In vitro characterization of bioactive titanium dioxide/hydroxyapatite surfaces functionalized with BMP-2

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 91, Issue 2, 2009, Pages 780-787

  Piskounova, Sonya ^a   Forsgren, Johan ^a   Brohede, Ulrika ^a   Engqvist, Håkan ^a   Strømme, Maria ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Anatase titanium dioxide; Biomimetic hydroxyapatite; BMP 2; Differentiation; Growth factors; Mesenchymal stem cells; Morphology; Viability

Indexed keywords

ACTIVE MOLECULES; ANATASE TITANIUM DIOXIDE; BIOACTIVE TITANIUM; BONE MORPHOGENETIC PROTEIN-2; BONE RESORPTION; CELL BEHAVIORS; CELL DIFFERENTIATION; CELL MORPHOLOGY; CELL VIABILITY; CRYSTALLINE TITANIUM DIOXIDE; FUNCTIONALIZED; GROWTH FACTOR; GROWTH FACTORS; IMPLANT FIXATION; IN-VITRO; INNER LAYER; MESENCHYMAL STEM CELL; OSSEOINTEGRATION; OSTEOCONDUCTIVE; OUTER LAYER; TIO;

APATITE; BIOACTIVITY; BIOMIMETICS; BONE; CELL CULTURE; CRYSTALLINE MATERIALS; HYDROXYAPATITE; HYDROXYLATION; MORPHOLOGY; PEPTIDES; TITANIUM; TITANIUM DIOXIDE; TITANIUM OXIDES;

CELLS;

BIOMIMETIC MATERIAL; BONE MORPHOGENETIC PROTEIN 2; HYDROXYAPATITE; TITANIUM DIOXIDE;

ARTICLE; BONE CONDUCTION; BONE REGENERATION; CELL CULTURE; CELL DIFFERENTIATION; CELL FUNCTION; CELL STRUCTURE; CELL VIABILITY; HUMAN; HUMAN CELL; IMPLANT; IN VITRO STUDY; MATERIAL COATING; MESENCHYMAL STEM CELL;

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; CELL DIFFERENTIATION; CELL SURVIVAL; COATED MATERIALS, BIOCOMPATIBLE; DURAPATITE; HUMANS; MESENCHYMAL STEM CELLS; MICROSCOPY, ELECTRON, SCANNING; OXYGEN; STERILIZATION; SURFACE PROPERTIES; TITANIUM; X-RAY DIFFRACTION;

EID: 71649095367     PISSN: 15524973     EISSN: 15524981     Source Type: Journal    
DOI: 10.1002/jbm.b.31456     Document Type: Article

References (65)

