Dehydroascorbic acid taken up by glucose transporters stimulates estradiol production through inhibition of JNK/c-Jun/AP1 signaling in JAR cells

Molecular Human Reproduction

Volumn 20, Issue 8, 2014, Pages

  Wang, Yongjie ^a   Tang, Chao ^a   Wu, Minglan ^a   Pan, Yibin ^a   Ruan, Hhongfeng ^a   Chen, Linling ^a   Yao, Hongyi ^a   Zhu, Haibin ^b   Wu, Ximei ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Ap1; Dehydroascorbic acid; Estradiol; JNK; Trophoblasts

Indexed keywords

17BETA HYDROXYSTEROID DEHYDROGENASE TYPE 1; 3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; 3BETA HYDROXYSTEROID DEHYDROGENASE 1; ALPHA TOCOPHEROL; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; AROMATASE; CYTOCHROME P450; DEHYDROASCORBIC ACID; DEOXYGLUCOSE; DIETHYLMALEATE; ESTRADIOL; GLUCOSE TRANSPORTER; LUCIFERASE; MALEIC ACID; MESSENGER RNA; PROGESTERONE; PROTEIN C JUN; SHORT HAIRPIN RNA; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TRIPHENYLTETRAZOLIUM; UNCLASSIFIED DRUG; 3 (OR 17)-BETA-HYDROXYSTEROID DEHYDROGENASE; HYDROXYSTEROID DEHYDROGENASE; PHLORETIN;

ARTICLE; CELL LINE; CHORIOCARCINOMA CELL LINE; CONTROLLED STUDY; CYTOTROPHOBLAST; DOSE RESPONSE; ENZYME IMMUNOASSAY; ENZYME INHIBITION; ESTRADIOL BLOOD LEVEL; ESTROGEN SYNTHESIS; FEMALE; GENE SILENCING; HUMAN; HUMAN CELL; JAR CELL LINE; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; STEROIDOGENESIS; WESTERN BLOTTING; CHORIOCARCINOMA; DRUG EFFECTS; METABOLISM; PHYSIOLOGY; TROPHOBLAST; TUMOR CELL LINE;

17-HYDROXYSTEROID DEHYDROGENASES; 3-HYDROXYSTEROID DEHYDROGENASES; AROMATASE; CELL LINE, TUMOR; CHORIOCARCINOMA; DEHYDROASCORBIC ACID; DEOXYGLUCOSE; ESTRADIOL; HUMANS; MAP KINASE SIGNALING SYSTEM; PHLORETIN; PROTO-ONCOGENE PROTEINS C-JUN; TROPHOBLASTS;

EID: 84904731932     PISSN: 13609947     EISSN: 14602407     Source Type: Journal    
DOI: 10.1093/molehr/gau036     Document Type: Article

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