Mouse monoclonal antibodies to transient receptor potential ankyrin 1 act as antagonists of multiple modes of channel activation

Journal of Pharmacology and Experimental Therapeutics

Volumn 350, Issue 2, 2014, Pages 223-231

  Lee, Ki Jeong ^a   Wang, Weiya ^a   Padaki, Rupa ^a   Bi, Vivian ^a   Plewa, Cherylene A ^a   Gavva, Narender R ^a  

^a AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLYL ISOTHIOCYANATE; CALCIUM ION; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 2B10; MONOCLONAL ANTIBODY 2D1; TRANSIENT RECEPTOR POTENTIAL ANKYRIN 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CALCIUM TRANSPORT; CHO CELL LINE; COLD; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENCY; FLOW CYTOMETRY; HYBRIDOMA; IC 50; MOUSE; NONHUMAN; OSMOSIS; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PURIFICATION; U2OS CELL LINE;

ALDEHYDES; AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; CALCIUM; CALCIUM CHANNELS; CHO CELLS; CRICETULUS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; TRANSIENT RECEPTOR POTENTIAL CHANNELS;

EID: 84905060770     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.114.215574     Document Type: Article

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