1. Cheng GJ, Pirzada D, Cai M, Mohanty P, Bandyopadhyay A. Bioceramic coating of hydroxyapatite on titanium substrate with Nd-YAG laser. Mater Sci Eng C 2005;25:541-547. (Pubitemid 41084232)
2. Barrere F, Mahmood TA, de Groot K, van Blitterswijk CA. Advanced biomaterials for skeletal tissue regeneration: Instructive and smart functions. Mater Sci Eng R 2008;59:38-71. (Pubitemid 351625615)
3. Hench LL. (ii) The challenge of orthopaedic materials. Curr Orthopaed 2000;14:7-15.
4. Hench LL. Biomaterials: A Forecast for the Future. Strasbourg, France: Elsevier Science. pp 1419-1423.
5. Krishna BV, Bose S, Bandyopadhyay A. Low stiffness porous Ti structures for load-bearing implants. Acta Biomater 2007; 3:997-1006. (Pubitemid 47382664)
6. Heisel C, Silva M, Schmalzried TP. Bearing surface options for total hip replacement in young patients. J Bone Joint Surg Am A 2003;85:1366-1379. (Pubitemid 36764948)
7. Ingham E, Fisher J. The role of macrophages in osteolysis of total joint replacement. Biomaterials 2005;26:1271-1286. (Pubitemid 39314501)
8. Katzer A, Loehr JF. Early loosening of hip replacements: Causes, course and diagnosis. J Orthop Traumatol 2003;4: 105-116. (Pubitemid 38088822)
9. Ryd L, Albrektsson BEJ, Carlsson L, Dansgard F, Herberts P, Lindstrand A, Regner L, Toksviglarsen S. Roentgen stereophotogrammetric analysis as a predictor of mechanical loosening of knee prostheses. J Bone Joint Surg Br B 1995;77:377-383.
10. Amstutz HC, Campbell P, Kossovsky N, Clarke IC. Mechanism and clinical-significance of wear debris-induced osteolysis. Clin Orthop Relat Res 1992;276:7-18.
11. Gelb H, Schumacher HR, Cuckler J, Baker DG. In-vivo inflammatory response to polymethylmethacrylat particulate debris-effect of size, morphology, and surface-area. J Orthop Res 1994;12:83-92. (Pubitemid 24070792)
12. Le GuÈhennec L, Soueidan A, Layrolle P, Amouriq Y. Surface treatments of titanium dental implants for rapid osseointegration. Dent Mater 2007;23:844-854. (Pubitemid 46734313)
13. Ryan G, Pandit A, Apatsidis DP. Fabrication methods of porous metals for use in orthopaedic applications. Biomaterials 2006;27:2651-2670. (Pubitemid 43122070)
14. Jinno T, Kirk SK, Morita S, Goldberg VM. Effects of calcium ion implantation on osseointegration of surface-blasted titanium alloy femoral implants in a canine total hip arthroplasty model. J Arthroplasty 2004;19:102-109. (Pubitemid 38112339)
15. Morra M. Biochemical modification of titanium surfaces: Peptides and ECM proteins. Eur Cell Mater 2006;12:1-15. (Pubitemid 44898107)
16. Best SM, Porter AE, Thian ES, Huang J. Bioceramics: Past, present and for the future. J Eur Ceram Soc 2008;28:1319-1327.
17. Hench LL. Bioceramics. J Am Ceram Soc 1998;81:1705-1728.
18. Sun LM, Berndt CC, Gross KA, Kucuk A. Material fundamentals and clinical performance of plasma-sprayed hydroxyapatite coatings: A review. J Biomed Mater Res 2001;58:570-592. (Pubitemid 32899914)
19. Ducheyne P, Lemons J. Bioceramics: Material characteristics versus in vivo behaviour. New York: New York Academy of Science; 1988.
20. Kokubo T, Takadama H. How useful is SBF in predicting in vivo bone bioactivity? Biomaterials 2006;27:2907-2915.
21. Hench LL. The story of Bioglass (R). J Mater Sci Mater Med 2006;17:967-978.
22. Vallet-Regi M, Gonzalez-Calbet JM. Calcium phosphates as substitution of bone tissues. Prog Solid State Chem 2004; 32:1-31.
23. Lindberg F, Heinrichs J, Ericson F, Thomsen P, Engqvist H. Hydroxylapatite growth on single-crystal rutile substrates. Biomaterials 2008;29:3317-3323.
24. Ha SW, Mayer J, Koch B, Wintermantel E. Plasma-sprayed hydroxylapatite coating on carbon-fiber-reinforced thermoplastic composite-materials. J Mater Sci Mater Med 1994;5:481-484. (Pubitemid 24338718)
25. Blind O, Klein LH, Dailey B, Jordan L. Characterization of hydroxyapatite films obtained by pulsed-laser deposition on Ti and Ti-6AL-4v substrates. Dent Mater 2005;21:1017-1024. (Pubitemid 41475540)
