Persistent reduction of cocaine seeking by pharmacological manipulation of adenosine A1 and A2A receptors during extinction training in rats

Psychopharmacology

Volumn 231, Issue 16, 2014, Pages 3179-3188

  O'Neill, Casey E ^a   Hobson, Benjamin D ^a   Levis, Sophia C ^a   Bachtell, Ryan K ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

Adenosine; Cocaine; Dopamine; Extinction; Reinstatement; Self administration

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 5 AMINO 2 (2 FURYL) 7 [3 (4 METHOXYPHENYL)PROPYL]PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; 6 N CYCLOPENTYLADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR ANTAGONIST; COCAINE; QUINPIROLE; UNCLASSIFIED DRUG; [2 (2 FURANYL) 7 [3 (4 METHOXYPHENYL)PROPYL] 7H PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDIN 4 AMINE]; 2-(4-(2-CARBOXYETHYL)PHENETHYLAMINO)-5'-N-ETHYLCARBOXAMIDOADENOSINE; ADENOSINE; ADENOSINE A1 RECEPTOR AGONIST; ADENOSINE A2 RECEPTOR AGONIST; ADENOSINE A2 RECEPTOR ANTAGONIST; DOPAMINE RECEPTOR STIMULATING AGENT; N(6)-CYCLOPENTYLADENOSINE; PHENETHYLAMINE DERIVATIVE; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE; SCH 442416;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COCAINE DEPENDENCE; CONDITIONING; DOSE RESPONSE; DRUG ACTIVITY; DRUG SELF ADMINISTRATION; EXTINCTION TRAINING; LOCOMOTION; LOW DRUG DOSE; MALE; NONHUMAN; PATHOGENESIS; PRESYNAPTIC NERVE; PRIORITY JOURNAL; RAT; REINSTATEMENT; TRAINING; TREATMENT RESPONSE; ANALOGS AND DERIVATIVES; ANIMAL; ASSOCIATION; DRUG EFFECTS; DRUG SEEKING BEHAVIOR; PSYCHOLOGY; RECURRENT DISEASE; REINFORCEMENT; SPRAGUE DAWLEY RAT;

ADENOSINE; ADENOSINE A1 RECEPTOR AGONISTS; ADENOSINE A2 RECEPTOR AGONISTS; ADENOSINE A2 RECEPTOR ANTAGONISTS; ANIMALS; COCAINE-RELATED DISORDERS; CUES; DOPAMINE AGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG-SEEKING BEHAVIOR; EXTINCTION, PSYCHOLOGICAL; MALE; PHENETHYLAMINES; PYRAZOLES; PYRIMIDINES; QUINPIROLE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ADENOSINE A1; RECEPTOR, ADENOSINE A2A; RECURRENCE; SELF ADMINISTRATION;

EID: 84904986800     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-014-3489-2     Document Type: Article

References (66)

