Antiallergic and antiasthmatic effects of a novel enhydrazinone ester (CEE-1): Inhibition of activation of both mast cells and eosinophils

Journal of Pharmacology and Experimental Therapeutics

Volumn 350, Issue 2, 2014, Pages 444-454

  Ezeamuzie, Charles I ^a   El Hashim, Ahmed Z ^a   Renno, Waleed M ^a   Edafiogho, Ivan O ^b  

^a KUWAIT UNIVERSITY   (Kuwait)

^b UNIVERSITY OF SAINT JOSEPH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; CLEMASTINE; DEXAMETHASONE; ESTER DERIVATIVE; ETHYL 4 PHENYLHYDRAZINOCYCLOHEX 3 EN 2 OXO 6 PHENYL 1 OATE; IMMUNOGLOBULIN E; LEUKOTRIENE C4; METHACHOLINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIALLERGIC EFFECT; ANTIASTHMATIC EFFECT; ARTICLE; BRONCHITIS; CALCIUM CELL LEVEL; CELL ACTIVATION; CELL VIABILITY; CONTROLLED STUDY; DEGRANULATION; DRUG ACTIVITY; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; ENZYME PHOSPHORYLATION; EOSINOPHIL; EOSINOPHIL COUNT; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA CELL; LUNG LAVAGE; LYMPHOCYTE; LYMPHOCYTE COUNT; MALE; MAST CELL; MOUSE; NEUTROPHIL COUNT; NONHUMAN; NORMAL HUMAN; PASSIVE SKIN ANAPHYLAXIS; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN SECRETION; RAT; RESPIRATORY TRACT ALLERGY;

ADULT; ANIMALS; ANTI-ALLERGIC AGENTS; ANTI-ASTHMATIC AGENTS; CALCIUM; CELL SURVIVAL; CELLS, CULTURED; CYCLOHEXANECARBOXYLIC ACIDS; EOSINOPHILS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; IMMUNOGLOBULIN E; LEUKOTRIENE C4; MALE; MAST CELLS; MICE; PASSIVE CUTANEOUS ANAPHYLAXIS; PHENYLHYDRAZINES; PHOSPHORYLATION; RATS;

EID: 84905046026     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.114.213751     Document Type: Article

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