Initial D2 dopamine receptor sensitivity predicts cocaine sensitivity and reward in rats

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Merritt, Kathryn E ^a   Bachtell, Ryan K ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COCAINE; DOPAMINE 2 RECEPTOR; QUINPIROLE; DOPAMINE; DOPAMINE RECEPTOR STIMULATING AGENT;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COCAINE DEPENDENCE; CONCENTRATION RESPONSE; DOPAMINERGIC ACTIVITY; LOCOMOTION; MALE; NONHUMAN; PHENOTYPE; PLACE PREFERENCE; PREDICTION; RAT; RECEPTOR SENSITIVITY; REINFORCEMENT; RELIABILITY; REWARD; SENSITIZATION; ANIMAL; DOSE RESPONSE; DRUG SELF ADMINISTRATION; GENE EXPRESSION; GENETICS; INSTRUMENTAL CONDITIONING; METABOLISM; MOTOR ACTIVITY; PSYCHOLOGICAL ASPECT; SPRAGUE DAWLEY RAT;

ANIMALS; BEHAVIOR, ANIMAL; COCAINE; COCAINE-RELATED DISORDERS; CONDITIONING, OPERANT; DOPAMINE; DOPAMINE AGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; MALE; MOTOR ACTIVITY; QUINPIROLE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D2; REINFORCEMENT (PSYCHOLOGY); REWARD; SELF ADMINISTRATION;

EID: 84892586394     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0078258     Document Type: Article

References (55)

