Multiclass method for the determination of quinolones and β-lactams, in raw cow milk using dispersive liquid-liquid microextraction and ultra high performance liquid chromatography-tandem mass spectrometry

Journal of Chromatography A

Volumn 1356, Issue , 2014, Pages 10-22

  Junza, Alexandra ^a   Dorival García, Noemí ^b   Zafra Gómez, Alberto ^b   Barrón, Dolores ^a   Ballesteros, Oscar ^b   Barbosa, José ^a   Navalón, Alberto ^b  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSITY OF GRANADA   (Spain)

Author keywords

Cephalosporins; DLLME; Penicillins; Quinolones; Raw milk analysis; UHPLC MS MS

Indexed keywords

AMIDES; ANTIBIOTICS; CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LAWS AND LEGISLATION; MASS SPECTROMETRY; SEWAGE TREATMENT PLANTS;

CEPHALOSPORINS; DLLME; PENICILLINS; QUINOLONES; RAW MILK; U-HPLC-MS;

SOLVENT EXTRACTION;

AMOXICILLIN; BETA LACTAM; CAFFEINE; CEFALEXIN; CEFAPIRIN; CEFAZOLIN; CEFOPERAZONE; CEFTIOFUR; CINCHOPHEN; CINOXACIN; CIPROFLOXACIN; CLOXACILLIN; DANOFLOXACIN; DIFLOXACIN; ENOXACIN; ENROFLOXACIN; FLUMEQUINE; LOMEFLOXACIN; MARBOFLOXACIN; NAFCILLIN; NALIDIXIC ACID; NORDIFLOXACIN; NORFLOXACIN; OFLOXACIN; OXACILLIN; OXOLINIC ACID; PIPEMIDIC ACID; PIROMIDIC ACID; QUINOLONE DERIVATIVE; UNINDEXED DRUG;

ACCURACY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG STRUCTURE; LIMIT OF QUANTITATION; LIQUID PHASE MICROEXTRACTION; MILK; NONHUMAN; PH; PHYSICAL PARAMETERS; PRIORITY JOURNAL; PROCESS OPTIMIZATION; SENSITIVITY ANALYSIS; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; VALIDATION STUDY;

CEPHALOSPORINS; DLLME; PENICILLINS; QUINOLONES; RAW MILK ANALYSIS; UHPLC-MS/MS;

ACETONITRILES; ANIMALS; ANTI-BACTERIAL AGENTS; CATTLE; CEPHALOSPORINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; HYDROGEN-ION CONCENTRATION; LIQUID PHASE MICROEXTRACTION; MILK; PENICILLINS; QUINOLONES; SOLVENTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84904767897     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2014.06.034     Document Type: Article

References (43)

