-
1
-
-
66249129037
-
A dynamic network approach for the study of human phenotypes
-
Hidalgo,C.A., Blumm,N., Barabási,A.-L. and Christakis,N.A. (2009) A dynamic network approach for the study of human phenotypes. PLoS Comput. Biol., 5, e1000353.
-
(2009)
PLoS Comput. Biol.
, vol.5
-
-
Hidalgo, C.A.1
Blumm, N.2
Barabási, A.-L.3
Christakis, N.A.4
-
2
-
-
34547488336
-
Probing genetic overlap among complex human phenotypes
-
Rzhetsky,A., Wajngurt,D., Park,N. and Zheng,T. (2007) Probing genetic overlap among complex human phenotypes. Proc. Natl Acad. Sci. U.S.A., 104, 11694-11699.
-
(2007)
Proc. Natl Acad. Sci. U.S.A.
, vol.104
, pp. 11694-11699
-
-
Rzhetsky, A.1
Wajngurt, D.2
Park, N.3
Zheng, T.4
-
3
-
-
33646058032
-
A text-mining analysis of the human phenome
-
Van Driel,M.A., Bruggeman,J., Vriend,G., Brunner,H.G. and Leunissen,J.A.M. (2006) A text-mining analysis of the human phenome. Eur. J. Hum. Genet., 14, 535-542.
-
(2006)
Eur. J. Hum. Genet.
, vol.14
, pp. 535-542
-
-
Van Driel, M.A.1
Bruggeman, J.2
Vriend, G.3
Brunner, H.G.4
Leunissen, J.A.M.5
-
4
-
-
34547140875
-
The human disease network
-
Goh,K.-I., Cusick,M.E., Valle,D., Childs,B., Vidal,M. and Barabási,A.-L. (2007) The human disease network. Proc. Natl Acad. Sci. U.S.A., 104, 8685-8690.
-
(2007)
Proc. Natl Acad. Sci. U.S.A.
, vol.104
, pp. 8685-8690
-
-
Goh, K.-I.1
Cusick, M.E.2
Valle, D.3
Childs, B.4
Vidal, M.5
Barabási, A.-L.6
-
5
-
-
48249158278
-
The implications of human metabolic network topology for disease comorbidity
-
Lee,D.-S., Park,J., Kay,K.A., Christakis,N.A., Oltvai,Z.N. and Barabási,A.-L. (2008) The implications of human metabolic network topology for disease comorbidity. Proc. Natl Acad. Sci. U.S.A., 105, 9880-9885.
-
(2008)
Proc. Natl Acad. Sci. U.S.A.
, vol.105
, pp. 9880-9885
-
-
Lee, D.-S.1
Park, J.2
Kay, K.A.3
Christakis, N.A.4
Oltvai, Z.N.5
Barabási, A.-L.6
-
6
-
-
76249105279
-
Genome-wide prioritization of disease genes and identification of disease-disease associations from an integrated human functional linkage network
-
Linghu,B., Snitkin,E.S., Hu,Z., Xia,Y. and Delisi,C. (2009) Genome-wide prioritization of disease genes and identification of disease-disease associations from an integrated human functional linkage network. Genome Biol., 10, R91.
-
(2009)
Genome Biol.
, vol.10
-
-
Linghu, B.1
Snitkin, E.S.2
Hu, Z.3
Xia, Y.4
Delisi, C.5
-
7
-
-
33845545435
-
The modular nature of genetic diseases
-
Oti,M. and Brunner,H.G. (2007) The modular nature of genetic diseases. Clin. Genet., 71, 1-11.
-
(2007)
Clin. Genet.
, vol.71
, pp. 1-11
-
-
Oti, M.1
Brunner, H.G.2
-
8
-
-
39649088431
-
Phenome connections
-
Oti,M., Huynen,M.A. and Brunner,H.G. (2008) Phenome connections. Trends Genet., 24, 103-106.
-
(2008)
Trends Genet.
