Stromal cell-derived factor-1α/C-X-C chemokine receptor type 4 axis promotes endothelial cell barrier integrity via phosphoinositide 3-kinase and rac1 activation

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 34, Issue 8, 2014, Pages 1716-1722

  Kobayashi, Koji ^a   Sato, Kanako ^a   Kida, Taiki ^a   Omori, Keisuke ^a   Hori, Masatoshi ^a   Ozaki, Hiroshi ^a   Murata, Takahisa ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

CXCR4 receptor; Endothelial cells; SDF 1

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 AMINO 6 [2 [[4 (DIETHYLAMINO) 1 METHYLBUTYL]AMINO] 6 METHYL 4 PYRIMIDINYL] 2 METHYLQUINOLINE; ACTIN; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR7; CROTON OIL; DEXTRAN; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; PLERIXAFOR; RAC1 PROTEIN; SMALL INTERFERING RNA; STROMAL CELL DERIVED FACTOR 1ALPHA; THROMBIN;

ANIMAL CELL; ARTICLE; CATTLE; ELECTRIC RESISTANCE; ENDOTHELIUM CELL; EXTRAVASATION; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

CXCR4 RECEPTOR; ENDOTHELIAL CELLS; SDF-1Α;

ACTIN CYTOSKELETON; ANIMALS; CAPILLARY PERMEABILITY; CATTLE; CELL MOVEMENT; CELLS, CULTURED; CHEMOKINE CXCL12; ELECTRIC IMPEDANCE; ENDOTHELIAL CELLS; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MALE; MICE; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RAC1 GTP-BINDING PROTEIN; RECEPTORS, CXCR4; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION;

EID: 84904698393     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.114.303890     Document Type: Article

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