
-
8
-
-
0035886016
-
The phosphatidylinositol 3'-kinase p85alpha gene is an oncogene in human ovarian and colon tumors
-
Philp AJ, Campbell IG, Leet C, et al. The phosphatidylinositol 3'-kinase p85alpha gene is an oncogene in human ovarian and colon tumors. Cancer Res. 2001;61:7426-7429.
-
(2001)
Cancer Res.
, vol.61
, pp. 7426-7429
-
-
Philp, A.J.1
Campbell, I.G.2
Leet, C.3
-
9
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Network CGAR.
-
Network CGAR. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature. 2008;455:1061-1068.
-
(2008)
Nature.
, vol.455
, pp. 1061-1068
-
-
-
10
-
-
0033119157
-
Genomic organization of the human fibroblast growth factor receptor 2 (FGFR2) gene and comparative analysis of the human FGFR gene family
-
Zhang Y, Gorry MC, Post JC, et al. Genomic organization of the human fibroblast growth factor receptor 2 (FGFR2) gene and comparative analysis of the human FGFR gene family. Gene. 1999;230:69-79.
-
(1999)
Gene.
, vol.230
, pp. 69-79
-
-
Zhang, Y.1
Gorry, M.C.2
Post, J.C.3
-
11
-
-
80052974270
-
The receptor tyrosine kinase FGFR2b/KGFR controls early differentiation of human keratinocytes
-
Belleudi F, Purpura V, Torrisi MR. The receptor tyrosine kinase FGFR2b/KGFR controls early differentiation of human keratinocytes. PLoS One. 2011;6:e24194.
-
(2011)
PLoS One.
, vol.6
-
-
Belleudi, F.1
Purpura, V.2
Torrisi, M.R.3
-
12
-
-
34250829395
-
Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes
-
Pollock PM, Gartside MG, Dejeza LC, et al. Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes. Oncogene. 2007;26:7158-7162.
-
(2007)
Oncogene.
, vol.26
, pp. 7158-7162
-
-
Pollock, P.M.1
Gartside, M.G.2
Dejeza, L.C.3
-
13
-
-
47249122523
-
Drug-sensitive FGFR2 mutations in endometrial carcinoma
-
Dutt A, Salvesen HB, Chen TH, et al. Drug-sensitive FGFR2 mutations in endometrial carcinoma. Proc Natl Acad Sci U S A. 2008;105: 8713-8717.
-
(2008)
Proc Natl Acad Sci USA.
, vol.105
, pp. 8713-8717
-
-
Dutt, A.1
Salvesen, H.B.2
Chen, T.H.3
-
14
-
-
34547730818
-
Mutational analysis of EGFR and related signaling pathway genes in lung adenocarcinomas identifies a novel somatic kinase domain mutation in FGFR4
-
Marks JL, McLellan MD, Zakowski MF, et al. Mutational analysis of EGFR and related signaling pathway genes in lung adenocarcinomas identifies a novel somatic kinase domain mutation in FGFR4. PLoS One. 2007;2:e426.
-
(2007)
PLoS One.
, vol.2
-
-
Marks, J.L.1
Mc Lellan, M.D.2
Zakowski, M.F.3
-
15
-
-
0035328856
-
Mutations in fibroblast growth factor receptor 2 and fibroblast growth factor receptor 3 genes associated with human gastric and colorectal cancers
-
Jang JH, Shin KH, Park JG. Mutations in fibroblast growth factor receptor 2 and fibroblast growth factor receptor 3 genes associated with human gastric and colorectal cancers. Cancer Res. 2001;61:3541-3543.
-
(2001)
Cancer Res.
, vol.61
, pp. 3541-3543
-
-
Jang, J.H.1
Shin, K.H.2
Park, J.G.3
-
16
-
-
58749107496
-
Loss-of-function fibroblast growth factor receptor-2 mutations in melanoma
-
Gartside MG, Chen H, Ibrahimi OA, et al. Loss-of-function fibroblast growth factor receptor-2 mutations in melanoma. Mol Cancer Res. 2009; 7:41-54.
-
(2009)
Mol Cancer Res.