, vol.24
, pp. 103-106
-
-
Oti, M.1
Huynen, M.A.2
Brunner, H.G.3
-
9
-
-
34447521460
-
Human disease classification in the postgenomic era: A complex systems approach to human pathobiology
-
Loscalzo,J., Kohane,I. and Barabasi,A.-L. (2007) Human disease classification in the postgenomic era: a complex systems approach to human pathobiology. Mol. Syst. Biol., 3, 124.
-
(2007)
Mol. Syst. Biol.
, vol.3
, pp. 124
-
-
Loscalzo, J.1
Kohane, I.2
Barabasi, A.-L.3
-
10
-
-
56049107312
-
Obesity and the lung: 4 Obesity and asthma
-
Sin,D.D. and Sutherland,E.R. (2008) Obesity and the lung: 4 Obesity and asthma. Thorax, 63, 1018-1023.
-
(2008)
Thorax
, vol.63
, pp. 1018-1023
-
-
Sin, D.D.1
Sutherland, E.R.2
-
11
-
-
77953734590
-
Pharmacological foundations of cardio-oncology
-
Minotti,G., Salvatorelli,E. and Menna,P. (2010) Pharmacological foundations of cardio-oncology. J. Pharmacol. Exp. Ther., 334, 2-8.
-
(2010)
J. Pharmacol. Exp. Ther.
, vol.334
, pp. 2-8
-
-
Minotti, G.1
Salvatorelli, E.2
Menna, P.3
-
12
-
-
77951240586
-
Network properties of complex human disease genes identified through genome-wide association studies
-
Barrenas,F., Chavali,S., Holme,P., Mobini,R. and Benson,M. (2009) Network properties of complex human disease genes identified through genome-wide association studies. PLoS One, 4, e8090.
-
(2009)
PLoS One
, vol.4
-
-
Barrenas, F.1
Chavali, S.2
Holme, P.3
Mobini, R.4
Benson, M.5
-
13
-
-
84879377451
-
MalaCards: An integrated compendium for diseases and their annotation
-
Rappaport,N., Nativ,N., Stelzer,G., Twik,M., Guan-Golan,Y., Stein,T.I., Bahir,I., Belinky,F., Morrey,C.P., Safran,M. et al. (2013) MalaCards: an integrated compendium for diseases and their annotation. Database (Oxford)., 2013, bat018.
-
(2013)
Database (Oxford).
, vol.2013
-
-
Rappaport, N.1
Nativ, N.2
Stelzer, G.3
Twik, M.4
Guan-Golan, Y.5
Stein, T.I.6
Bahir, I.7
Belinky, F.8
Morrey, C.P.9
Safran, M.10
-
14
-
-
84889679014
-
Discovering disease-disease associations by fusing systems-level molecular data
-
Zitnik,M., Janjíc,V., Larminie,C., Zupan,B. and Przulj,N. (2013) Discovering disease-disease associations by fusing systems-level molecular data. Sci. Rep., 3, 3202.
-
(2013)
Sci. Rep.
, vol.3
, pp. 3202
-
-
Zitnik, M.1
Janjíc, V.2
Larminie, C.3
Zupan, B.4
Przulj, N.5
-
15
-
-
79960914062
-
Exploring and exploiting disease interactions from multi-relational gene and phenotype networks
-
Davis,D.A. and Chawla,N. V (2011) Exploring and exploiting disease interactions from multi-relational gene and phenotype networks. PLoS One, 6, e22670.
-
(2011)
PLoS One
, vol.6
-
-
Davis, D.A.1
Chawla, N.V.2
-
16
-
-
84876545165
-
The Disease and Gene Annotations (DGA): An annotation resource for human disease
-
Peng,K., Xu,W., Zheng,J., Huang,K., Wang,H., Tong,J., Lin,Z., Liu,J., Cheng,W., Fu,D. et al. (2013) The Disease and Gene Annotations (DGA): an annotation resource for human disease. Nucleic Acids Res., 41, D553-560.
-
(2013)
Nucleic Acids Res.