1. European Parliament and the Council Regulation No 1831/2003 of the 22 September 2003 on additives for use in animal nutrition. Off. J. Eur. Comm. 2003, L268/29-L268/68.
2. Commission of the European Communities Regulation No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin. Off. J. Eur. Comm. 2009, L15/1-L15/5.
3. Jank L., Hoff R.B., Torouco P.C., Barreto F., Pizzolato T.M. β-lactam antibiotics residues analysis in bovine milk by LC-ESI-MS/MS: a simple and fast liquid-liquid extraction method. Food Addit. Contam. 2012, 29:497-507.
4. Junza A., Amatya R., Barrón D., Barbosa J. Comparative study of the LC-MS/MS and UPLC-MS/MS for the multi-residue analysis of quinolones, penicillins and cephalosporins in cow milk, and validation according to the regulation 2002/657/EC. J. Chromatogr. B 2011, 879:2601-2610.
5. Macarov C.A., Tong L., Martínez-Huélamo M., Hermo M.P., Chirila E., Wang Y.X., Barrón D., Barbosa J. Multi residue determination of the penicillins regulated by the European Union, in bovine, porcine and chicken muscle, by LC-MS/MS. Food Chem. 2012, 135:2612-2621.
6. Wen Y., Wang Y., Feng Y.Q. Simultaneous residue monitoring of four tetracycline antibiotics in fish muscle by in-tube solid-phase microextraction coupled with high-performance liquid chromatography. Talanta 2006, 70:153-159.
7. Huang J.F., Lin B., Yu Q.W., Feng Y.Q. Determination of fluoroquinolones in eggs using in-tube solid-phase microextraction coupled to high-performance liquid chromatography. Anal. Bioanal. Chem. 2006, 384:1228-1235.
8. Quesada-Molina C., Claude B., García-Campaña A.M., del Olmo-Iruela M., Morin P. Convenient solid phase extraction of cephalosporins in milk using a molecularly imprinted polymer. Food Chem. 2012, 135:775-779.
9. Jing T., Niu J., Xia H., Dai Q., Zheng H., Hao Q., Mei S., Zhou Y. Online coupling of molecularly imprinted solid-phase extraction to HPLC for determination of trace tetracycline antibiotic residues in egg samples. J. Sep. Sci. 2011, 34:1469-1476.
10. Blasco C., Di Corcia A., Picó Y. Determination of tetracyclines in multi-specie animal tissues by pressurized liquid extraction and liquid chromatography-tandem mass spectrometry. Food Chem. 2009, 116:1005-1012.
11. Pérez-Burgos R., Grzelak E.M., Gakce G., Saurina J., Barbosa J., Barrón D. Quechers methodologies as an alternative to solid phase extraction (SPE) for the determination and characterization of residues of cephalosporins in beef muscle using LC-MS/MS. J. Chromatogr. B 2012, 899:57-65.
12. Yan H., Wang H. Recent development and applications of dispersive liquid-liquid microextraction. J. Chromatogr. A 2013, 1295:1-15.
13. Daneshfar A., Khezeli T., Lotfi H.J. Determination of cholesterol in food samples using dispersive liquid-liquid microextraction followed by HPLC-UV. J. Chromatogr. B 2009, 877:456-460.
14. Moema D., Nindi M.M., Dube S. Development of a dispersive liquid-liquid microextraction method for the determination of fluoroquinolones in chicken liver by high performance liquid chromatography. Anal. Chim. Acta 2012, 730:80-86.
15. Tsai W.H., Chuang H.Y., Chen H.H., Huang J.J., Chen H.C., Cheng S.H., Huang T.C. Application of dispersive liquid-liquid microextraction and dispersive micro-solid-phase extraction for the determination of quinolones in swine muscle by high-performance liquid chromatography with diode-array detection. Anal. Chim. Acta 2009, 656:56-62.
16. Liu B., Yan H., Qiao F., Geng Y. Determination of clenbuterol in porcine tissues using solid-phase extraction combined with ultrasound-assisted dispersive liquid-liquid microextraction and HPLC-UV detection. J. Chromatogr. B 2011, 879:90-94.
17. Campillo N., Viñas P., Férez-Melgarejo G., Hernández-Córdoba M. Dispersive liquid-liquid microextraction for the determination of macrocyclic lactones in milk by liquid chromatography with diode array detection and atmospheric pressure chemical ionization ion-trap tandem mass spectrometry. J. Chromatogr. A 2013, 1282:20-26.
18. Alshana U., Goger N.G., Ertas N. Dispersive liquid-liquid microextraction combined with field-amplified sample stacking in capillary electrophoresis for the determination of non-steroidal anti-inflammatory drugs in milk and dairy products. Food Chem. 2013, 138:890-897.
19. Campone L., Piccinelli A.L., Celano R., Russo M., Rastrelli L. Rapid analysis of aflatoxin M1 in milk using dispersive liquid-liquid microextraction coupled with ultrahigh pressure liquid chromatography tandem mass spectrometry. Anal. Bioanal. Chem. 2013, 405:8645-8652.
20. Xu X., Su R., Zhao X., Liu Z., Zhang Y., Li D., Li X., Zhang H., Wang Z. Ionic liquid-based microwave-assisted dispersive liquid-liquid microextraction and derivatization of sulfonamides in river water, honey, milk, and animal plasma. Anal. Chim. Acta 2011, 707:92-99.