1. Bachtell RK, Whisler K, Karanian D, Self DW (2005) Effects of intra-nucleus accumbens shell administration of dopamine agonists and antagonists on cocaine-taking and cocaine-seeking behaviors in the rat. Psychopharmacology (Berlin) 183:41-53
2. Bachtell RK, Self DW (2009) Effects of adenosine A(2A) receptor stimulation on cocaine-seeking behavior in rats. Psychopharmacology (Berlin) 206:469-478
3. Barrett AC, Negus SS, Mello NK, Caine SB (2005) Effect of GABA agonists and GABA-A receptor modulators on cocaine- and food-maintained responding and cocaine discrimination in rats. J Pharmacol Exp Ther 315:858-871
4. Bouton ME (2004) Context and behavioral processes in extinction. Learn Mem 11:485-494
5. Carabaza A, Cabre F, Rotllan E, Gomez M, Gutierrez M, Garcia ML et al (1996) Stereoselective inhibition of inducible cyclooxygenase by chiral nonsteroidal antiinflammatory drugs. J Clin Pharmacol 36:505-512
6. Ciruela F, Casado V, Rodrigues RJ, Lujan R, Burgueno J, Canals M et al (2006) Presynaptic control of striatal glutamatergic neurotransmission by adenosine A1-A2A receptor heteromers. J Neurosci 26:2080-2087
7. Corsi C, Pazzagli M, Bianchi L, Della Corte L, Pepeu G, Pedata F (1997) In vivo amino acid release from the striatum of aging rats: adenosine modulation. Neurobiol Aging 18:243-250
8. Cristovao-Ferreira S, Navarro G, Brugarolas M, Perez-Capote K, Vaz SH, Fattorini G et al (2013) A1R-A2AR heteromers coupled to Gs and G i/0 proteins modulate GABA transport into astrocytes. Purinergic Signal 9:433-449
9. 2 receptors is time-dependent and associated with behavioral sensitization. Neuropsychopharmacology 26:18-26
10. Di Ciano P, Everitt BJ (2003) The GABA(B) receptor agonist baclofen attenuates cocaine- and heroin-seeking behavior by rats. Neuropsychopharmacology 28:510-518
11. Dixon AK, Gubitz AK, Sirinathsinghji DJ, Richardson PJ, Freeman TC (1996) Tissue distribution of adenosine receptor mRNAs in the rat. Br J Pharmacol 118:1461-1468
12. Doyle SE, Breslin FJ, Rieger JM, Beauglehole A, Lynch WJ (2012) Time and sex-dependent effects of an adenosine A2A/A1 receptor antagonist on motivation to self-administer cocaine in rats. Pharmacol Biochem Behav 102:257-263
13. Ferre S, Quiroz C, Orru M, Guitart X, Navarro G, Cortes A et al (2011) Adenosine A(2A) receptors and A(2A) receptor heteromers as key players in striatal function. Front Neuroanat 5:36
14. Filip M, Frankowska M, Zaniewska M, Przegalinski E, Muller CE, Agnati L et al (2006) Involvement of adenosine A2A and dopamine receptors in the locomotor and sensitizing effects of cocaine. Brain Res 1077:67-80
15. Filip M, Frankowska M, Zaniewska M, Golda A, Przegalinski E, Vetulani J (2007) Diverse effects of GABA-mimetic drugs on cocaine-evoked self-administration and discriminative stimulus effects in rats. Psychopharmacology 192:17-26
16. 2 dopamine receptors in rat striatum. Brain Res Mol Brain Res 14:186-195
17. 2 dopamine receptors in the acquisition and expression of cocaine-induced conditioned increases in locomotor behavior. Behav Pharmacol 4:375-387
18. Frankowska M, Wydra K, Faron-Gorecka A, Zaniewska M, Kusmider M, Dziedzicka-Wasylewska M et al (2008) Neuroadaptive changes in the rat brain GABA(B) receptors after withdrawal from cocaine self-administration. Eur J Pharmacol 599:58-64
19. 2-like/Gi protein coupling in rat striatum. Addict Biol 18:455-466
20. Fredholm BB, Irenius E, Kull B, Schulte G (2001) Comparison of the potency of adenosine as an agonist at human adenosine receptors expressed in Chinese hamster ovary cells. Biochem Pharmacol 61:443-448
21. 2 dopamine receptor agonists to induce and modulate expression and reinstatement of cocaine place preference in rats. Psychopharmacology (Berlin) 191:719-730
22. Grimm JW, See RE (2000) Dissociation of primary and secondary reward-relevant limbic nuclei in an animal model of relapse. Neuropsychopharmacology 22:473-479
23. Hack SP, Christie MJ (2003) Adaptations in adenosine signaling in drug dependence: therapeutic implications. Crit Rev Neurobiol 15:235-274