, vol.41
-
-
Peng, K.1
Xu, W.2
Zheng, J.3
Huang, K.4
Wang, H.5
Tong, J.6
Lin, Z.7
Liu, J.8
Cheng, W.9
Fu, D.10
-
17
-
-
33749335282
-
The Connectivity Map: Using gene-expression signatures to connect small molecules, genes, and disease
-
Lamb,J., Crawford,E.D., Peck,D., Modell,J.W., Blat,I.C., Wrobel,M.J., Lerner,J., Brunet,J.-P., Subramanian,A., Ross,K.N. et al. (2006) The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science, 313, 1929-1935.
-
(2006)
Science
, vol.313
, pp. 1929-1935
-
-
Lamb, J.1
Crawford, E.D.2
Peck, D.3
Modell, J.W.4
Blat, I.C.5
Wrobel, M.J.6
Lerner, J.7
Brunet, J.-P.8
Subramanian, A.9
Ross, K.N.10
-
18
-
-
70350227039
-
Systematic evaluation of drug-disease relationships to identify leads for novel drug uses
-
Chiang,A.P. and Butte,A.J. (2009) Systematic evaluation of drug-disease relationships to identify leads for novel drug uses. Clin. Pharmacol. Ther., 86, 507-510.
-
(2009)
Clin. Pharmacol. Ther.
, vol.86
, pp. 507-510
-
-
Chiang, A.P.1
Butte, A.J.2
-
19
-
-
84859638338
-
Use of genome-wide association studies for drug repositioning
-
Sanseau,P., Agarwal,P., Barnes,M.R., Pastinen,T., Richards,J.B., Cardon,L.R. and Mooser,V. (2012) Use of genome-wide association studies for drug repositioning. Nat. Biotechnol., 30, 317-320.
-
(2012)
Nat. Biotechnol.
, vol.30
, pp. 317-320
-
-
Sanseau, P.1
Agarwal, P.2
Barnes, M.R.3
Pastinen, T.4
Richards, J.B.5
Cardon, L.R.6
Mooser, V.7
-
20
-
-
79958754253
-
PREDICT: A method for inferring novel drug indications with application to personalized medicine
-
Gottlieb,A., Stein,G.Y., Ruppin,E. and Sharan,R. (2011) PREDICT: a method for inferring novel drug indications with application to personalized medicine. Mol. Syst. Biol., 7, 496.
-
(2011)
Mol. Syst. Biol.
, vol.7
, pp. 496
-
-
Gottlieb, A.1
Stein, G.Y.2
Ruppin, E.3
Sharan, R.4
-
21
-
-
78049427383
-
Literature mining for the discovery of hidden connections between drugs, genes and diseases
-
Frijters,R., van Vugt,M., Smeets,R., van Schaik,R., de Vlieg,J. and Alkema,W. (2010) Literature mining for the discovery of hidden connections between drugs, genes and diseases. PLoS Comput. Biol., 6.
-
(2010)
PLoS Comput. Biol.
, pp. 6
-
-
Frijters, R.1
Van Vugt, M.2
Smeets, R.3
Van Schaik, R.4
De Vlieg, J.5
Alkema, W.6
-
22
-
-
84877358657
-
Compensating for literature annotation bias when predicting novel drug-disease relationships through Medical Subject Heading Over-representation Profile (MeSHOP) similarity
-
Cheung,W.A., Ouellette,B.F.F. and Wasserman,W.W. (2013) Compensating for literature annotation bias when predicting novel drug-disease relationships through Medical Subject Heading Over-representation Profile (MeSHOP) similarity. BMC Med. Genomics, 6 Suppl 2, S3.
-
(2013)
BMC Med. Genomics
, vol.6
, Issue.SUPPL. 2
-
-
Cheung, W.A.1
Ouellette, B.F.F.2
Wasserman, W.W.3
-
23
-
-
77956548953
-
CytoscapeWeb: An interactive web-based network browser
-
Lopes,C.T., Franz,M., Kazi,F., Donaldson,S.L.,Morris,Q. and Bader,G.D. (2010) CytoscapeWeb: an interactive web-based network browser. Bioinformatics, 26, 2347-2348.
