IN VITRO ANTI-OXIDATIVE ACTIVITIES OF THE VARIOUS PARTS OF PARKIA BIGLOBOSA AND GC-MS ANALYSIS OF EXTRACTS WITH HIGH ACTIVITY

African Journal of Traditional, Complementary and Alternative Medicines

Volumn 10, Issue 5, 2013, Pages 283-291

  Ibrahim, M A ^a   Koorbanally, N A ^b   Islam, M S ^a  

^a School of Life Sciences   (South Africa)

^b UNIVERSITY OF KWAZULU NATAL   (South Africa)

Author keywords

Anti oxidative; free radicals; GC MS; Parkia biglobosa; pyrogallol

Indexed keywords

ANTIOXIDANT; DRUG DERIVATIVE; FREE RADICAL; HYDROXYL RADICAL; NITRIC OXIDE; PLANT EXTRACT; PYROGALLOL; REACTIVE OXYGEN METABOLITE;

ANTI-OXIDATIVE; ARTICLE; CHEMISTRY; DRUG ANTAGONISM; FABACEAE; GC-MS; MASS FRAGMENTOGRAPHY; METABOLISM; PARKIA BIGLOBOSA; PLANT STRUCTURES;

ANTI-OXIDATIVE; FREE RADICALS; GC-MS; PARKIA BIGLOBOSA; PYROGALLOL;

ANTIOXIDANTS; FABACEAE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HYDROXYL RADICAL; NITRIC OXIDE; PLANT EXTRACTS; PLANT STRUCTURES; PYROGALLOL; REACTIVE OXYGEN SPECIES;

EID: 84904848414     PISSN: None     EISSN: 25050044     Source Type: Journal    
DOI: 10.4314/ajtcam.v10i5.10     Document Type: Article

References (31)