24. Hammond S, Seymour CM, Burger A, Wagner JJ (2012) D-serine facilitates the effectiveness of extinction to reduce drug-primed reinstatement of cocaine-induced conditioned place preference. Neuropharmacology 64:464-471
25. 2 receptors in rats. Neuropharmacology 63:1172-1181
26. Hobson, BD, O'Neill, CE, Levis, SC, Monteggia, LM, Neve, RL, Self, DW, et al (2013) Adenosine A and Dopamine D Receptor Regulation of AMPA Receptor Phosphorylation and Cocaine-Seeking Behavior. Neuropsychopharmacology
27. Justinova Z, Ferre S, Segal PN, Antoniou K, Solinas M, Pappas LA et al (2003) Involvement of adenosine A1 and A2A receptors in the adenosinergic modulation of the discriminative-stimulus effects of cocaine and methamphetamine in rats. J Pharmacol Exp Ther 307:977-986
28. Justinova Z, Ferre S, Redhi GH, Mascia P, Stroik J, Quarta D et al (2011) Reinforcing and neurochemical effects of cannabinoid CB1 receptor agonists, but not cocaine, are altered by an adenosine A2A receptor antagonist. Addict Biol 16:405-415
29. 2-like receptor mechanisms in relapse to cocaine-seeking behavior: effects of selective antagonists and agonists. J Pharmacol Exp Ther 294:680-687
30. Kirk IP, Richardson PJ (1994) Adenosine A2a receptor-mediated modulation of striatal [3H]GABA and [3H]acetylcholine release. J Neurochem 62:960-966
31. Knackstedt LA, Melendez RI, Kalivas PW (2010a) Ceftriaxone restores glutamate homeostasis and prevents relapse to cocaine seeking. Biol Psychiatry 67:81-84
32. Knackstedt LA, Moussawi K, Lalumiere R, Schwendt M, Klugmann M, Kalivas PW (2010b) Extinction training after cocaine self-administration induces glutamatergic plasticity to inhibit cocaine seeking. J Neurosci 30:7984-7992
33. Knapp CM, Foye MM, Cottam N, Ciraulo DA, Kornetsky C (2001) Adenosine agonists CGS 21680 and NECA inhibit the initiation of cocaine self-administration. Pharmacol Biochem Behav 68:797-803
34. Koob GF, Volkow ND (2010) Neurocircuitry of addiction. Neuropsychopharmacology 35:217-238
35. LaLumiere RT, Niehoff KE, Kalivas PW (2010) The infralimbic cortex regulates the consolidation of extinction after cocaine self-administration. Learn Mem 17:168-175
36. Manzoni O, Pujalte D, Williams J, Bockaert J (1998) Decreased presynaptic sensitivity to adenosine after cocaine withdrawal. J Neurosci 18:7996-8002
37. Marcellino D, Roberts DC, Navarro G, Filip M, Agnati L, Lluis C et al (2007) Increase in A2A receptors in the nucleus accumbens after extended cocaine self-administration and its disappearance after cocaine withdrawal. Brain Res 1143:208-220
38. 6-cyclopentyladenosine and the A1 antagonist 8- cyclopentyltheophylline and its application in a pharmacokinetic study in rats. Journal of chromatography 620:113-120
39. McFarland K, Lapish CC, Kalivas PW (2003) Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior. J Neurosci 23:3531-3537
40. McLaughlin J, See RE (2003) Selective inactivation of the dorsomedial prefrontal cortex and the basolateral amygdala attenuates conditioned-cued reinstatement of extinguished cocaine-seeking behavior in rats. Psychopharmacology 168:57-65
41. 2 dopamine receptor sensitivity predicts cocaine sensitivity and reward in rats. PLoS ONE 8:e78258
42. Mickley GA, Remus JL, Ramos L, Wilson GN, Biesan OR, Ketchesin KD (2012) Acute, but not chronic, exposure to d-cycloserine facilitates extinction and modulates spontaneous recovery of a conditioned taste aversion. Physiol Behav 105:417-427
43. O'Neill CE, LeTendre ML, Bachtell RK (2012) Adenosine A2A receptors in the nucleus accumbens bi-directionally alter cocaine seeking in rats. Neuropsychopharmacology 37:1245-1256
44. Orru M, Bakesova J, Brugarolas M, Quiroz C, Beaumont V, Goldberg SR et al (2011a) Striatal pre- and postsynaptic profile of adenosine A(2A) receptor antagonists. PLoS ONE 6:e16088
45. Orru M, Quiroz C, Guitart X, Ferre S (2011b) Pharmacological evidence for different populations of postsynaptic adenosine A2A receptors in the rat striatum. Neuropharmacology 61:967-974