, vol.7
, pp. 41-54
-
-
Gartside, M.G.1
Chen, H.2
Ibrahimi, O.A.3
-
17
-
-
17144374478
-
A further mutation of the FGFR2 tyrosine kinase domain in mild Crouzon syndrome
-
de Ravel TJ, Taylor IB, Van Oostveldt AJ, et al. A further mutation of the FGFR2 tyrosine kinase domain in mild Crouzon syndrome. Eur J Hum Genet. 2005;13:503-505.
-
(2005)
Eur J Hum Genet.
, vol.13
, pp. 503-505
-
-
De Ravel, T.J.1
Taylor, I.B.2
Van Oostveldt, A.J.3
-
18
-
-
0029109137
-
Identical mutations in the FGFR2 gene cause both Pfeiffer and Crouzon syndrome phenotypes
-
Rutland P, Pulleyn LJ, Reardon W, et al. Identical mutations in the FGFR2 gene cause both Pfeiffer and Crouzon syndrome phenotypes. Nat Genet. 1995;9:173-176.
-
(1995)
Nat Genet.
, vol.9
, pp. 173-176
-
-
Rutland, P.1
Pulleyn, L.J.2
Reardon, W.3
-
19
-
-
0029089845
-
Crouzon syndrome: Mutations in two spliceoforms of FGFR2 and a common point mutation shared with Jackson-Weiss syndrome
-
Gorry MC, Preston RA, White GJ, et al. Crouzon syndrome: mutations in two spliceoforms of FGFR2 and a common point mutation shared with Jackson-Weiss syndrome. Hum Mol Genet. 1995;4:1387-1390.
-
(1995)
Hum Mol Genet.
, vol.4
, pp. 1387-1390
-
-
Gorry, M.C.1
Preston, R.A.2
White, G.J.3
-
20
-
-
0028113931
-
Jackson-Weiss and Crouzon syndromes are allelic with mutations in fibroblast growth factor receptor 2
-
Jabs EW, Li X, Scott AF, et al. Jackson-Weiss and Crouzon syndromes are allelic with mutations in fibroblast growth factor receptor 2. Nat Genet. 1994;8:275-279.
-
(1994)
Nat Genet.
, vol.8
, pp. 275-279
-
-
Jabs, E.W.1
Li, X.2
Scott, A.F.3
-
21
-
-
0029004086
-
Novel FGFR2 mutations in Crouzon and Jackson-Weiss syndromes show allelic heterogeneity and phenotypic variability
-
Park WJ, Meyers GA, Li X, et al. Novel FGFR2 mutations in Crouzon and Jackson-Weiss syndromes show allelic heterogeneity and phenotypic variability. Hum Mol Genet. 1995;4:1229-1233.
-
(1995)
Hum Mol Genet.
, vol.4
, pp. 1229-1233
-
-
Park, W.J.1
Meyers, G.A.2
Li, X.3
-
22
-
-
0029671080
-
FGFR2 exon IIIa and IIIc mutations in Crouzon, Jackson-Weiss, and Pfeiffer syndromes: Evidence for missense changes, insertions, and a deletion due to alternative RNA splicing
-
Meyers GA, Day D, Goldberg R, et al. FGFR2 exon IIIa and IIIc mutations in Crouzon, Jackson-Weiss, and Pfeiffer syndromes: evidence for missense changes, insertions, and a deletion due to alternative RNA splicing. Am J Hum Genet. 1996;58:491-498.
-
(1996)
Am J Hum Genet.
, vol.58
, pp. 491-498
-
-
Meyers, G.A.1
Day, D.2
Goldberg, R.3
-
23
-
-
0028798546
-
Apert syndrome results from localized mutations of FGFR2 and is allelic with Crouzon syndrome
-
Wilkie AO, Slaney SF, Oldridge M, et al. Apert syndrome results from localized mutations of FGFR2 and is allelic with Crouzon syndrome. Nat Genet. 1995;9:165-172.
-
(1995)
Nat Genet.
, vol.9
, pp. 165-172
-
-
Wilkie, A.O.1
Slaney, S.F.2
Oldridge, M.3
-
24
-
-
15844388219
-
Fibroblast growth factor receptor 2 mutations in Beare-Stevenson cutis gyrata syndrome
-
Przylepa KA, Paznekas W, Zhang M, et al. Fibroblast growth factor receptor 2 mutations in Beare-Stevenson cutis gyrata syndrome. Nat Genet. 1996;13:492-494.
