-
1
-
-
78650582977
-
Multiple oncogenic mutations and clonal relationship in spatially distinct benign human epidermal tumors
-
Hafner C, et al. (2010) Multiple oncogenic mutations and clonal relationship in spatially distinct benign human epidermal tumors. Proc Natl Acad Sci USA 107:20780-20785.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 20780-20785
-
-
Hafner, C.1
-
2
-
-
77954242901
-
FGFR3 mutations and the skin: Report of a patient with a FGFR3 gene mutation, acanthosis nigricans, hypochondroplasia and hyperinsulinemia and review of the literature
-
Blomberg M, Jeppesen EM, Skovby F, Benfeldt E (2010) FGFR3 mutations and the skin: Report of a patient with a FGFR3 gene mutation, acanthosis nigricans, hypochondroplasia and hyperinsulinemia and review of the literature. Dermatology 220:297-305.
-
(2010)
Dermatology
, vol.220
, pp. 297-305
-
-
Blomberg, M.1
Jeppesen, E.M.2
Skovby, F.3
Benfeldt, E.4
-
3
-
-
70249105783
-
No mutations of FGFR3 in normal urothelium in the vicinity of urothelial carcinoma of the bladder harbouring activating FGFR3 mutations in patients with bladder cancer
-
Otto W, et al. (2009) No mutations of FGFR3 in normal urothelium in the vicinity of urothelial carcinoma of the bladder harbouring activating FGFR3 mutations in patients with bladder cancer. Int J Cancer 125:2205-2208.
-
(2009)
Int J Cancer
, vol.125
, pp. 2205-2208
-
-
Otto, W.1
-
4
-
-
67349105009
-
FGFR3 mutations in prostate cancer: Association with low-grade tumors
-
Hernández S, et al. (2009) FGFR3 mutations in prostate cancer: Association with low-grade tumors. Mod Pathol 22:848-856.
-
(2009)
Mod Pathol
, vol.22
, pp. 848-856
-
-
Hernández, S.1
-
6
-
-
70449995469
-
Identifying genotype-dependent efficacy of single and combined PI3K- andMAPK-pathway inhibition in cancer
-
Sos ML, et al. (2009) Identifying genotype-dependent efficacy of single and combined PI3K- andMAPK-pathway inhibition in cancer. ProcNatl Acad SciUSA 106:18351-18356.
-
(2009)
ProcNatl Acad SciUSA
, vol.106
, pp. 18351-18356
-
-
Sos, M.L.1
-
7
-
-
72949096792
-
Senescence in tumours: Evidence from mice and humans
-
Collado M, Serrano M (2010) Senescence in tumours: Evidence from mice and humans. Nat Rev Cancer 10:51-57.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 51-57
-
-
Collado, M.1
Serrano, M.2
-
8
-
-
70049104593
-
Genetics and genomics of melanoma
-
Ghosh P, Chin L (2009) Genetics and genomics of melanoma. Expert Rev Dermatol 4:131-143.
-
(2009)
Expert Rev Dermatol
, vol.4
, pp. 131-143
-
-
Ghosh, P.1
Chin, L.2
-
9
-
-
63249105225
-
Oncogenic Braf induces melanocyte senescence and melanoma in mice
-
Dhomen N, et al. (2009) Oncogenic Braf induces melanocyte senescence and melanoma in mice. Cancer Cell 15:294-303.
-
(2009)
Cancer Cell
, vol.15
, pp. 294-303
-
-
Dhomen, N.1
-
10
-
-
65649147543
-
Braf(V600E) cooperates with Pten loss to induce metastatic melanoma
-
Dankort D, et al. (2009) Braf(V600E) cooperates with Pten loss to induce metastatic melanoma. Nat Genet 41:544-552.
-
(2009)
Nat Genet
, vol.41
, pp. 544-552
-
-
Dankort, D.1
-
11
-
-
67749122122
-
Targeting PI3K signalling in cancer: Opportunities, challenges and limitations
-
Engelman JA (2009) Targeting PI3K signalling in cancer: Opportunities, challenges and limitations. Nat Rev Cancer 9:550-562.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 550-562
-
-
Engelman, J.A.1
-
12
-
-
77954235111
-
Targeting the mitogenactivated protein kinase pathway: Physiological feedback and drug response
-
Pratilas CA, Solit DB (2010) Targeting the mitogenactivated protein kinase pathway: Physiological feedback and drug response. Clin Cancer Res 16:3329-3334.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3329-3334
-
-
Pratilas, C.A.1
Solit, D.B.2
-
13
-
-
70349659643
-
A positive FGFR3/FOXN1 feedback loop underlies benign skin keratosis versus squamous cell carcinoma formation in humans
-
Mandinova A, et al. (2009) A positive FGFR3/FOXN1 feedback loop underlies benign skin keratosis versus squamous cell carcinoma formation in humans. J Clin Invest 119:3127-3137.
-
(2009)
J Clin Invest
, vol.119
, pp. 3127-3137
-
-
Mandinova, A.1
-
14
-
-
77953774777
-
The origins of urothelial carcinoma
-
Cheng L, et al. (2010) The origins of urothelial carcinoma. Expert Rev Anticancer Ther 10:865-880.
-
(2010)
Expert Rev Anticancer Ther
, vol.10
, pp. 865-880
-
-
Cheng, L.1
-
15
-
-
25444467767
-
Urothelial tumorigenesis: A tale of divergent pathways
-
Wu XR (2005) Urothelial tumorigenesis: A tale of divergent pathways. Nat Rev Cancer 5:713-725.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 713-725
-
-
Wu, X.R.1
-
16
-
-
0344155279
-
Metastasis of benign tumor cells in tuberous sclerosis complex
-
Henske EP (2003) Metastasis of benign tumor cells in tuberous sclerosis complex. Genes Chromosomes Cancer 38:376-381.
-
(2003)
Genes Chromosomes Cancer
, vol.38
, pp. 376-381
-
-
Henske, E.P.1
-
17
-
-
74949090816
-
The evolutionarily conserved TSC/Rheb pathway activates Notch in tuberous sclerosis complex and Drosophila external sensory organ development
-
Karbowniczek M, et al. (2010) The evolutionarily conserved TSC/Rheb pathway activates Notch in tuberous sclerosis complex and Drosophila external sensory organ development. J Clin Invest 120:93-102.
-
(2010)
J Clin Invest
, vol.120
, pp. 93-102
-
-
Karbowniczek, M.1
|