Ascorbic acid uptaken by sodium-dependent vitamin C transporter 2 induces βhCG expression through Sp1 and TFAP2A transcription factors in human choriocarcinoma cells

Journal of Clinical Endocrinology and Metabolism

Volumn 97, Issue 9, 2012, Pages

  Chen, Lihua ^a   Zhu, Haibin ^b   Pan, Yibin ^a,b   Tang, Chao ^a,b   Watanabe, Mai ^c   Ruan, Hongfeng ^a,b   Wang, Yongjie ^a   Wang, Jirong ^a   Yao, Hong Yi ^a   Iguchi, Takuma ^c   Wu, Ximei ^a,b  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHORIONIC GONADOTROPIN BETA SUBUNIT; CHORIONIC GONADOTROPIN BETA SUBUNIT 5; MESSENGER RNA; SHORT HAIRPIN RNA; SODIUM ASCORBIC ACID COTRANSPORTER; SODIUM ASCORBIC ACID COTRANSPORTER 1; SODIUM ASCORBIC ACID COTRANSPORTER 2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ACTIVATING ENHANCER BINDING PROTEIN 2A; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

ARTICLE; BHCG GENE; CARCINOMA CELL; CHORIOCARCINOMA; CONTROLLED STUDY; CYTOTROPHOBLAST; ENZYME ACTIVITY; FEMALE; GENE DELETION; GENE SEQUENCE; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; ONCOGENE; PLACENTA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REPORTER GENE; RETROVIRUS; TRANSACTIVATION;

ADULT; ASCORBIC ACID; BLOTTING, WESTERN; CELL LINE, TUMOR; CHORIOCARCINOMA; CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN; CYCLIC AMP; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC VECTORS; HUMANS; PLACENTA; PLASMIDS; PREGNANCY; REAL-TIME POLYMERASE CHAIN REACTION; RETROVIRIDAE; RNA, MESSENGER; RNA, SMALL INTERFERING; SODIUM-COUPLED VITAMIN C TRANSPORTERS; SP1 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP-2;

EID: 84866181999     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2012-1753     Document Type: Article

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