-
(1996)
Nat Genet.
, vol.13
, pp. 492-494
-
-
Przylepa, K.A.1
Paznekas, W.2
Zhang, M.3
-
25
-
-
0032774475
-
Clinical spectrum of fibroblast growth factor receptor mutations
-
Passos-Bueno MR, Wilcox WR, Jabs EW, et al. Clinical spectrum of fibroblast growth factor receptor mutations. Hum Mutat. 1999;14: 115-125.
-
(1999)
Hum Mutat.
, vol.14
, pp. 115-125
-
-
Passos-Bueno, M.R.1
Wilcox, W.R.2
Jabs, E.W.3
-
26
-
-
78149483788
-
FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy
-
Kompier LC, Lurkin I, van der Aa MN, et al. FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy. PLoS One. 2010;5:e13821.
-
(2010)
PLoS One.
, vol.5
-
-
Kompier, L.C.1
Lurkin, I.2
Van Der Aa, M.N.3
-
27
-
-
33845393660
-
FGFR3 mutations in benign skin tumors
-
Hafner C, Vogt T, Hartmann A. FGFR3 mutations in benign skin tumors. Cell Cycle. 2006;5:2723-2728.
-
(2006)
Cell Cycle.
, vol.5
, pp. 2723-2728
-
-
Hafner, C.1
Vogt, T.2
Hartmann, A.3
-
28
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144:646-674.
-
(2011)
Cell.
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
30
-
-
65649147543
-
Braf(V600E) cooperates with Pten loss to induce metastatic melanoma
-
Dankort D, Curley DP, Cartlidge RA, et al. Braf(V600E) cooperates with Pten loss to induce metastatic melanoma. Nat Genet. 2009;41:544-552.
-
(2009)
Nat Genet.
, vol.41
, pp. 544-552
-
-
Dankort, D.1
Curley, D.P.2
Cartlidge, R.A.3
-
31
-
-
23244447037
-
BRAFE600-associated senescence-like cell cycle arrest of human naevi
-
Michaloglou C, Vredeveld LC, Soengas MS, et al. BRAFE600-associated senescence-like cell cycle arrest of human naevi. Nature. 2005;436: 720-724.
-
(2005)
Nature.
, vol.436
, pp. 720-724
-
-
Michaloglou, C.1
Vredeveld, L.C.2
Soengas, M.S.3
-
32
-
-
66149123020
-
Activation of fibroblast growth factor receptor 3 and oncogene-induced senescence in skin tumours
-
Hida Y, Kubo Y, Arase S. Activation of fibroblast growth factor receptor 3 and oncogene-induced senescence in skin tumours. Br J Dermatol. 2009;160:1258-1263.
-
(2009)
Br J Dermatol.
, vol.160
, pp. 1258-1263
-
-
Hida, Y.1
Kubo, Y.2
Arase, S.3
-
33
-
-
78650571948
-
Are oncogenes sufficient to cause human cancer
-
Woodman SE, Mills GB. Are oncogenes sufficient to cause human cancer? Proc Natl Acad Sci U S A. 2010;107:20599-20600.
-
(2010)
Proc Natl Acad Sci USA.
, vol.107
, pp. 20599-20600
-
-
Woodman, S.E.1
Mills, G.B.2
-
34
-
-
77950020483
-
What are the hallmarks of cancer
-
Lazebnik Y. What are the hallmarks of cancer? Nat Rev Cancer. 2010; 10:232-233.
-
(2010)
Nat Rev Cancer.
, vol.10
, pp. 232-233
-
-
Lazebnik, Y.1
-
35
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman PB, Hauschild A, Robert C, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med. 2011;364:2507-2516.
-
(2011)
N Engl J Med.
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
-
36
-
-
9744242038
-
No chromosomal imbalances in seborrheic keratoses detectable by comparative genomic hybridization
-
Hallermann C, Gunawan B, Bertsch HP. No chromosomal imbalances in seborrheic keratoses detectable by comparative genomic hybridization. J Invest Dermatol. 2004;123:1204-1205.
-
(2004)
J Invest Dermatol.
