How a replication origin and matrix attachment region accelerate gene amplification under replication stress in mammalian cells

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Tanaka, Shun Suke ^a   Mitsuda, Sho Hei ^a   Shimizu, Noriaki ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROFOLATE REDUCTASE; METHOTREXATE;

ARTICLE; CELL ELONGATION; CHROMOSOMAL LOCALIZATION; CHROMOSOME ANALYSIS; CONTROLLED STUDY; DHFR GENE; DNA DAMAGE CHECKPOINT; DNA REPLICATION ORIGIN; GENE AMPLIFICATION; GENE EXPRESSION; GENOTOXICITY; MAMMAL CELL; MATRIX ATTACHMENT REGION; MICRONUCLEUS; PLASMID; ANIMAL; CHO CELL LINE; CRICETULUS; DNA REPLICATION; GENETICS; HAMSTER; PHYSIOLOGICAL STRESS;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; DNA REPLICATION; GENE AMPLIFICATION; MATRIX ATTACHMENT REGIONS; REPLICATION ORIGIN; STRESS, PHYSIOLOGICAL; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 84904878048     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0103439     Document Type: Article

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