Correlation between plasma, synovial fluid and articular cartilage Interleukin-18 with radiographic severity in 33 patients with osteoarthritis of the knee

Clinical and Experimental Medicine

Volumn 14, Issue 3, 2014, Pages 297-304

  Wang, Youhua ^a   Xu, Dawei ^b   Long, Long ^b   Deng, Xiaolong ^b   Tao, Ran ^b   Huang, Guicheng ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b NANTONG UNIVERSITY   (China)

Author keywords

Cartilage; Interleukin 18 (IL 18); Osteoarthritis (OA); Plasma; Synovial fluid

Indexed keywords

INTERLEUKIN 18; INTERLEUKIN 18 PROTEIN, HUMAN;

AGED; ARTICULAR CARTILAGE; CHEMISTRY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMAN; KNEE OSTEOARTHRITIS; MALE; MIDDLE AGED; PATHOLOGY; PLASMA; RADIOGRAPHY; SYNOVIAL FLUID;

AGED; CARTILAGE, ARTICULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; INTERLEUKIN-18; MALE; MIDDLE AGED; OSTEOARTHRITIS, KNEE; PLASMA; SYNOVIAL FLUID;

EID: 84905103639     PISSN: 15918890     EISSN: 15919528     Source Type: Journal    
DOI: 10.1007/s10238-013-0251-8     Document Type: Article

References (32)