, vol.123
, pp. 1204-1205
-
-
Hallermann, C.1
Gunawan, B.2
Bertsch, H.P.3
-
37
-
-
43649095626
-
Alteration of p53-binding protein 1 expression during skin carcinogenesis: Association with genomic instability
-
Naruke Y, Nakashima M, Suzuki K, et al. Alteration of p53-binding protein 1 expression during skin carcinogenesis: association with genomic instability. Cancer Sci. 2008;99:946-951.
-
(2008)
Cancer Sci.
, vol.99
, pp. 946-951
-
-
Naruke, Y.1
Nakashima, M.2
Suzuki, K.3
-
38
-
-
81455135721
-
HRAS mutation mosaicism causing urothelial cancer and epidermal nevus
-
Hafner C, Toll A, Real FX. HRAS mutation mosaicism causing urothelial cancer and epidermal nevus. N Engl J Med. 2011;365:1940-1942.
-
(2011)
N Engl J Med.
, vol.365
, pp. 1940-1942
-
-
Hafner, C.1
Toll, A.2
Real, F.X.3
-
39
-
-
84860389233
-
Mutations in the epidermal growth factor receptor (EGFR) gene in triple negative breast cancer: Possible implications for targeted therapy
-
Teng YH, Tan WJ, Thike AA, et al. Mutations in the epidermal growth factor receptor (EGFR) gene in triple negative breast cancer: possible implications for targeted therapy. Breast Cancer Res. 2011;13:R35.
-
(2011)
Breast Cancer Res.
, vol.13
-
-
Teng, Y.H.1
Tan, W.J.2
Thike, A.A.3
-
40
-
-
70249092148
-
EGFR-mutations analyse beim nichtkleinzelligen lungenkarzinom
-
Erfahrungen aus der Routinediagnostik
-
Tapia C, Savic S, Bihl M, et al. EGFR-mutations analyse beim nichtkleinzelligen lungenkarzinom. Erfahrungen aus der Routinediagnostik. Pathologe. 2009;30:384-392.
-
(2009)
Pathologe.
, vol.30
, pp. 384-392
-
-
Tapia, C.1
Savic, S.2
Bihl, M.3
-
41
-
-
77958198161
-
Novel epidermal growth factor receptor mutation-specific antibodies for non-small cell lung cancer: Immunohistochemistry as a possible screening method for epidermal growth factor receptor mutations
-
Kato Y, Peled N, Wynes MW, et al. Novel epidermal growth factor receptor mutation-specific antibodies for non-small cell lung cancer: immunohistochemistry as a possible screening method for epidermal growth factor receptor mutations. J Thorac Oncol. 2010;5:1551-1558.
-
(2010)
J Thorac Oncol.
, vol.5
, pp. 1551-1558
-
-
Kato, Y.1
Peled, N.2
Wynes, M.W.3
-
42
-
-
0023429079
-
Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification
-
Wong AJ, Bigner SH, Bigner DD, et al. Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification. Proc Natl Acad Sci U S A. 1987;84: 6899-6903.
-
(1987)
Proc Natl Acad Sci USA.
, vol.84
, pp. 6899-6903
-
-
Wong, A.J.1
Bigner, S.H.2
Bigner, D.D.3
-
43
-
-
54249145112
-
Tumour-associated transcripts and EGFR deletion variants in colorectal cancer in primary tumour, metastases and circulating tumour cells
-
Lankiewicz S, Rother E, Zimmermann S, et al. Tumour-associated transcripts and EGFR deletion variants in colorectal cancer in primary tumour, metastases and circulating tumour cells. Cell Oncol. 2008;30: 463-471.
-
(2008)
Cell Oncol.
, vol.30
, pp. 463-471
-
-
Lankiewicz, S.1
Rother, E.2
Zimmermann, S.3
-
44
-
-
78951472024
-
Epidermal Growth Factor Receptor (EGFR) mutation analysis, gene expression profiling and EGFR protein expression in primary prostate cancer
-
Peraldo-Neia C, Migliardi G,Mello-Grand M, et al. Epidermal Growth Factor Receptor (EGFR) mutation analysis, gene expression profiling and EGFR protein expression in primary prostate cancer. BMC Cancer. 2011;11:31.