1. Wagner FA, Anthony JC (2002) From first drug use to drug dependence; developmental periods of risk for dependence upon marijuana, cocaine, and alcohol. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 26: 479-488.
2. Piazza PV, Le Moal ML (1996) Pathophysiological basis of vulnerability to drug abuse: role of an interaction between stress, glucocorticoids, and dopaminergic neurons. Annual review of pharmacology and toxicology 36: 359-378.
3. Swanson LW (1982) The projections of the ventral tegmental area and adjacent regions: a combined fluorescent retrograde tracer and immunofluorescence study in the rat. Brain research bulletin 9: 321-353.
4. Ritz MC, Lamb RJ, Goldberg SR, Kuhar MJ (1987) Cocaine receptors on dopamine transporters are related to self-administration of cocaine. Science 237: 1219-1223.
5. Anderson SM, Pierce RC (2005) Cocaine-induced alterations in dopamine receptor signaling: implications for reinforcement and reinstatement. Pharmacol Ther 106: 389-403.
6. Volkow ND, Fowler JS, Wang GJ, Baler R, Telang F (2009) Imaging dopamine's role in drug abuse and addiction. Neuropharmacology 56 Suppl 1: 3-8.
7. Volkow ND, Wang GJ, Fowler JS, Logan J, Gatley SJ, et al. (1999) Prediction of reinforcing responses to psychostimulants in humans by brain dopamine D2 receptor levels. The American journal of psychiatry 156: 1440-1443.
8. Caine SB, Negus SS, Mello NK, Patel S, Bristow L, et al. (2002) Role of dopamine D2-like receptors in cocaine self-administration: studies with D2 receptor mutant mice and novel D2 receptor antagonists. The Journal of neuroscience : the official journal of the Society for Neuroscience 22: 2977-2988.
9. Thanos PK, Michaelides M, Umegaki H, Volkow ND (2008) D2R DNA transfer into the nucleus accumbens attenuates cocaine self-administration in rats. Synapse 62: 481-486.
10. Bailey A, Metaxas A, Yoo JH, McGee T, Kitchen I (2008) Decrease of D2 receptor binding but increase in D2-stimulated G-protein activation, dopamine transporter binding and behavioural sensitization in brains of mice treated with a chronic escalating dose 'binge' cocaine administration paradigm. Eur J Neurosci 28: 759-770.
11. Briand LA, Flagel SB, Seeman P, Robinson TE (2008) Cocaine selfadministration produces a persistent increase in dopamine D2 High receptors. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 18: 551-556.
12. Bachtell RK, Choi KH, Simmons DL, Falcon E, Monteggia LM, et al. (2008) Role of GluR1 expression in nucleus accumbens neurons in cocaine sensitization and cocaine-seeking behavior. Eur J Neurosci 27: 2229-2240.
13. Collins GT, Truong YN, Levant B, Chen J, Wang S, et al. (2011) Behavioral sensitization to cocaine in rats: evidence for temporal differences in dopamine D3 and D2 receptor sensitivity. Psychopharmacology 215: 609-620.
14. Edwards S, Whisler KN, Fuller DC, Orsulak PJ, Self DW (2007) Addictionrelated alterations in D1 and D2 dopamine receptor behavioral responses following chronic cocaine self-administration. Neuropsychopharmacology 32: 354-366.
15. Ujike H, Akiyama K, Otsuki S (1990) D-2 but not D-1 dopamine agonists produce augmented behavioral response in rats after subchronic treatment with methamphetamine or cocaine. Psychopharmacology (Berl) 102: 459-464.
16. Bachtell RK, Whisler K, Karanian D, Self DW (2005) Effects of intra-nucleus accumbens shell administration of dopamine agonists and antagonists on cocaine-taking and cocaine-seeking behaviors in the rat. Psychopharmacology (Berl) 183: 41-53.
17. De Vries TJ, Schoffelmeer AN, Binnekade R, Vanderschuren LJ (1999) Dopaminergic mechanisms mediating the incentive to seek cocaine and heroin following long-term withdrawal of IV drug self-administration. Psychopharmacology (Berl) 143: 254-260.
18. Dias C, Lachize S, Boilet V, Huitelec E, Cador M (2004) Differential effects of dopaminergic agents on locomotor sensitisation and on the reinstatement of cocaine-seeking and food-seeking behaviour. Psychopharmacology 175: 105-115.
19. Khroyan TV, Barrett-Larimore RL, Rowlett JK, Spealman RD (2000) Dopamine D1- and D2-like receptor mechanisms in relapse to cocaine-seeking behavior: Effects of selective antagonists and agonists. J Pharmacol Exp Ther 294: 680-687.
20. Schmidt HD, Pierce RC (2006) Cooperative activation of D1-like and D2-like dopamine receptors in the nucleus accumbens shell is required for the reinstatement of cocaine-seeking behavior in the rat. Neuroscience 142: 451-461.
21. Self DW, Barnhart WJ, Lehman DA, Nestler EJ (1996) Opposite modulation of cocaine-seeking behavior by D1- and D2-like dopamine receptor agonists. Science 271: 1586-1589.
22. O'Neill CE, LeTendre ML, Bachtell RK (2012) Adenosine A2A receptors in the nucleus accumbens bi-directionally alter cocaine seeking in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 37: 1245-1256.
23. White FJ, Wang RY (1986) Electrophysiological evidence for the existence of both D-1 and D-2 dopamine receptors in the rat nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience 6: 274-280.
24. Hu XT, Wang RY (1988) Disinhibition of nucleus accumbens neurons by the dopamine D2 receptor agonist LY-141865: prevented by 6-OHDA pretreatment. Brain research 444: 389-393.
25. Eilam D, Szechtman H (1989) Biphasic effect of D-2 agonist quinpirole on locomotion and movements. European journal of pharmacology 161: 151-157.
26. Piazza PV, Deminiere JM, Le Moal M, Simon H (1989) Factors that predict individual vulnerability to amphetamine self-administration. Science 245: 1511-1513.
27. Piazza PV, Deroche-Gamonent V, Rouge-Pont F, Le Moal M (2000) Vertical shifts in self-administration dose-response functions predict a drug-vulnerable phenotype predisposed to addiction. J Neurosci 20: 4226-4232.
28. Gulley JM, Hoover BR, Larson GA, Zahniser NR (2003) Individual differences in cocaine-induced locomotor activity in rats: behavioral characteristics, cocaine pharmacokinetics, and the dopamine transporter. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 28: 2089-2101.
