Role of defective ERK phosphorylation in the impaired GM-CSF-induced oxidative response of neutrophils in elderly humans

Mechanisms of Ageing and Development

Volumn 125, Issue 8, 2004, Pages 539-546

  Tortorella, Cosimo ^a   Stella, Isabella ^a   Piazzolla, Giuseppina ^a   Simone, Olivia ^a   Cappiello, Valentina ^a   Antonaci, Salvatore ^a  

^a UNIVERSITY OF BARI   (Italy)

Author keywords

Ageing; ERK1 2; GM CSF; Neutrophils; p38MAPK; Respiratory burst; TNF

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ENZYME INHIBITOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; OXIDE; TUMOR NECROSIS FACTOR ALPHA;

AGED; AGING; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; MALE; NEUTROPHIL; NORMAL HUMAN; OXIDATION; PHOSPHORYLATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

AGED; AGING; BLOTTING, WESTERN; CELL SEPARATION; ENZYME INHIBITORS; FEMALE; FLAVONOIDS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; IMIDAZOLES; INDICATORS AND REAGENTS; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; NEUTROPHILS; OXIDATION-REDUCTION; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PYRIDINES; RESPIRATORY BURST; SUPEROXIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 4344626452     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2004.06.001     Document Type: Article

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