26. Lee SH, Kim HE, Kim HW. Nano-sized hydroxyapatite coatings on Ti substrate with TiO2 buffer layer by e-beam deposition. J Am Ceram Soc 2007;90:50-56.
27. Jonasova L, Muller FA, Helebrant A, Strnad J, Greil P. Biomimetic apatite formation on chemically treated titanium. Biomaterials 2004;25:1187-1194. (Pubitemid 37476196)
28. Ginebra MP, Traykova T, Planell JA. Calcium phosphate cements as bone drug delivery systems: A review. J Controlled Release 2006;113:102-110. (Pubitemid 44202359)
29. Stigter M, de Groot K, Layrolle P. Incorporation of tobramycin into biomimetic hydroxyapatite coating on titanium. Biomaterials 2002;23:4143-4153. (Pubitemid 34765705)
30. Stigter M, Bezemer J, de Groot K, Layrolle P. Incorporation of different antibiotics into carbonated hydroxyapatite coatings on titanium implants, release and antibiotic efficacy. J Controlled Release 2004;99:127-137. (Pubitemid 39165739)
31. Alt V, Bitschnau A, Österling J, Sewing A, Meyer C, Kraus R, Meissner SA, Wenisch S, Domann E, Schnettler R. The effects of combined gentamicin-hydroxyapatite coating for cementless joint prostheses on the reduction of infection rates in a rabbit infection prophylaxis model. Biomaterials 2006;27: 4627-4634. (Pubitemid 43783227)
32. Liu Y, Huse RO, de Groot K, Buser D, Hunziker EB. Delivery mode and efficacy of BMP-2 in association with implants. J Dent Res 2007;86:84-89.
33. Liu YL, Hunziker EB, Layrolle P, de Bruijn JD, de Groot K. Bone morphogenetic protein 2 incorporated into biomimetic coatings retains its biological activity. Tissue Eng 2004; 10: 101-108. (Pubitemid 38199365)
34. Brohede U, Forsgren J, Roos S, Mihranyan A, Engqvist H, Strømme M. Multifunctional implant coatings providing possibilities for fast antibiotics loading with subsequent slow release. J Mater Sci Mater Med. Doi 10.1007/s10856-009-3749-6.
35. Åberg J, Brohede U, Mihranyan A, Strømme M, Engqvist H. Bisphosphonate incorporation in surgical implant coatings by fast loading and co-precipitation at low drug concentrations. J Mater Sci Mater Med. Doi: 10.1007/s10856-009-3771-8.
36. Hyup Lee J, Ryu H-S, Lee D-S, Sun Hong K, Chang B-S, Lee C-K. Biomechanical and histomorphometric study on the bone-screw interface of bioactive ceramic-coated titanium screws. Biomaterials 2005;26:3249-3257. (Pubitemid 39650943)
37. Jaffe WL, Scott DF. Total hip arthroplasty with hydroxyapatite- coated prostheses. J Bone Joint Surg Am A 1996;78: 1918-1934. (Pubitemid 26428057)
38. Yildirim OS, Aksakal B, Celik H, Vangolu Y, Okur A. An investigation of the effects of hydroxyapatite coatings on the fixation strength of cortical screws. Med Eng Phys 2005; 27:221-228. (Pubitemid 40203382)
39. Landor I, Vavrik P, Sosna A, Jahoda D, Hahn H, Daniel M. Hydroxyapatite porous coating and the osteointegration of the total hip replacement. Arch Orthop Trauma Surg 2007;127: 81-89. (Pubitemid 46165348)
40. Kaneko H, Uchida M, Kim HM, Kokubo T, Nakamura T. Process of apatite formation induced by anatase on titanium metal in simulated body fluid. Bioceramics 14. Zurich-Uetikon: Trans Tech Publications Ltd; 2002. pp 649-652.
41. Yang BC, Uchida M, Kim HM, Zhang XD, Kokubo T. Preparation of bioactive titanium metal via anodic oxidation treatment. Biomaterials 2004;25:1003-1010. (Pubitemid 37393291)
42. Forsgren J, Svahn F, Jarmar T, Engqvist H. Formation and adhesion of biomimetic hydroxyapatite deposited on titanium substrates. Acta Biomater 2007;3:980-984. (Pubitemid 47382663)
43. Svetina M, Ciacchi LC, Sbaizero O, Meriani S, De Vita A. Deposition of calcium ions on rutile (110): A first-principles investigation. Acta Mater 2001;49:2169-2177.
44. Urist MR. Bone - Formation by autoinduction. Science 1965; 150:893-899.
