Flavin monooxygenase metabolism: Why medicinal chemists should matter

Journal of Medicinal Chemistry

Volumn 57, Issue 14, 2014, Pages 6183-6196

  Cruciani, Gabriele ^a   Valeri, Aurora ^a   Goracci, Laura ^a   Pellegrino, Roberto Maria ^a   Buonerba, Federica ^a   Baroni, Massimo ^b  

^a UNIVERSITY OF PERUGIA   (Italy)

^b Molecular Discovery Limited   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 3A4; FLAVIN MONOOXYGENASE; QUERCETIN; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE; XENOBIOTIC AGENT;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; COMPUTER MODEL; DETOXIFICATION; ELECTROPHILICITY; ENZYME METABOLISM; HUMAN; IN VITRO STUDY; LIPIDOSIS; LIQUID CHROMATOGRAPHY; LIVER TOXICITY; MASS SPECTROMETRY; NEUROTOXICITY; NUCLEOPHILICITY; OXIDATION; PROTON NUCLEAR MAGNETIC RESONANCE;

BIOCATALYSIS; COMPUTER SIMULATION; HUMANS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MOLECULAR STRUCTURE; OXYGENASES; RECOMBINANT PROTEINS; REPRODUCIBILITY OF RESULTS; SUBSTRATE SPECIFICITY;

EID: 84904988793     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm5007098     Document Type: Article

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