-
(2011)
BMC Cancer.
, vol.11
, pp. 31
-
-
Peraldo-Neia, C.1
Migliardi, G.2
Mello-Grand, M.3
-
46
-
-
80052960742
-
Low incidence of EGFR and HRAS mutations in cutaneous squamous cell carcinomas of a German cohort
-
Mauerer A, Herschberger E, Dietmaier W, et al. Low incidence of EGFR and HRAS mutations in cutaneous squamous cell carcinomas of a German cohort. Exp Dermatol. 2011;20:848-850.
-
(2011)
Exp Dermatol.
, vol.20
, pp. 848-850
-
-
Mauerer, A.1
Herschberger, E.2
Dietmaier, W.3
-
47
-
-
4143066760
-
Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways
-
Sordella R, Bell DW, Haber DA, et al. Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways. Science. 2004; 305:1163-1167.
-
(2004)
Science.
, vol.305
, pp. 1163-1167
-
-
Sordella, R.1
Bell, D.W.2
Haber, D.A.3
-
48
-
-
43249096031
-
Structure and clinical relevance of the epidermal growth factor receptor in human cancer
-
Kumar A, Petri ET, Halmos B, et al. Structure and clinical relevance of the epidermal growth factor receptor in human cancer. J Clin Oncol. 2008;26:1742-1751.
-
(2008)
J Clin Oncol.
, vol.26
, pp. 1742-1751
-
-
Kumar, A.1
Petri, E.T.2
Halmos, B.3
-
49
-
-
33947594129
-
Hyperactive Ras in developmental disorders and cancer
-
Schubbert S, Shannon K, Bollag G. Hyperactive Ras in developmental disorders and cancer. Nat Rev Cancer. 2007;7:295-308.
-
(2007)
Nat Rev Cancer.
, vol.7
, pp. 295-308
-
-
Schubbert, S.1
Shannon, K.2
Bollag, G.3
-
50
-
-
0029125820
-
K-ras mutation and pancreatic adenocarcinoma
-
Caldas C, Kern SE. K-ras mutation and pancreatic adenocarcinoma. Int J Pancreatol. 1995;18:1-6.
-
(1995)
Int J Pancreatol.
, vol.18
, pp. 1-6
-
-
Caldas, C.1
Kern, S.E.2
-
51
-
-
79953786463
-
Genetic mutations of p53 and k-ras in gastric carcinoma patients from Hunan China
-
Chen HC, Chen HJ, Khan MA, et al. Genetic mutations of p53 and k-ras in gastric carcinoma patients from Hunan, China. Tumour Biol. 2011;32: 367-373.
-
(2011)
Tumour Biol.
, vol.32
, pp. 367-373
-
-
Chen, H.C.1
Chen, H.J.2
Khan, M.A.3
-
52
-
-
0034518430
-
K-ras oncogene mutation in cancer and precancerous lesions of the gallbladder
-
Kim SW, Her KH, Jang JY, et al. K-ras oncogene mutation in cancer and precancerous lesions of the gallbladder. J Surg Oncol. 2000;75:246-251.
-
(2000)
J Surg Oncol.
, vol.75
, pp. 246-251
-
-
Kim, S.W.1
Her, K.H.2
Jang, J.Y.3
-
53
-
-
33846641709
-
High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer
-
Krypuy M, Newnham GM, Thomas DM, et al. High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer. BMC Cancer. 2006;6:295.
-
(2006)
BMC Cancer.
, vol.6
, pp. 295
-
-
Krypuy, M.1
Newnham, G.M.2
Thomas, D.M.3
-
54
-
-
69949129964
-
Ras pathway activation in hepatocellular carcinoma and anti-tumoral effect of combined sorafenib and rapamycin in vivo
-
Newell P, Toffanin S, Villanueva A, et al. Ras pathway activation in hepatocellular carcinoma and anti-tumoral effect of combined sorafenib and rapamycin in vivo. J Hepatol. 2009;51:725-733.
-
(2009)
J Hepatol.