46. Peters J, LaLumiere RT, Kalivas PW (2008) Infralimbic prefrontal cortex is responsible for inhibiting cocaine seeking in extinguished rats. J Neurosci 28:6046-6053
47. Poleszak E, Malec D (2002) Adenosine receptor ligands and cocaine in conditioned place preference (CPP) test in rats. Pol J Pharmacol 54:119-126
48. Quarta D, Ferre S, Solinas M, You ZB, Hockemeyer J, Popoli P et al (2004) Opposite modulatory roles for adenosine A1 and A2A receptors on glutamate and dopamine release in the shell of the nucleus accumbens. Effects of chronic caffeine exposure. J Neurochem 88:1151-1158
49. Quiroz C, Lujan R, Uchigashima M, Simoes AP, Lerner TN, Borycz J et al (2009) Key modulatory role of presynaptic adenosine A2A receptors in cortical neurotransmission to the striatal direct pathway. Sci World J 9:1321-1344
50. Reissner, KJ, Brown, RM, Spencer, S, Tran, PK, Thomas, CA, Kalivas, PW (2013) Chronic administration of the methylxanthine propentofylline impairs reinstatement to cocaine by a GLT-1-dependent mechanism. Neuropsychopharmacology
51. Schmidt EF, Sutton MA, Schad CA, Karanian DA, Brodkin ES, Self DW (2001) Extinction training regulates tyrosine hydroxylase during withdrawal from cocaine self-administration. J Neurosci 21:RC137
52. Schmidt HD, Pierce RC (2010) Cocaine-induced neuroadaptations in glutamate transmission: potential therapeutic targets for craving and addiction. Ann N Y Acad Sci 1187:35-75
53. 2-like dopamine receptor agonists. Science 271:1586-1589
54. Shalev U, Grimm JW, Shaham Y (2002) Neurobiology of relapse to heroin and cocaine seeking: a review. Pharmacol Rev 54:1-42
55. Shoaib M, Swanner LS, Beyer CE, Goldberg SR, Schindler CW (1998) The GABAB agonist baclofen modifies cocaine self-administration in rats. Behav Pharmacol 9:195-206
56. Suto N, Ecke LE, You ZB, Wise RA (2010) Extracellular fluctuations of dopamine and glutamate in the nucleus accumbens core and shell associated with lever-pressing during cocaine self-administration, extinction, and yoked cocaine administration. Psychopharmacology 211:267-275
57. Sutton MA, Schmidt EF, Choi KH, Schad CA, Whisler K, Simmons D et al (2003) Extinction-induced upregulation in AMPA receptors reduces cocaine-seeking behaviour. Nature 421:70-75
58. Svenningsson P, Fourreau L, Bloch B, Fredholm BB, Gonon F, Le Moine C (1999a) Opposite tonic modulation of dopamine and adenosine on c-fos gene expression in striatopallidal neurons. Neuroscience 89:827-837
59. Svenningsson P, Le Moine C, Fisone G, Fredholm BB (1999b) Distribution, biochemistry and function of striatal adenosine A2A receptors. Prog Neurobiol 59:355-396
60. Swanson RA, Liu J, Miller JW, Rothstein JD, Farrell K, Stein BA et al (1997) Neuronal regulation of glutamate transporter subtype expression in astrocytes. J Neurosci 17:932-940
61. Uys JD, LaLumiere RT (2008) Glutamate: the new frontier in pharmacotherapy for cocaine addiction. CNS Neurol Disord Drug Targets 7:482-491
62. Volterra A, Meldolesi J (2005) Astrocytes, from brain glue to communication elements: the revolution continues. Nat Rev Neurosci 6:626-640
63. Weerts EM, Froestl W, Kaminski BJ, Griffiths RR (2007) Attenuation of cocaine-seeking by GABA B receptor agonists baclofen and CGP44532 but not the GABA reuptake inhibitor tiagabine in baboons. Drug Alcohol Depend 89:206-213
64. Wu J, Lee MR, Kim T, Johng S, Rohrback S, Kang N et al (2011) Regulation of ethanol-sensitive EAAT2 expression through adenosine A1 receptor in astrocytes. Biochem Biophys Res Commun 406:47-52
65. Wydra K, Golembiowska K, Zaniewska M, Kaminska K, Ferraro L, Fuxe K et al (2013) Accumbal and pallidal dopamine, glutamate and GABA overflow during cocaine self-administration and its extinction in rats. Addict Biol 18:307-324
66. Xi ZX, Ramamoorthy S, Shen H, Lake R, Samuvel DJ, Kalivas PW (2003) GABA transmission in the nucleus accumbens is altered after withdrawal from repeated cocaine. J Neurosci 23:3498-3505