-
(2010)
Bioinformatics
, vol.26
, pp. 2347-2348
-
-
Lopes, C.T.1
Franz, M.2
Kazi, F.3
Donaldson, S.L.4
Morris, Q.5
Bader, G.D.6
-
24
-
-
0345863927
-
The Unified Medical Language System (UMLS): Integrating biomedical terminology
-
Bodenreider,O. (2004) The Unified Medical Language System (UMLS): integrating biomedical terminology. Nucleic Acids Res., 32, D267-D270.
-
(2004)
Nucleic Acids Res.
, vol.32
-
-
Bodenreider, O.1
-
25
-
-
84874271270
-
NCBI GEO: Archive for functional genomics data sets-update
-
Barrett,T., Wilhite,S.E., Ledoux,P., Evangelista,C., Kim,I.F., Tomashevsky,M., Marshall,K.A., Phillippy,K.H., Sherman,P.M., Holko,M. et al. (2013) NCBI GEO: archive for functional genomics data sets-update. Nucleic Acids Res., 41, D991-D995.
-
(2013)
Nucleic Acids Res.
, vol.41
-
-
Barrett, T.1
Wilhite, S.E.2
Ledoux, P.3
Evangelista, C.4
Kim, I.F.5
Tomashevsky, M.6
Marshall, K.A.7
Phillippy, K.H.8
Sherman, P.M.9
Holko, M.10
-
26
-
-
77955287813
-
An overview of MetaMap: Historical perspective and recent advances
-
Aronson,A.R. and Lang,F.-M. (2010) An overview of MetaMap: historical perspective and recent advances. J. Am. Med. Inform. Assoc., 17, 229-236.
-
(2010)
J. Am. Med. Inform. Assoc.
, vol.17
, pp. 229-236
-
-
Aronson, A.R.1
Lang, F.-M.2
-
27
-
-
84891790401
-
The NHGRI GWAS Catalog, a curated resource of SNP-trait associations
-
Welter,D., MacArthur,J., Morales,J., Burdett,T., Hall,P., Junkins,H., Klemm,A., Flicek,P., Manolio,T., Hindorff,L. et al. (2014) The NHGRI GWAS Catalog, a curated resource of SNP-trait associations. Nucleic Acids Res., 42, D1001-D1006.
-
(2014)
Nucleic Acids Res.
, vol.42
-
-
Welter, D.1
Macarthur, J.2
Morales, J.3
Burdett, T.4
Hall, P.5
Junkins, H.6
Klemm, A.7
Flicek, P.8
Manolio, T.9
Hindorff, L.10
-
28
-
-
78651287426
-
DrugBank 3.0: A comprehensive resource for "omics" research on drugs
-
Knox,C., Law,V., Jewison,T., Liu,P., Ly,S., Frolkis,A., Pon,A., Banco,K., Mak,C., Neveu,V. et al. (2011) DrugBank 3.0: a comprehensive resource for "omics" research on drugs. Nucleic Acids Res., 39, D1035-D1041.
-
(2011)
Nucleic Acids Res.
, vol.39
-
-
Knox, C.1
Law, V.2
Jewison, T.3
Liu, P.4
Ly, S.5
Frolkis, A.6
Pon, A.7
Banco, K.8
Mak, C.9
Neveu, V.10
-
29
-
-
12144290446
-
GeneWays: A system for extracting, analyzing, visualizing, and integrating molecular pathway data
-
Rzhetsky,A., Iossifov,I., Koike,T., Krauthammer,M., Kra,P., Morris,M., Yu,H., Duboué,P.A., Weng,W., Wilbur,W.J. et al. (2004) GeneWays: a system for extracting, analyzing, visualizing, and integrating molecular pathway data. J. Biomed. Inform., 37, 43-53.
-
(2004)
J. Biomed. Inform.
, vol.37
, pp. 43-53
-
-
Rzhetsky, A.1
Iossifov, I.2
Koike, T.3
Krauthammer, M.4
Kra, P.5
Morris, M.6
Yu, H.7
Duboué, P.A.8
Weng, W.9
Wilbur, W.J.10
-
30
-
-
84904820421
-
-
OMIM - Online Mendelian Inheritance in Man
-
OMIM - Online Mendelian Inheritance in Man (http://www.omim.org/).