1. Adetutu, A., Morgan, W.A. and Corcoran, O. (2011). Ethnopharmacological survey and in vitro evaluation of wound-healing plants used in South-western Nigeria. J Ethnopharmacol. 137: 50-56.
2. Agunu, A., Yusuf, S., Andrew, G.O., Zezi, A.U. and Abdurahman, E.M. (2005). Evaluation of five medicinal plants used in diarrhoea treatment in Nigeria. J Ethnopharmacol. 101: 27-30.
3. Arya, V., Yadav, S., Kumar, S. and Yadav, J.P. (2011). Antioxidant activity of organic and aqueous extracts of Cassia occidentalis L in relation to their phenolic content. Nat Prod Res. 25: 1473-1479.
4. Asuzu, I.U. and Harvey, A.L. (2003). The antisnake venom activities of Parkia biglobosa (Mimosaceae) stem bark extract. Toxicon. 42: 763-768.
5. Baskar, P., Rajeswari, V. and Kumar, T.S. (2007). In vitro antioxidant studies in leaves of Annona species. Ind J Exp Biol. 45: 480-485.
6. Calabrese, E.J. and Baldwin, L.A. (2001). U-shaped dose-responses in biology toxicology, and public health. Ann Rev Pub Health. 22: 15-33.
7. Ceriello, A. (2006). Oxidative stress and diabetes-associated complications. Endocr Prac 12: 60-62.
8. Ceriello, A. and Motz, E. (2004). Is oxidative stress the pathogenic mechanism underlying insulin resistance, diabetes, and cardiovascular disease? The common soil hypothesis revisited. Arterioscler Thromb Vasc Biol. 24: 816-823. cereillo
9. Etuk, E.U., Bello, S.O., Isezuo, S.A. and Mohammed, B.J. (2010). Ethnobotanical survey of medicinal plants used for the treatment of diabetes mellitus in the north western region of Nigeria. Asian J Exp Biol Sci. 1: 55-59.
10. Gulcin, I., Beydemir, H.A., Alici, H.A., Elmastas, M. and Buyukokuroglu, M.E. (2004). In vitro antioxidant properties of morphine. Pharmacol Res. 49: 59-66.
11. Hinnerburg, I., Damien, H.J. and Hiltumen, R. (2006). Antioxidant activities of extracts from selected culinary herbs and spices. Food Chem. 97: 122-129.
12. Kalaivani, T. and Mathew, L. (2010). Free radical scavenging activity from leaves of Acacia nilotica (L) Wild ex Delile, an Indian medicinal tree. Food Chem Toxicol. 48: 298-305.
13. Kendig, E.L., Le, H.H., Belcher, S.M. (2010). Defining hormesis: Evaluation of a complex concentration response phenomenon. Int J Toxicol. 29: 235-246.
14. Koehn, F.E. and Carter, G.T. (2005). The evolving role of natural products in drug discovery. Nat Rev Drug Disc. 4: 206–220.
15. Kouadio, F., Kanko, C., Juge, M., Grimaud, N., Jean, A., N’Guessan, Y.T, Petit, J.Y. (2000). Analgesic and anti-inflammatory activities of an extract from Parkia biglobosa used in traditional medicine in the Ivory Coast. Phytother Res. 14: 635-637.
16. Kurian, A.G., Suryanarayanan, S., Raman, A. and Pidakalla, J. (2010). Antioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hearts. Chin Med. 5: 1-7.
17. Lata, H. and Ahuja, G.K. (2003) Role of free radicals in health and disease. Ind J Physiol Allied Sci. 57: 124.
18. McDonald, S., Prenzier, P.D., Autokiwich, M. and Robards, K. (2001). Phenolics content and antioxidant activity of olive oil extracts. Food Chem. 73: 73-84.
19. Millogo-Kone, H., Guissou, I.P., Nacoulma, O. and Traore, A.S. (2008). Comparative study of leaf and stem bark extracts of Parkia biglobosa against enterobacteria. Afr J Trad CAM. 5: 238-243.
20. Odetola, A.A., Akinloye, O., Egunjobi, C., Adekunle, W.A. and Ayoola, A.O. (2006). Possible antidiabetic and antihyperlipidemic effect of fermented Parkia biglobosa (Jacq) extract in alloxan-induced diabetic rats. Clin Exp Pharmacol Physiol. 33: 808-812.
21. Oyaizu, M. (1986). Studies on potent of browning reactions: Antioxidative activities of products of browning reaction prepared from glucosamine. Japan J Nutr. 44: 307-315.
22. Razab, R. and Abdul-Aziz, A. (2010). Antioxidants from tropical herbs. Nat Prod Comm. 5: 441-445.
23. Takayanagi, R., Inoguchi, T. and Ohnaka, K. (2000). Clinical and experimental evidence for oxidative stress as an exacerbating factor of diabetes mellitus. J Clin Biochem Nutr. 48: 72-77.
24. Tokoudagba, J., Auger, C., Breant, L., N’Gom, S., Chabert, P., Idris-Khodja, N., Gbauidi, F., Gbenou, J., Moudachirou, M., Lobstein, A. and Kerth-Schini, V.B. (2010). Procyanidin-rich extracts from Parkia biglobosa (Mimosaceae) leaves cause redox-sensitive endothelium-dependent relaxation involving NO and EDHF in procine coronary artery. J Ethnopharmacol. 132: 246-50.
25. Tuba, A.K. and Gulcin, I. (2008). Antioxidant and radical scavenging properties of curcumin. Chemico-Biol Inter. 174: 27-37.
26. Udobi, C.E. and Onaolapo, J.A. (2009). Phytochemical analysis and antibacterial evaluation of leaf stem bark and root of the African locust bean (Parkia biglobosa). J Med Plants Res. 3: 338-344.
27. van Wyk, B.E. (2008). A broad review of commercially important southern African plants. J Ethnopharmacol. 119: 342-355.
28. Wiernsperger, N.F. (2003). Oxidative stress as a therapeutic target in diabetes: revisiting the controversy. Diabetes Metab. 29: 579-585.
29. Wu, N., Zu, Y., Fu, Y., Kong, Y., Zhao, J., Li, X., Li, J., Wink, M. and Efferth, T. (2010). Antioxidant activities and xanthine oxidase inhibitory effects of extracts and main polyphenolic compounds obtained from Geranium sibiricum L. J Agric Food Chem. 58: 4737-4743.
30. Young, I.S. and Woodside, J.V. (2001). Antioxidants in health and disease. J Clin Pathol. 54: 176-186.
31. Zheng, W. and Wang, S.Y. (2001) Antioxidant activity and phenolic compounds in selected herbs. J Agric Food Chem. 49: 5165-5170.