45. Liu Y, Enggist L, Kuffer AF, Buser D, Hunziker EB. The influence of BMP-2 and its mode of delivery on the osteoconductivity of implant surfaces during the early phase of osseointegration. Biomaterials 2007;28:2677-2686. (Pubitemid 46367217)
46. Reddi AH, Cunningham NS. Initiation and promotion of bone differentiation by bone morphogenetic proteins. J Bone Miner Res 1993;8:499-502.
47. Cochran DL, Schenk R, Buser D, Wozney JM, Jones AA. Recombinant human bone morphogenetic: Protein-2 stimulation of bone formation around endosseous dental implants. J Periodontol 1999;70:139-150.
48. Sykaras N, Woody RD, Iacopino AM, Triplett RG, Nunn ME. Osseointegration of dental implants complexed with rhBM-2: A comparative histomorphometric and radiographic evaluation. Int J Oral Maxillofac Implants 2004;19:667-678. (Pubitemid 39430454)
49. Tazaki J, Akazawa T, Murata M, Yamamoto M, Tabata Y, Yoshimoto R, Arisue M. BMP-2 dose-response and release studies in functionally graded HAp. Key Eng Mater 2006;309-311:965-968.
50. Ono I, Tateshita T, Inoue M, Kuboki Y. In vivo strength enhancement of hydroxyapatite combined with rhBMP-2. J Bone Miner Metab 1998;16:81-87.
51. Mosmann T. Rapid colorimetric assay for cellular growth and survival - Application to proliferation and cyto-toxicity assays. J Immunol Meth 1983;65:55-63. (Pubitemid 14203433)
52. Dong XL, Wang Q, Wu T, Pan HH. Understanding adsorption- desorption dynamics of BMP-2 on hydroxyapatite (001) surface. Biophys J 2007;93:750-759.
53. Brohede U, Zhao S, Lindberg F, Mihranyan A, Forsgren J, Strømme M, Engqvist H. A novel graded bioactive high adhesion implant coating. Appl Surf Sci 2009;7723-7728.
54. Forsgren J, Svahn F, Jarmar T, Engqvist H. Structural change of biomimetic hydroxyapatite coatings due to heat treatment. J Appl Biomater Biomech 2007;5:23-27. (Pubitemid 47066317)
55. Bourgeois B, Laboux O, Obadia L, Gauthier O, Betti E, Aguado E, Daculsi G, Bouler JM. Calcium-deficient apatite: A first in vivo study concerning bone ingrowth. J Biomed Mater Res A 2003;65:402-408. (Pubitemid 37517277)
56. Gautier H, Guicheux J, Grimandi G, Faivre-Chauvet A, Daculsi G, Merle C. In vitro influence of apatite-granule-specific area on human growth hormone loading and release. J Biomed Mater Res 1998;40:606-613.
57. Lu X, Leng Y. Theoretical analysis of calcium phosphate precipitation in simulated body fluid. Biomaterials 2005; 26: 1097-1108. (Pubitemid 39307090)
58. Mosmann T. Rapid colorimetric assay for cellular growth and survival - Application to proliferation and cyto-toxicity assays. J Immunol Methods 1983;65:55-63. (Pubitemid 14203433)
59. Bergman K, Engstrand T, Hilborn J, Ossipov D, Piskounova S, Bowden T. Injectable cell-free template for bone-tissue formation. J Biomed Mater Res A. Forthcoming; doi:10.1002/ jbm.a. 32289.
60. Thies RS, Bauduy M, Ashton BA, Kurtzberg L, Wozney JM, Rosen V. Recombinant human bone morphogenetic protein-2 induces osteoblastic differentiation in W-20-17 stromal cells. Endocrinology 1992;130:1318-1324.
61. Cacciafesta P, Hallam KR, Oyedepo CA, Humphris ADL, Miles MJ, Jandt KD. Characterization of ultraflat titanium oxide surfaces. Chem Mater 2002;14:777-789.
62. Mihranyan A, Forsgren J, Strømme M, Engqvist H. Assessing surface area evolution during biomimetic growth of hydroxyapatite coatings. Langmuir 2009;25:1292-1295.
63. He J, Zhou W, Zhou XJ, Zhong XX, Zhang XL, Wan PB, Zhu BS, Chen WT. The anatase phase of nanotopography titania plays an important role on osteoblast cell morphology and proliferation. J Mater Sci Mater Med 2008;19:3465-3472.
64. Vonrecum AF, Vankooten TG. The influence of micro-topography on cellular-response and the implications for silicone implants. J Biomater Sci Polymer Ed 1995;7:181-198.
65. Deligianni DD, Katsala ND, Koutsoukos PG, Missirlis YF. Effect of surface roughness of hydroxyapatite on human bone marrow cell adhesion, proliferation, differentiation and detachment strength. Biomaterials 2001;22:87-96. (Pubitemid 30734455)