M-cell targeted polymeric lipid nanoparticles containing a toll-like receptor agonist to boost oral immunity

International Journal of Pharmaceutics

Volumn 473, Issue 1-2, 2014, Pages 296-303

  Ma, Tongtong ^a,b   Wang, Lianyan ^b   Yang, Tingyuan ^b   Ma, Guanghui ^b   Wang, Siling ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b INSTITUTE OF PROCESS ENGINEERING   (China)

Author keywords

M cell targeting; Oral delivery; Polymeric lipid nanoparticles; Toll like receptor agonist; Vaccine

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; LIPID NANOPARTICLE; OVALBUMIN; PHOSPHORYL LIPID A; POLYGLACTIN; ULEX EUROPAEUS AGGLUTININ; ULEX EUROPAEUS AGGLUTININ 1; UNCLASSIFIED DRUG; ANTIGEN; IMMUNOLOGICAL ADJUVANT; LIPID A; NANOPARTICLE; PLANT LECTIN; POLYGLYCOLIC ACID; TOLL LIKE RECEPTOR; ULEX EUROPAEUS LECTINS;

ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ARTICLE; CELL ADHESION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; EX VIVO STUDY; FEMALE; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IN VITRO STUDY; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PARTICLE SIZE; POLYMERIZATION; PRIORITY JOURNAL; TARGET CELL; VACCINATION; AGONISTS; ANALOGS AND DERIVATIVES; ANIMAL; BAGG ALBINO MOUSE; BLOOD; CACO 2 CELL LINE; CELL LINE; CHEMISTRY; DENDRITIC CELL; IMMUNOLOGY; INTESTINE; ORAL DRUG ADMINISTRATION;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, ORAL; ANIMALS; ANTIGENS; CACO-2 CELLS; CELL LINE; DENDRITIC CELLS; FEMALE; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INTESTINES; LIPID A; MICE, INBRED BALB C; NANOPARTICLES; OVALBUMIN; PLANT LECTINS; POLYGLYCOLIC ACID; TOLL-LIKE RECEPTORS; VACCINATION;

EID: 84905003150     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.06.052     Document Type: Article

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