29. Sabeti J, Gerhardt GA, Zahniser NR (2003) Individual differences in cocaineinduced locomotor sensitization in low and high cocaine locomotor-responding rats are associated with differential inhibition of dopamine clearance in nucleus accumbens. The Journal of pharmacology and experimental therapeutics 305: 180-190.
30. Allen RM, Everett CV, Nelson AM, Gulley JM, Zahniser NR (2007) Low and high locomotor responsiveness to cocaine predicts intravenous cocaine conditioned place preference in male Sprague-Dawley rats. Pharmacology, biochemistry, and behavior 86: 37-44.
31. Mandt BH, Schenk S, Zahniser NR, Allen RM (2008) Individual differences in cocaine-induced locomotor activity in male Sprague-Dawley rats and their acquisition of and motivation to self-administer cocaine. Psychopharmacology 201: 195-202.
32. Sokoloff P, Giros B, Martres MP, Bouthenet ML, Schwartz JC (1990) Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics. Nature 347: 146-151.
33. Kostrzewa RM, Brus R (1991) Is dopamine-agonist induced yawning behavior a D3 mediated event? Life sciences 48: PL129.
34. Kurashima M, Yamada K, Nagashima M, Shirakawa K, Furukawa T (1995) Effects of putative dopamine D3 receptor agonists, 7-OH-DPAT, and quinpirole, on yawning, stereotypy, and body temperature in rats. Pharmacology, biochemistry, and behavior 52: 503-508.
35. Deminiere JM, Piazza PV, Le Moal M, Simon H (1989) Experimental approach to individual vulnerability to psychostimulant addiction. Neuroscience and biobehavioral reviews 13: 141-147.
36. Hooks MS, Jones GH, Smith AD, Neill DB, Justice JB, Jr. (1991) Individual differences in locomotor activity and sensitization. Pharmacology, biochemistry, and behavior 38: 467-470.
37. Hooks MS, Juncos JL, Justice JB, Jr., Meiergerd SM, Povlock SL, et al. (1994) Individual locomotor response to novelty predicts selective alterations in D1 and D2 receptors and mRNAs. The Journal of neuroscience : the official journal of the Society for Neuroscience 14: 6144-6152.
38. Hooks MS, Jones DN, Holtzman SG, Juncos JL, Kalivas PW, et al. (1994) Individual differences in behavior following amphetamine, GBR-12909, or apomorphine but not SKF-38393 or quinpirole. Psychopharmacology 116: 217-225.
39. Flagel SB, Robinson TE, Clark JJ, Clinton SM, Watson SJ, et al. (2010) An animal model of genetic vulnerability to behavioral disinhibition and responsiveness to reward-related cues: implications for addiction. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 35: 388-400.
40. Seeman P, Weinshenker D, Quirion R, Srivastava LK, Bhardwaj SK, et al. (2005) Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis. Proc Natl Acad Sci U S A 102: 3513-3518.
41. Marinelli M, White FJ (2000) Enhanced vulnerability to cocaine selfadministration is associated with elevated impulse activity of midbrain dopamine neurons. J Neurosci 20: 8876-8885.
42. Fattore L, Piras G, Corda MG, Giorgi O (2009) The Roman high- and lowavoidance rat lines differ in the acquisition, maintenance, extinction, and reinstatement of intravenous cocaine self-administration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 34: 1091-1101.
43. Giorgi O, Piras G, Corda MG (2007) The psychogenetically selected Roman high- and low-avoidance rat lines: a model to study the individual vulnerability to drug addiction. Neuroscience and biobehavioral reviews 31: 148-163.
44. Schramm-Sapyta NL, Cauley MC, Stangl DK, Glowacz S, Stepp KA, et al. (2011) Role of individual and developmental differences in voluntary cocaine intake in rats. Psychopharmacology 215: 493-504.
45. Rilke O, May T, Oehler J, Wolffgramm J (1995) Influences of housing conditions and ethanol intake on binding characteristics of D2, 5-HT1A, and benzodiazepine receptors of rats. Pharmacology, biochemistry, and behavior 52: 23-28.
46. Del Arco A, Zhu S, Terasmaa A, Mohammed AH, Fuxe K (2004) Hyperactivity to novelty induced by social isolation is not correlated with changes in D2 receptor function and binding in striatum. Psychopharmacology 171: 148-155.
47. Grant KA, Shively CA, Nader MA, Ehrenkaufer RL, Line SW, et al. (1998) Effect of social status on striatal dopamine D2 receptor binding characteristics in cynomolgus monkeys assessed with positron emission tomography. Synapse 29: 80-83.
48. Morgan D, Grant KA, Gage HD, Mach RH, Kaplan JR, et al. (2002) Social dominance in monkeys: dopamine D2 receptors and cocaine self-administration. Nat Neurosci 5: 169-174.
49. Papp M, Muscat R, Willner P (1993) Subsensitivity to rewarding and locomotor stimulant effects of a dopamine agonist following chronic mild stress. Psychopharmacology 110: 152-158.
50. Papp M, Klimek V, Willner P (1994) Parallel changes in dopamine D2 receptor binding in limbic forebrain associated with chronic mild stress-induced anhedonia and its reversal by imipramine. Psychopharmacology 115: 441-446.
51. Puglisi-Allegra S, Kempf E, Schleef C, Cabib S (1991) Repeated stressful experiences differently affect brain dopamine receptor subtypes. Life sciences 48: 1263-1268.
52. Henry C, Guegant G, Cador M, Arnauld E, Arsaut J, et al. (1995) Prenatal stress in rats facilitates amphetamine-induced sensitization and induces long-lasting changes in dopamine receptors in the nucleus accumbens. Brain research 685: 179-186.
53. Cabib S, Giardino L, Calza L, Zanni M, Mele A, et al. (1998) Stress promotes major changes in dopamine receptor densities within the mesoaccumbens and nigrostriatal systems. Neuroscience 84: 193-200.
54. Dziedzicka-Wasylewska M, Willner P, Papp M (1997) Changes in dopamine receptor mRNA expression following chronic mild stress and chronic antidepressant treatment. Behavioural pharmacology 8: 607-618.
55. Carr KD, Kim GY, Cabeza de Vaca S (2001) Rewarding and locomotoractivating effects of direct dopamine receptor agonists are augmented by chronic food restriction in rats. Psychopharmacology 154: 420-428.