In vitro metabolism of the M1-muscarinic agonist 5-(2-ethyl-2H-tetrazol- 5-yl)-1-methyl-1,2,3,6-tetrahydropyridine by human hepatic cytochromes P-450 determined at PH 7.4 and 8.5

Drug Metabolism and Disposition

Volumn 27, Issue 1, 1999, Pages 125-132

  Jensen, Klaus Gjervig ^a   Dalgaard, Lars ^a  

^a H LUNDBECK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

5 (2 ETHYL 2H TETRAZOL 5 YL) 1 METHYL 1,2,3,6 TETRAHYDROPYRIDINE MALEATE; ALVAMELINE; COUMARIN; CYTOCHROME P450; DEBRISOQUINE 4 HYDROXYLASE; DIETHYLDITHIOCARBAMIC ACID; DRUG METABOLITE; ETHOXYRESORUFIN; FURAFYLLINE; KETOCONAZOLE; MUSCARINIC M1 RECEPTOR AGONIST; PHENACETIN O DEETHYLASE; QUINIDINE; RESORUFIN; SULFAPHENAZOLE; TRANYLCYPROMINE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER MICROSOME; LYMPHOBLASTOID CELL; PH; PRIORITY JOURNAL; SENILE DEMENTIA;

CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; HYDROGEN-ION CONCENTRATION; MICROSOMES, LIVER; MUSCARINIC AGONISTS; PYRIDINES; TETRAZOLES;

EID: 0033047284     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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