, vol.51
, pp. 725-733
-
-
Newell, P.1
Toffanin, S.2
Villanueva, A.3
-
55
-
-
0027712025
-
H-ras gene mutations in salivary gland pleomorphic adenomas
-
Milasin J, Pujic N, Dedovic N, et al. H-ras gene mutations in salivary gland pleomorphic adenomas. Int J Oral Maxillofac Surg. 1993;22: 359-361.
-
(1993)
Int J Oral Maxillofac Surg.
, vol.22
, pp. 359-361
-
-
Milasin, J.1
Pujic, N.2
Dedovic, N.3
-
56
-
-
0024413216
-
Oncogene activation in human benign tumors of the skin (keratoacanthomas): Is HRAS involved in differentiation as well as proliferation
-
Corominas M, Kamino H, Leon J, et al. Oncogene activation in human benign tumors of the skin (keratoacanthomas): is HRAS involved in differentiation as well as proliferation? Proc Natl Acad Sci U S A. 1989;86:6372-6376.
-
(1989)
Proc Natl Acad Sci USA.
, vol.86
, pp. 6372-6376
-
-
Corominas, M.1
Kamino, H.2
Leon, J.3
-
58
-
-
73349116574
-
BRAF, NRAS and HRAS mutations in spitzoid tumours and their possible pathogenetic significance
-
Da Forno PD, Pringle JH, Fletcher A, et al. BRAF, NRAS and HRAS mutations in spitzoid tumours and their possible pathogenetic significance. Br J Dermatol. 2009;161:364-372.
-
(2009)
Br J Dermatol.
, vol.161
, pp. 364-372
-
-
Da Forno, P.D.1
Pringle, J.H.2
Fletcher, A.3
-
59
-
-
84864078171
-
Keratinocytic epidermal nevi are associated with mosaic RAS mutations
-
Hafner C, Toll A, Gantner S, et al. Keratinocytic epidermal nevi are associated with mosaic RAS mutations. J Med Genet. 2012;49:249-253.
-
(2012)
J Med Genet.
, vol.49
, pp. 249-253
-
-
Hafner, C.1
Toll, A.2
Gantner, S.3
-
60
-
-
78649620521
-
Mosaicism for oncogenic G12D KRAS mutation associated with epidermal nevus, polycystic kidneys and rhabdomyosarcoma
-
Bourdeaut F, Herault A, Gentien D, et al. Mosaicism for oncogenic G12D KRAS mutation associated with epidermal nevus, polycystic kidneys and rhabdomyosarcoma. J Med Genet. 2010;47:859-862.
-
(2010)
J Med Genet.
, vol.47
, pp. 859-862
-
-
Bourdeaut, F.1
Herault, A.2
Gentien, D.3
-
61
-
-
84862982298
-
Postzygotic HRAS and KRAS mutations cause nevus sebaceous and Schimmelpenning syndrome
-
doi : 10.1038/ng.2316
-
Groesser L, Herschberger E, Ruetten A, et al. Postzygotic HRAS and KRAS mutations cause nevus sebaceous and Schimmelpenning syndrome. Nat Genet. 2012;44:783-787. doi : 10.1038/ng.2316.
-
(2012)
Nat Genet.
, vol.44
, pp. 783-783
-
-
Groesser, L.1
Herschberger, E.2
Ruetten, A.3
-
62
-
-
0027522545
-
High mutation frequency in ras genes of skin tumors isolated from DNA repair deficient xeroderma pigmentosum patients
-
Daya-Grosjean L, Robert C, Drougard C, et al. High mutation frequency in ras genes of skin tumors isolated from DNA repair deficient xeroderma pigmentosum patients. Cancer Res. 1993;53:1625-1629.
-
(1993)
Cancer Res.
, vol.53
, pp. 1625-1629
-
-
Daya-Grosjean, L.1
Robert, C.2
Drougard, C.3
-
63
-
-
0029118414
-
Fibroblast growth factors in mammalian development
-
Yamaguchi TP, Rossant J. Fibroblast growth factors in mammalian development. Curr Opin Genet Dev. 1995;5:485-491.
-
(1995)
Curr Opin Genet Dev.
, vol.5
, pp. 485-491
-
-
Yamaguchi, T.P.1
Rossant, J.2
-
64
-
-
0031600117
-
The heparan sulfate-fibroblast growth factor family: Diversity of structure and function
-
McKeehan WL, Wang F, Kan M. The heparan sulfate-fibroblast growth factor family: diversity of structure and function. Prog Nucleic Acid Res Mol Biol. 1998;59:135-176.