-
-
-
-
31
-
-
0037012880
-
Specificity and stability in topology of protein networks
-
Maslov,S. and Sneppen,K. (2002) Specificity and stability in topology of protein networks. Science, 296, 910-913.
-
(2002)
Science
, vol.296
, pp. 910-913
-
-
Maslov, S.1
Sneppen, K.2
-
32
-
-
13444266370
-
Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders
-
Hamosh,A., Scott,A.F., Amberger,J.S., Bocchini,C.A. and McKusick,V.A. (2005) Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders. Nucleic Acids Res., 33, D514-D517.
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Hamosh, A.1
Scott, A.F.2
Amberger, J.S.3
Bocchini, C.A.4
McKusick, V.A.5
-
33
-
-
78650373804
-
Network medicine: A network-based approach to human disease
-
Barabási,A.-L., Gulbahce,N. and Loscalzo,J. (2011) Network medicine: a network-based approach to human disease. Nat. Rev. Genet., 12, 56-68.
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 56-68
-
-
Barabási, A.-L.1
Gulbahce, N.2
Loscalzo, J.3
-
34
-
-
29144474447
-
Mining coherent dense subgraphs across massive biological networks for functional discovery
-
Hu,H., Yan,X., Huang,Y., Han,J. and Zhou,X.J. (2005) Mining coherent dense subgraphs across massive biological networks for functional discovery. Bioinformatics, 21(Suppl. 1), i213-221.
-
(2005)
Bioinformatics
, vol.21
, Issue.SUPPL. 1
-
-
Hu, H.1
Yan, X.2
Huang, Y.3
Han, J.4
Zhou, X.J.5
-
35
-
-
0034649696
-
Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia.N
-
Rai,K.R., Peterson,B.L., Appelbaum,F.R., Kolitz,J., Elias,L., Shepherd,L., Hines,J., Threatte,G.A., Larson,R.A., Cheson,B.D. et al. (2000) Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia.N. Engl. J. Med., 343, 1750-1757.
-
(2000)
Engl. J. Med.
, vol.343
, pp. 1750-1757
-
-
Rai, K.R.1
Peterson, B.L.2
Appelbaum, F.R.3
Kolitz, J.4
Elias, L.5
Shepherd, L.6
Hines, J.7
Threatte, G.A.8
Larson, R.A.9
Cheson, B.D.10
-
36
-
-
84880697237
-
Phase II clinical trial for the evaluation of bortezomib within the reduced intensity conditioning regimen (RIC) and post-allogeneic transplantation for high-risk myeloma patients
-
Caballero-Velázquez,T., López-Corral,L., Encinas,C., Castilla-Llorente,C., Martino,R., Rosiñol,L., Sampol,A., Caballero,D., Serrano,D., Heras,I. et al. (2013) Phase II clinical trial for the evaluation of bortezomib within the reduced intensity conditioning regimen (RIC) and post-allogeneic transplantation for high-risk myeloma patients. Br. J. Haematol., 162, 474-482.
-
(2013)
Br. J. Haematol.
, vol.162
, pp. 474-482
-
-
Caballero-Velázquez, T.1
López-Corral, L.2
Encinas, C.3
Castilla-Llorente, C.4
Martino, R.5
Rosiñol, L.6
Sampol, A.7
Caballero, D.8
Serrano, D.9
Heras, I.10
-
37
-
-
84869081811
-
Fludarabine, busulfan, antithymocyte globulin, and total body irradiation for pretransplantation conditioning in acute lymphoblastic leukemia: Excellent outcomes in all but older patients with comorbidities
-
Daly,A., Savoie,M.L., Geddes,M., Chaudhry,A., Stewart,D., Duggan,P., Bahlis,N., Storek,J., Brown,C., Shafey,M. et al. (2012) Fludarabine, busulfan, antithymocyte globulin, and total body irradiation for pretransplantation conditioning in acute lymphoblastic leukemia: excellent outcomes in all but older patients with comorbidities. Biol. Blood Marrow Transplant., 18, 1921-1926.