21. Arroyo-Manzanares N., Gámiz-Gracia L., García-Campaña A.M. Alternative sample treatments for the determination of sulfonamides in milk by HPLC with fluorescence detection. Food Chem. 2014, 143:459-464.
22. Gao S., Jin H., You J., Ding Y., Zhang N., Wang Y., Ren R., Zhang R., Zhang H. Ionic liquid-based homogeneous liquid-liquid microextraction for the determination of antibiotics in milk by high-performance liquid chromatography. J. Chromatogr. A 2011, 1218:7254-7263.
23. Adlnasab L., Ebrahimzadeh H., Yamini Y. A three phase dispersive liquid-liquid microextraction technique for the extraction of antibiotics in milk. Microchim. Acta 2012, 179:179-184.
24. Commission of the European Communities Decision 2002/657/EC of 12 August 2002 implementing Council Directive 96/23/EC concerning the performance of analytical methods and the interpretation of results. Off. J. Eur. Comm. 2002, L221/8-L221/21.
25. U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER), Center for Veterinary Medicine (CVM) Bioanalytical Method Validation, Guidance for Industry 2001, 1-22.
26. Tamtam F., Mercier F., Eurin J., Chevreuil M., Le Bot B. Ultra performance liquid chromatography tandem mass spectrometry performance evaluation for analysis of antibiotics in natural waters. Anal. Bioanal. Chem. 2009, 393:1709-1718.
27. Volmer D.A., Mansoori B., Locke S.J. Study of 4-quinolone antibiotics in biological samples by short-column liquid chromatography coupled with electrospray ionization tandem mass spectrometry. Anal. Chem. 1997, 69:4143-4155.
28. a values of quinolones from mobility and spectroscopic data obtained by CE and DAD. Anal. Chim. Acta 2002, 464:37-45.
29. Hu J., Wang W., Zhu Z., Chang H., Pan F., Lin B. Quantitative structure-activity relationship model for prediction of genotoxic potential for quinolone antibacterials. Environ. Sci. Technol. 2007, 41:4806-4813.
30. Alekseev V.G. Acid-base properties of penicillins and cephalosporins (a review). Pharm. Chem. J. 2010, 44:14-24.
31. Li B., Zhang T., Xu Z., Fang H.H.P. Rapid analysis of 21 antibiotics of multiple classes in municipal wastewater using ultra performance liquid chromatography-tandem mass spectrometry. Anal. Chim. Acta. 2009, 645:64-72.
32. Chong X., Hu C. Compilation of an ES-MS library of β-lactam antibiotics for rapid identification of drugs. Chromatographia 2008, 68:759-766.
33. Parrilla Vázquez M.D.M., Parrilla Vázquez P., Martínez Galera M., Molina Sánchez L. Simple, rapid, and sensitive determination of beta-blockers in environmental water using dispersive liquid-liquid microextraction followed by liquid chromatography with fluorescence detection. J. Sep. Sci. 2012, 35:2184-2192.
34. Guo J.H., Li X.H., Cao X.L., Li Y., Wang X.Z., Xu X.B. Determination of triclosan, triclocarban and methyl-triclosan in aqueous samples by dispersive liquid-liquid microextraction combined with rapid liquid chromatography. J. Chromatogr. A 2009, 1216:3038-3043.
35. Hassam S., Maryam K., Soheila S. Application of response surface method for optimization of dispersive liquid-liquid microextraction of water-soluble components of Rosa damascena Mill. J. Chromatogr. A 2009, 1216:198-204.
36. Herrera-Herrera A.V., Hernández-Borges J., Borges-Miquel T.M., Rodríguez-Delgado M.A. Dispersive liquid-liquid microextraction combined with ultra-high performance liquid chromatography for the simultaneous determination of 25 sulfonamide and quinolone antibiotics in water samples. J. Pharm. Biomed. Anal. 2013, 75:130-137.
37. Park H., Kim T., Bark K. Physicochemical properties of quinolone antibiotics in various environments. Eur. J. Med. Chem. 2002, 37:443-460.
38. Irwin V.P., Quigley J.M., Timoney R.F. Quantitative relationships between in vitro antibacterial activities of cephalosporins and their n-octanol/water partition coefficients. Int. J. Pharm. 1987, 34:241-246.
39. Chambers H.F., Moreau D., Yajko D., Miick C., Wagner C., Hackbarth C., Kocagöz S., Rosenberg E., Hadley W.K., Nikaido H. Can penicillins and other beta-lactam antibiotics be used to treat tuberculosis?. Antimicrob. Agents Chemother. 1995, 39:2620-2624.
40. a values of active pharmaceutical ingredients. Trends Anal. Chem. 2007, 26:1043-1061.
41. Msagati T.A.M., Nindi M.M. Determination of β-lactam residues in foodstuffs of animal origin using supported liquid membrane extraction and liquid chromatography-mass spectrometry. Food Chem. 2007, 100:836-844.
42. Gandhi S., Rajput S. Study of degradation profile and development of stability indicating methods for cefixime trihydrate. Indian J. Pharm. Sci. 2009, 71:438-442.
43. Analytical Methods Committee Is my calibration linear?. Analyst 1994, 119:2363-2366.