Effects of some anti-asthma drugs on human eosinophil superoxide anions release and degranulation

International Archives of Allergy and Immunology

Volumn 115, Issue 2, 1998, Pages 162-168

  Ezeamuzie, Charles I ^a   Al Hage, Mary ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

Author keywords

Anti asthma drugs; Asthma; Degranulation; Eosinophils; Superoxide anions

Indexed keywords

ANTIASTHMATIC AGENT; AZELASTINE; COMPLEMENT COMPONENT C5A; CROMOGLYCATE DISODIUM; DENBUFYLLINE; DEXAMETHASONE; FORMYLMETHIONYLLEUCYLPHENYLALANINE; INTERLEUKIN 5; KETOTIFEN; PEROXIDASE; SALBUTAMOL; SALMETEROL; SUPEROXIDE; THEOPHYLLINE; THROMBOCYTE ACTIVATING FACTOR;

ARTICLE; CELL GRANULE; CELL SECRETION; CONTROLLED STUDY; DEGRANULATION; DOSE RESPONSE; DRUG EFFECT; EOSINOPHIL; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ANTI-ASTHMATIC AGENTS; CELL DEGRANULATION; COMPLEMENT C5A; DOSE-RESPONSE RELATIONSHIP, DRUG; EOSINOPHIL PEROXIDASE; EOSINOPHILS; HUMANS; INTERLEUKIN-5; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; PEROXIDASES; PLATELET ACTIVATING FACTOR; SUPEROXIDES;

EID: 0031984726     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000023897     Document Type: Article

References (27)

1. Frigas E, Gleich GJ: The eosinophil and the pathophysiology of asthma. J Allergy Clin Immunol 1986;77:527-537.
2. Wardlaw AJ, Dunnette S, Gleich GJ, Collins JV, Kay AB: Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. Am Rev Respir Dis 1988;137:62-69.
3. Barnes PJ: New concepts in pathogenesis of bronchial hyperresponsiveness and asthma. J Allergy Clin Immunol 1989;83:1013-1026.
4. Motijima S, Frigas E, Loegering DA, Gleich GT: Toxicity of eosinophil proteins for guinea pig tracheal epithelium in vitro. Am Rev Respir Dis 1989;139:801-805.
5. Laitinen LA, Heins M, Laitinen A, Kava T, Haahtela T: Damage of the airway epithelium and bronchial reactivity in patients with asthma. Am Rev Respir Dis 1985;131:599-606.
6. Braun RK, Franchini M, Erard F, Rihs S, De Vries IJM, Blaser K, Hansel TT, Walker C: Human peripheral blood eosinophils produce and release interleukin-8 on stimulation with calcium ionophore. Eur J Immunol 1993;23:956-960.
7. Martin LB, Kita H, Leiferman KM, Gleich GJ: Eosinophils in allergy: Role in disease, degranulation and cytokines. Int Arch Allergy Immunol 1996;109:207-215.
8. Pedersen B, Dahl R, Larsen BB, Venge P: The effect of salmeterol on the early and late-phase reaction to bronchial allergen and postchallenge variation in bronchial reactivity, blood eosinophils, serum eosinophil cationic protein and serum eosinophils protein X. Allergy 1993;48: 377-382.
9. Di Lorenzo G, Morici G, Norrito F, Mansueto P, Melluso M, D'ambrosio PF, Sangiorgi GB: Comparison of the effects of salmeterol and salbutamol on clinical activity and eosinophil cationic protein serum levels during the pollen season in atopic asthmatics. Clin Exp Allergy 1995;25:951-956.
10. Anderson GP: Pharmacology of formoterol: An innovative bronchodilator; in Anderson GP, Chapman ID, Morley J (eds): in Agents and Actions Supplements. Basel, Birkhäuser, 1991, vol 34: New Drugs for Asthma Therapy, pp 97-115.
11. Rabe KF, Giembycz MA, Dent G, Perkins RS, Evans P, Barnes PJ: Salmeterol is a competitive antagonist at β-adrenoceptors mediating inhibition at respiratory burst in guinea-pig eosinophils. Eur J Pharmacol 1993;231:305-308.
12. Sanjar S, McCabe PR, Reynolds LH: Salmeterol, a long acting beta-2 agonist, inhibits antigen-induced bronchial eosinophil accumulation. Am Rev Respir Dis 1991;143:A755.
13. Beaven MA, Maeyama K, Wolde-Mussie E, Lo TN, Ali H, Cunha-Melo JR: Mechanism of signal transduction in mast cells and basophils: Studies with RBL-2H3 cells. Agents Actions 1987;20:137-145.
14. Shute J: Signal transduction mechanisms in human eosinophils. Clin Exp Allergy 1993;23: 713-717.
15. Hansel TT, De Vries IJM, Iff T, Ris S, Wandzilak M, Betz S, Blaser K, Walker C: An improved immunomagnetic procedure for the isolation of highly purified human blood eosinophils. J Immunol Methods 1991;145:105-110.
16. Sedgwick JB, Vrtis RF, Gourley MF, Busse WW: Stimulus-dependent differences in superoxide anion generation by normal human eosinophils and neutrophils. J Allergy Clin Immunol 1988;81:876-883.
17. Kroegel C, Yukawa T, Dent G, Venge P, Chung KF, Barnes PJ: Stimulation of degranulation from eosinophils by platelet activating factor. J Immunol 1989;142:3518-3526.
18. Munoz NM, Rabe KF, Vita AJ, McAllister K, Mayer D, Weiss M, Leff AR: Paradoxical blockade of beta adrenergically mediated inhibition of stimulated eosinophil secretion by salmeterol. J Pharmacol Exp Ther 1995;273: 850-854.
19. Bach MK, Brashler JR, Petzold EN, Sanders ME: Superoxide production by human eosinophils can be inhibited in an agonist-dependent manner. Agents Actions 1992;35:1-11.
20. van der Bruggen T, Kok PTM, Raaijmakers JAM, Verhoeven AJ, Kessels RGC, Lammers JWJ, Koenderman L: Cytokine priming of respiratory burst in human eosinophils is calcium independent and accompanied by induction of tyrosine kinase activity. J Leukoc Biol 1993;53: 347-353.
21. Giembycz MA: Could isoenzyme-selective phosphodiesterase inhibitors render bronchodilator therapy redundant in the treatment of bronchial asthma? Biochem Pharmacol 1992;43: 2041-2051.
22. Hatzelmann A, Tenor H, Schudt C: Differential effects of non-selective and selective phosphodiesterase inhibitors on human eosinophil functions. Br J Pharmacol 1995;114:821-831.
23. Church MK, Young KO: The characteristics of inhibition of histamine release from human lung fragments by sodium cromoglycate, salbutamol and chlorpromazine. Br J Pharmacol 1983;78:671-679.
24. Butchers PR, Vardey CJ, Johnson M: Salmeterol, a potent and long-acting inhibitor of inflammatory mediator release from human lung. Br J Pharmacol 1991;104:672-676.
25. Sedgwick JB, Calhoun WJ, Vrtis RF, Bates ME, McAllister PK, Busse WW: Comparison of airway and blood eosinophil function after in vivo antigen challenge. J Immunol 1992;149:3710-3718.
26. Zeck-Kapp G, Kroegel C, Riede UN, Kapp A: Mechanism of human eosinophil activation by complement protein C5a and PAF: Similar functional responses are accompanied by different morphologic alterations. Allergy 1995; 50:43-47.
27. Gleich GJ, Adolphson CR: The eosinophil leukocyte: Structure and function. Adv Immunol 1986;39:177-253.