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Volumn 84, Issue , 2014, Pages 491-504
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Design, synthesis, antimicrobial evaluation and molecular docking studies of some new thiophene, pyrazole and pyridone derivatives bearing sulfisoxazole moiety
a
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Author keywords
Antimicrobial agents; Molecular docking; Pyridone; Sulfonamide; Thiophene
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Indexed keywords
2 CYANO N [4 [[(3,4 DIMETHYLISOXAZOL 5 YL)AMINO]SULFONYL] PHENYL) 2 (PHENYL HYDRAZANO)ACETAMIDE;
2 CYANO N [4 [[(3,4 DIMETHYLISOXAZOL 5 YL)AMINO]SULFONYL] PHENYL] 2 [(4 METHOXYPHENYL)HYDRAZONO]ACETAMIDE;
2 CYANO N [4 [[(3,4 DIMETHYLISOXAZOL 5 YL)AMINO]SULFONYL] PHENYL] 2 [(4 METHYL PHENYL)HYDRAZONO]ACETAMIDE;
2 CYANO N [4 [[(3,4 DIMETHYLISOXAZOL 5 YL)AMINO]SULFONYL] PHENYL] 3 (2 FURYL) ACRYLAMIDE;
2 CYANO N [4 [[(3,4 DIMETHYLISOXAZOL 5 YL)AMINO]SULFONYL] PHENYL] 3 (3 PYRIDYL)ACRYLAMIDE;
2 CYANO N [4 [[(3,4 DIMETHYLISOXAZOL 5 YL)AMINO]SULFONYL] PHENYL] 3 PHENYL ACRYLAMIDE;
2 CYANO N [4 [[(3,4 DIMETHYLISOXAZOL 5 YL)AMINO]SULFONYL]PHENYL] 2 [(4 ETHOXY PHENYL)HYDRAZANO]ACETAMIDE;
4 (3 CYANO 4,6 DIMETHYL 2 OXOPYRIDIN 1(2H) YL) N (3,4 DIMETHYL ISOXAZOL 5 YL)BENZENESULFONAMIDE;
4 AMINO 5 CYANO N [4 [[(3,4 DIMETHYLISOXAZOL 5 YL)AMINO]SULFONYL]PHENYL] 2 (PHENYLAMINO)THIOPHENE 3 CARBOXAMIDE;
4 [3,5 DICYANO 6 (2',3',4',6' TETRA O ACETYL BETA DEXTRO GLUCOPYRANOSYLTHIO) 4 (4 CHLOROPHENYL) 2 OXOPYRIDIN 1(2H) YL] N (3,4 DIMETHYLISOXAZOL 5 YL)BENZENSULFONAMIDE;
4 [3,5 DICYANO 6 MERCAPTO 4 (4 CHLOROPHENYL) 2 OXOPYRIDIN 1(2H) YL] N (3,4 DIMETHYLISOXAZOL 5 YL)BENZENESULFONAMIDE;
4 [6 AMINO 3,5 DICYANO 4 (4 METHOXYPHENYL) 2 OXOPYRIDIN 1(2H) YL] N (3,4 DIMETHYLISOXAZOL 5 YL)BENZELSULFONAMIDE;
5 ACETYL 2 (ADAMANTYLAMINO) 4 AMINO N [4 [[(3,4 DIMETHYLISOXAZOL 5 YL)AMINO] SULFONYL]PHENYL] THIOPHENE 3 CARBOXAMIDE;
5 ACETYL 2 (ALLYLAMINO) 4 AMINO N [4 [[(3,4 DIMETHYLISOXAZOL 5 YL)AMINO]SULFONYL]PHENYL]THIOPHENE 3 CARBOXAMIDE;
5 ACETYL 4 AMINO N [4 [[(3,4 DIMETHYLISOXAZOL 5 YL)AMINO]SULFONYL]PHENYL] 2 (ETHTYLAMINO)THIOPHENE 3 CARBOXAMIDE;
5 ACETYL 4 AMINO N [4 [[(3,4 DIMETHYLISOXAZOL 5 YL)AMINO]SULFONYL]PHENYL] 2 (METHTYLAMINO)THIOPHENE 3 CARBOXAMIDE;