1. Palmieri B, Lodi D, Capone S (2010) Osteoarthritis and degenerative joint disease: local treatment options update. Acta Biomed 81:94-100
2. Bijlsma JW, Berenbaum F, Lafeber FP (2011) Osteoarthritis: an update with relevance for clinical practice. Lancet 377:2115-2126
3. Mehta VB, Hart J, Wewers MD (2001) ATP-stimulated release of interleukin (IL)-1beta and IL-18 requires priming by lipopolysaccharide and is independent of caspase-1 cleavage. J Biol Chem 276:3820-3826
4. Nakanishi K, Yoshimoto T, Tsutsui H, Okamura H (2001) Interleukin-18 regulates both Th1 and Th2 responses. Annu Rev Immunol 19:423-474 (Pubitemid 32368042)
5. Olee T, Hashimoto S, Quach J, Lotz M (1999) IL-18 is produced by articular chondrocytes and induces proinflammatory and catabolic responses. J Immunol 162:1096-1100 (Pubitemid 29035439)
6. Wittmann M, Purwar R, Hartmann C, Gutzmer R, Werfel T (2005) Human keratinocytes respond to interleukin-18: implication for the course of chronic inflammatory skin diseases. J Invest Dermatol 124:1225-1233 (Pubitemid 40847410)
7. Udagawa N, Horwood NJ, Elliott J, Mackay A, Owens J, Okamura H, Kurimoto M, Chambers TJ, Martin TJ, Gillespie MT (1997) Interleukin-18 (interferon-gamma-inducing factor) is produced by osteoblasts and acts via granulocyte/macrophage colony-stimulating factor and not via interferon-gamma to inhibit osteoclast formation. J Exp Med 185:1005-1012 (Pubitemid 27136793)
8. Wei XQ, Leung BP, Arthur HM, McInnes IB, Liew FY (2001) Reduced incidence and severity of collagen-induced arthritis in mice lacking IL-18. J Immunol 166:517-521 (Pubitemid 32038471)
9. Hung J, McQuillan BM, Chapman CM, Thompson PL, Beilby JP (2005) Elevated interleukin-18 levels are associated with the metabolic syndrome independent of obesity and insulin resistance. Arterioscler Thromb Vasc Biol 25:1268-1273 (Pubitemid 40776620)
10. Dai SM, Shan ZZ, Xu H, Nishioka K (2007) Cellular targets of interleukin-18 in rheumatoid arthritis. Ann Rheum Dis 66:1411-1418 (Pubitemid 350032645)
11. Akira S (2000) The role of IL-18 in innate immunity. Curr Opin Immunol 12:59-63
12. Kawase Y, Hoshino T, Yokota K, Kuzuhara A, Kirii Y, Nishiwaki E, Maeda Y, Takeda J, Okamoto M, Kato S, Imaizumi T, Aizawa H, Yoshino K (2003) Exacerbated and prolonged allergic and non-allergic inflammatory cutaneous reaction in mice with targeted interleukin-18 expression in the skin. J Invest Dermatol 121:502-509 (Pubitemid 37072261)
13. Okamoto M, Kato S, Oizumi K, Kinoshita M, Inoue Y, Hoshino K, Akira S, McKenzie AN, Young HA, Hoshino T (2002) Interleukin 18 (IL-18) in synergy with IL-2 induces lethal lung injury in mice: a potential role for cytokines, chemokines, and natural killer cells in the pathogenesis of interstitial pneumonia. Blood 99:1289-1298 (Pubitemid 34547083)
14. Petrovic-Rackov L, Pejnovic N (2006) Clinical significance of IL-18, IL-15, IL-12 and TNF-alpha measurement in rheumatoid arthritis. Clin Rheumatol 25:448-452 (Pubitemid 44137612)
15. Futani H, Okayama A, Matsui K, Kashiwamura S, Sasaki T, Hada T, Nakanishi K, Tateishi H, Maruo S, Okamura H (2002) Relation between interleukin-18 and PGE2 in synovial fluid of osteoarthritis: a potential therapeutic target of cartilage degradation. J Immunother 25(Suppl 1):S61-S64 (Pubitemid 34260759)
16. Takei S, Hoshino T, Matsunaga K, Sakazaki Y, Sawada M, Oda H, Takenaka S, Imaoka H, Kinoshita T, Honda S, Ida H, Fukuda TA, Aizawa H (2011) Soluble interleukin-18 receptor complex is a novel biomarker in rheumatoid arthritis. Arthritis Res Ther 13:R52
17. Dai SM, Shan ZZ, Nishioka K, Yudoh K (2005) Implication of interleukin 18 in production of matrix metalloproteinases in articular chondrocytes in arthritis: direct effect on chondrocytes may not be pivotal. Ann Rheum Dis 64:735-742 (Pubitemid 40559301)
18. Plater-Zyberk C, Joosten LA, Helsen MM, Sattonnet-Roche P, Siegfried C, Alouani S, van De Loo FA, Graber P, Aloni S, Cirillo R, Lubberts E, Dinarello CA, van Den Berg WB, Chvatchko Y (2001) Therapeutic effect of neutralizing endogenous IL-18 activity in the collagen-induced model of arthritis. J Clin Invest 108:1825-1832 (Pubitemid 34015128)
19. Joosten LA, Radstake TR, Lubberts E, van den Bersselaar LA, van Riel PL, van Lent PL, Barrera P, van den Berg WB (2003) Association of interleukin-18 expression with enhanced levels of both interleukin-1 beta and tumor necrosis factor alpha in knee synovial tissue of patients with rheumatoid arthritis. Arthritis Rheum 48:339-347 (Pubitemid 36278001)
20. Peng CZ, Cao JM, Xiao T, Peng C, Yang HB, Chen X, Fang JZ (2006) Concentration of IL-18 and PGE2 in synovial fluid in patients with osteoarthritis and its significance. Zhong Nan Da Xue Xue Bao Yi Xue Ban 31:862-865 (Pubitemid 46113720)
21. Fu Z, Liu P, Yang D, Wang F, Yuan L, Lin Z, Jiang J (2012) Interleukin-18-induced inflammatory responses in synoviocytes and chondrocytes from osteoarthritic patients. Int J Mol Med 30:805-810
22. Kellgren JH, Lawrence JS (1957) Radiological assessment of osteo-arthrosis. Ann Rheum Dis 16:494-502
23. Pelletier JP, Lascau-Coman V, Jovanovic D, Fernandes JC, Manning P, Connor JR, Currie MG, Martel-Pelletier J (1999) Selective inhibition of inducible nitric oxide synthase in experimental osteoarthritis is associated with reduction in tissue levels of catabolic factors. J Rheumatol 26:2002-2014 (Pubitemid 30007071)
24. Rooney T, Murphy E, Benito M, Roux-Lombard P, FitzGerald O, Dayer JM, Bresnihan B (2004) Synovial tissue interleukin-18 expression and the response to treatment in patients with inflammatory arthritis. Ann Rheum Dis 63:1393-1398 (Pubitemid 39433941)
25. Inoue H, Hiraoka K, Hoshino T, Okamoto M, Iwanaga T, Zenmyo M, Shoda T, Aizawa H, Nagata K (2008) High levels of serum IL-18 promote cartilage loss through suppression of aggrecan synthesis. Bone 42:1102-1110
26. Kinds MB, Welsing PM, Vignon EP, Bijlsma JW, Viergever MA, Marijnissen AC, Lafeber FP (2011) A systematic review of the association between radiographic and clinical osteoarthritis of hip and knee. Osteoarthritis Cartilage 19:768-778
27. van der Sluijs JA, Geesink RG, van der Linden AJ, Bulstra SK, Kuyer R, Drukker J (1992) The reliability of the Mankin score for osteoarthritis. J Orthop Res 10:58-61
28. DeGroot J, Bank RA, Tchetverikov I, Verzijl N, TeKoppele JM (2002) Molecular markers for osteoarthritis: the road ahead. Curr Opin Rheumatol 14:585-589 (Pubitemid 34953800)
29. van Spil WE, DeGroot J, Lems WF, Oostveen JC, Lafeber FP (2010) Serum and urinary biochemical markers for knee and hiposteoarthritis: a systematic review applying the consensus BIPED criteria. Osteoarthritis Cartilage 18:605-612
30. de Lange-Brokaar BJ, Ioan-Facsinay A, van Osch GJ, Zuurmond AM, Schoones J, Toes RE, Huizinga TW, Kloppenburg M (2012) Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review. Osteoarthritis Cartilage 20:1484-1499
31. Neidhart M, Hauser N, Paulsson M, DiCesare PE, Michel BA, Hauselmann HJ (1997) Small fragments of cartilage oligomeric matrix protein in synovial fluid and serum as markers for cartilage degradation. Br J Rheumatol 36:1151-1160
32. Kinds MB, Marijnissen AC, Viergever MA, Emans PJ, Lafeber FP, Welsing PM (2013) Identifying phenotypes of knee osteoarthritis by separate quantitative radiographic features may improve patient selection for more targeted treatment. J Rheumatol 40:891-902