-
(1998)
Prog Nucleic Acid Res Mol Biol.
, vol.59
, pp. 135-176
-
-
McKeehan, W.L.1
Wang, F.2
Kan, M.3
-
65
-
-
0032841519
-
Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas
-
Cappellen D, De Oliveira C, Ricol D, et al. Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas. Nat Genet. 1999;23: 18-20.
-
(1999)
Nat Genet.
, vol.23
, pp. 18-20
-
-
Cappellen, D.1
De Oliveira, C.2
Ricol, D.3
-
66
-
-
34250637875
-
FGFR3 mutations in epidermal nevi and seborrheic keratoses: Lessons from urothelium and skin
-
Hafner C, Hartmann A, Vogt T. FGFR3 mutations in epidermal nevi and seborrheic keratoses: lessons from urothelium and skin. J Invest Dermatol. 2007;127:1572-1573.
-
(2007)
J Invest Dermatol.
, vol.127
, pp. 1572-1573
-
-
Hafner, C.1
Hartmann, A.2
Vogt, T.3
-
67
-
-
33746754183
-
Mosaicism of activating FGFR3 mutations in human skin causes epidermal nevi
-
Hafner C, van Oers JM, Vogt T, et al. Mosaicism of activating FGFR3 mutations in human skin causes epidermal nevi. J Clin Invest. 2006;116: 2201-2207.
-
(2006)
J Clin Invest.
, vol.116
, pp. 2201-2207
-
-
Hafner, C.1
Van Oers, J.M.2
Vogt, T.3
-
68
-
-
20944433657
-
Activating mutations of the tyrosine kinase receptor FGFR3 are associated with benign skin tumors in mice and humans
-
Logie A, Dunois-Larde C, Rosty C, et al. Activating mutations of the tyrosine kinase receptor FGFR3 are associated with benign skin tumors in mice and humans. Hum Mol Genet. 2005;14:1153-1160.
-
(2005)
Hum Mol Genet.
, vol.14
, pp. 1153-1160
-
-
Logie, A.1
Dunois-Larde, C.2
Rosty, C.3
-
69
-
-
34447556773
-
Spectrum of FGFR3 mutations in multiple intraindividual seborrheic keratoses
-
Hafner C, Hartmann A, Real FX, et al. Spectrum of FGFR3 mutations in multiple intraindividual seborrheic keratoses. J Invest Dermatol. 2007; 127:1883-1885.
-
(2007)
J Invest Dermatol.
, vol.127
, pp. 1883-1885
-
-
Hafner, C.1
Hartmann, A.2
Real, F.X.3
-
70
-
-
77953363228
-
FGFR3 mutation affects cell growth, apoptosis and attachment in keratinocytes
-
Hafner C, Di Martino E, Pitt E, et al. FGFR3 mutation affects cell growth, apoptosis and attachment in keratinocytes. Exp Cell Res. 2010; 316:2008-2016.
-
(2010)
Exp Cell Res.
, vol.316
, pp. 2008-2016
-
-
Hafner, C.1
Di Martino, E.2
Pitt, E.3
-
71
-
-
33750039697
-
High frequency of FGFR3 mutations in adenoid seborrheic keratoses
-
Hafner C, van Oers JM, Hartmann A, et al. High frequency of FGFR3 mutations in adenoid seborrheic keratoses. J Invest Dermatol. 2006;126: 2404-2407.
-
(2006)
J Invest Dermatol.
, vol.126
, pp. 2404-2407
-
-
Hafner, C.1
Van Oers, J.M.2
Hartmann, A.3
-
72
-
-
34447576555
-
FGFR3 mutations in seborrheic keratoses are already present in flat lesions and associated with age and localization
-
Hafner C, Hartmann A, van Oers JM, et al. FGFR3 mutations in seborrheic keratoses are already present in flat lesions and associated with age and localization. Mod Pathol. 2007;20:895-903.
-
(2007)
Mod Pathol.
, vol.20
, pp. 895-903
-
-
Hafner, C.1
Hartmann, A.2
Van Oers, J.M.3
|