5 ACETYL 4 AMINO N [4 [[(3,4 DIMETHYLISOXAZOL 5 YL)AMINO]SULFONYL]PHENYL] 2 (PHENYLAMINO)THIOPHENE 3 CARBOXAMIDE;
5 AMINO N [4 [[(3,4 DIMETHYLISOXAZOL 5 YL) AMINO]SULFONYL]PHENYL] 3 (4 METHOXYPHENYL) 1H PYRAZOLE 4 CARBOXAMIDE;
ACRYLAMIDE DERIVATIVE;
AMPHOTERICIN B;
AMPICILLIN;
ANTIBIOTIC AGENT;
ANTIFUNGAL AGENT;
GENTAMICIN;
HYDRAZONE DERIVATIVE;
PYRAZOLE DERIVATIVE;
PYRIDONE DERIVATIVE;
SULFAFURAZOLE;
THIOPHENE DERIVATIVE;
UNCLASSIFIED DRUG;
UNINDEXED DRUG;
ANTIINFECTIVE AGENT;
4 AMINOBENZOIC ACID;
5 ACETYL 2 (ADAMANTYLAMINO) 4 AMINO N (4 {[(3,4 DIMETHYLISOXAZOL 5 YL)AMINO] SULFONYL} PHENYL) THIOPHENE 3 CARBOXAMIDE;
6 THIOGLUCOSYLPYRIDONE;
DIHYDROPTEROATE SYNTHASE;
HETEROCYCLIC COMPOUND;
PTERIN;
SULFONAMIDE;
ABSORPTION;
AGAR DIFFUSION;
ALKYLATION;
ANTIBACTERIAL ACTIVITY;
ANTIFUNGAL ACTIVITY;
ANTIMICROBIAL ACTIVITY;
ARTICLE;
ASPERGILLUS FUMIGATUS;
BACILLUS SUBTILIS;
CARBON NUCLEAR MAGNETIC RESONANCE;
CONFORMATIONAL TRANSITION;
CONTROLLED STUDY;
CRYSTAL STRUCTURE;
CYCLIZATION;
DRUG DESIGN;
DRUG SYNTHESIS;
ESCHERICHIA COLI;
GROWTH INHIBITION;
HYDROGEN BOND;
IN VITRO STUDY;
KLEBSIELLA PNEUMONIAE;
KNOEVENAGEL CONDENSATION;
MICHAEL ADDITION;
MINIMUM INHIBITORY CONCENTRATION;
MOLECULAR DOCKING;
MOLECULAR MODEL;
NONHUMAN;
PROTON NUCLEAR MAGNETIC RESONANCE;
STAPHYLOCOCCUS EPIDERMIDIS;
STREPTOCOCCUS PNEUMONIAE;
STRUCTURE ACTIVITY RELATION;
SYNCEPHALASTRUM RACEMOSUM;
ASPERGILLUS;
CHEMICAL STRUCTURE;
CHEMISTRY;
DOSE RESPONSE;
DRUG EFFECTS;
MICROBIAL SENSITIVITY TEST;
SYNTHESIS;
DRUG SCREENING;
INFRARED SPECTROMETRY;
ANTI-BACTERIAL AGENTS;
ANTIFUNGAL AGENTS;
ASPERGILLUS;
BACILLUS SUBTILIS;
DOSE-RESPONSE RELATIONSHIP, DRUG;
DRUG DESIGN;
ESCHERICHIA COLI;
MICROBIAL SENSITIVITY TESTS;
MOLECULAR DOCKING SIMULATION;
MOLECULAR STRUCTURE;
PYRAZOLES;
PYRIDONES;
STRUCTURE-ACTIVITY RELATIONSHIP;
SULFISOXAZOLE;
THIOPHENES;
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EID: 84904870114
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2014.07.052 Document Type: Article |
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Times cited : (125)
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References (39)
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