Co-precipitation of tobramycin into biomimetically coated orthopedic fixation pins employing submicron-thin seed layers of hydroxyapatite

Current Drug Delivery

Volumn 11, Issue 4, 2014, Pages 501-510

  Sörensen, Jan H ^a   Lilja, Mirjam ^b,c   Åstrand, Maria ^c   Sörensen, Torben C ^d   Procter, Philip ^e   Strømme, Maria ^b   Steckel, Hartwig ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b UPPSALA UNIVERSITY   (Sweden)

^c AB Sandvik Coromant   (Sweden)

^d Stryker Orthopaedics   (United States)

^e Stryker Osteosynthesis AG   (Switzerland)

Author keywords

Biomimetic coating; Co precipitation; Drug release; Hydroxyapatite; Tobramycin

Indexed keywords

BIOMIMETIC MATERIAL; HYDROXYAPATITE; TOBRAMYCIN; ANTIINFECTIVE AGENT; DELAYED RELEASE FORMULATION; TITANIUM; TITANIUM DIOXIDE;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL COLONIZATION; BONE PIN; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG RELEASE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MATERIAL COATING; MORPHOLOGY; PRECIPITATION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TEMPERATURE; THICKNESS; ADMINISTRATION AND DOSAGE; BACTERIAL INFECTIONS; BONE NAIL; CHEMISTRY; COMPARATIVE STUDY; CROSS INFECTION; DELAYED RELEASE FORMULATION; DRUG DELIVERY SYSTEM; HEAT; HUMAN; INTERNAL FIXATOR; KINETICS; METABOLISM; OSMOLARITY; SOLUBILITY; SURFACE PROPERTY; SURGICAL WOUND INFECTION; THERAPEUTIC USE;

ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; BIOMIMETIC MATERIALS; BONE NAILS; CHEMICAL PRECIPITATION; CROSS INFECTION; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; DURAPATITE; HOT TEMPERATURE; HUMANS; INTERNAL FIXATORS; KINETICS; MICROSCOPY, ELECTRON, SCANNING; OSMOLAR CONCENTRATION; SOLUBILITY; SURFACE PROPERTIES; SURGICAL WOUND INFECTION; TITANIUM; TOBRAMYCIN;

EID: 84904731756     PISSN: 15672018     EISSN: 18755704     Source Type: Journal    
DOI: 10.2174/1567201811666140311154104     Document Type: Article

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