-
(2012)
Biol. Blood Marrow Transplant.
, vol.18
, pp. 1921-1926
-
-
Daly, A.1
Savoie, M.L.2
Geddes, M.3
Chaudhry, A.4
Stewart, D.5
Duggan, P.6
Bahlis, N.7
Storek, J.8
Brown, C.9
Shafey, M.10
-
38
-
-
0018825033
-
Case mix definition by diagnosis-related groups
-
iii
-
Fetter,R.B., Shin,Y., Freeman,J.L., Averill,R.F. and Thompson,J.D. (1980) Case mix definition by diagnosis-related groups. Med. Care, 18, iii, 1-53.
-
(1980)
Med. Care
, vol.18
, pp. 1-53
-
-
Fetter, R.B.1
Shin, Y.2
Freeman, J.L.3
Averill, R.F.4
Thompson, J.D.5
-
39
-
-
77955712506
-
Bortezomib-resistant myeloma cell lines: A role for mutated PSMB5 in preventing the accumulation of unfolded proteins and fatal ER stress
-
Ri,M., Iida,S., Nakashima,T.,Miyazaki,H., Mori,F., Ito,A., Inagaki,A., Kusumoto,S., Ishida,T., Komatsu,H. et al. (2010) Bortezomib-resistant myeloma cell lines: a role for mutated PSMB5 in preventing the accumulation of unfolded proteins and fatal ER stress. Leukemia, 24, 1506-1512.
-
(2010)
Leukemia
, vol.24
, pp. 1506-1512
-
-
Ri, M.1
Iida, S.2
Nakashima, T.3
Miyazaki, H.4
Mori, F.5
Ito, A.6
Inagaki, A.7
Kusumoto, S.8
Ishida, T.9
Komatsu, H.10
-
40
-
-
34247897136
-
Proteasomal inhibition in intracerebral hemorrhage: Neuroprotective and anti-inflammatory effects of bortezomib
-
Sinn,D.-I., Lee,S.-T., Chu,K., Jung,K.-H., Kim,E.-H., Kim,J.-M., Park,D.-K., Song,E.-C., Kim,B.-S., Yoon,S.-S. et al. (2007) Proteasomal inhibition in intracerebral hemorrhage: neuroprotective and anti-inflammatory effects of bortezomib. Neurosci. Res., 58, 12-18.
-
(2007)
Neurosci. Res.
, vol.58
, pp. 12-18
-
-
Sinn, D.-I.1
Lee, S.-T.2
Chu, K.3
Jung, K.-H.4
Kim, E.-H.5
Kim, J.-M.6
Park, D.-K.7
Song, E.-C.8
Kim, B.-S.9
Yoon, S.-S.10
-
41
-
-
2542593141
-
Thalidomide
-
Franks,M.E., Macpherson,G.R. and Figg,W.D. (2004) Thalidomide. Lancet, 363, 1802-1811.
-
(2004)
Lancet
, vol.363
, pp. 1802-1811
-
-
Franks, M.E.1
Macpherson, G.R.2
Figg, W.D.3
-
42
-
-
84904507572
-
Adalimumab for Crohn's disease: Long-term sustained benefit in a population-based cohort of 438 patients
-
doi:10.1016/j.crohns.2014.01.012
-
Peters,C.P., Eshuis,E.J., Toxopeüs,F.M., Hellemons,M.E., Jansen,J.M., D'Haens,G.R.A.M., Fockens,P., Stokkers,P.C.F., Tuynman,H.A.R.E., van Bodegraven,A.A. et al. (2014) Adalimumab for Crohn's disease: Long-term sustained benefit in a population-based cohort of 438 patients. J. Crohns. Colitis, doi:10.1016/j.crohns.2014.01.012.
-
(2014)
J. Crohns. Colitis
-
-
Peters, C.P.1
Eshuis, E.J.2
Toxopeüs, F.M.3
Hellemons, M.E.4
Jansen, J.M.5
D'haens, G.R.A.M.6
Fockens, P.7
Stokkers, P.C.F.8
Tuynman, H.A.R.E.9
Van Bodegraven, A.A.10
|