mTOR mediates human trophoblast invasion through regulation of matrix-remodeling enzymes and is associated with serine phosphorylation of STAT3

Experimental Cell Research

Volumn 315, Issue 10, 2009, Pages 1724-1733

  Busch, Susann ^a   Renaud, Stephen J ^b   Schleussner, Ekkehard ^a   Graham, Charles H ^b   Markert, Udo R ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b QUEEN S UNIVERSITY   (Canada)

Author keywords

Cell invasion; Mammalian target of rapamycin; Matrix metalloproteinase; Signal transducer and activator of transcription; Trophoblast; Urokinase like plasminogen activator

Indexed keywords

GELATINASE A; GELATINASE B; JANUS KINASE; MAMMALIAN TARGET OF RAPAMYCIN; PLASMINOGEN ACTIVATOR INHIBITOR; RAPAMYCIN; S6 KINASE; SERINE; SMALL INTERFERING RNA; STAT3 PROTEIN; UROKINASE;

ANIMAL CELL; ARTICLE; CELL GROWTH; CELL IMMORTALIZATION; CELL INVASION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME MECHANISM; ENZYME REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TROPHOBLAST;

MAMMALIA; MURINAE;

BLOTTING, WESTERN; CELL EXTRACTS; CELL MOVEMENT; CELL PROLIFERATION; COLORIMETRY; CULTURE MEDIA, CONDITIONED; EXTRACELLULAR MATRIX; FEMALE; HUMANS; MODELS, BIOLOGICAL; PHOSPHORYLATION; PHOSPHOSERINE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PREGNANCY; PROTEIN KINASES; STAT3 TRANSCRIPTION FACTOR; TOR SERINE-THREONINE KINASES; TROPHOBLASTS;

EID: 67349214601     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2009.01.026     Document Type: Article

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