Dietary intake of calcium and phosphorus and serum concentration in relation to the risk of coronary artery calcification in asymptomatic adults

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 34, Issue 8, 2014, Pages 1763-1769

  Kwak, Sang Mi ^a   Kim, Jong Sung ^b,c   Choi, Yuni ^a   Chang, Yoosoo ^a,b   Kwon, Min Jung ^a   Jung, Jin Gyu ^b   Jeong, Chul ^a,b   Ahn, Jiin ^a   Kim, Hyun Soo ^a   Shin, Hocheol ^a   Ryu, Seungho ^a,b  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Chungnam National University   (South Korea)

^c Chungnam National University College of Medicine   (South Korea)

Author keywords

Calcium; Coronary vessels; Phosphorus

Indexed keywords

CALCIUM; PHOSPHORUS; VITAMIN D;

ADULT; ALCOHOL CONSUMPTION; ARTICLE; ASYMPTOMATIC DISEASE; CALCIUM BLOOD LEVEL; CALCIUM INTAKE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CHRONIC KIDNEY DISEASE; COHORT ANALYSIS; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORONARY ARTERY CALCIFICATION; CORONARY ARTERY CALCIUM SCORE; CROSS-SECTIONAL STUDY; DIETARY INTAKE; DISEASE ASSOCIATION; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; KOREAN (PEOPLE); MAJOR CLINICAL STUDY; MALE; PHOSPHATE BLOOD LEVEL; PHOSPHORUS INTAKE; PRIORITY JOURNAL; RISK ASSESSMENT; VITAMIN BLOOD LEVEL;

CALCIUM; CORONARY VESSELS; PHOSPHORUS;

ADULT; ASYMPTOMATIC DISEASES; BIOLOGICAL MARKERS; CALCIUM, DIETARY; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; LINEAR MODELS; MALE; MIDDLE AGED; MULTIDETECTOR COMPUTED TOMOGRAPHY; MULTIVARIATE ANALYSIS; NUTRITION ASSESSMENT; PHOSPHORUS, DIETARY; PREDICTIVE VALUE OF TESTS; PREVALENCE; QUESTIONNAIRES; REPUBLIC OF KOREA; RISK FACTORS; UP-REGULATION; VASCULAR CALCIFICATION;

EID: 84904696863     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.114.303440     Document Type: Article

References (40)

1. Taylor JG, Bushinsky DA. Calcium and phosphorus homeostasis. Blood Purif. 2009;27:387-394.
2. Foley RN, Collins AJ, Herzog CA, Ishani A, Kalra PA. Serum phosphorus levels associate with coronary atherosclerosis in young adults. J Am Soc Nephrol. 2009;20:397-404.
3. Rubin MR, Rundek T, McMahon DJ, Lee HS, Sacco RL, Silverberg SJ. Carotid artery plaque thickness is associated with increased serum calcium levels: the Northern Manhattan study. Atherosclerosis. 2007;194:426-432.
4. Tarrass F, Benjelloun M, Zamd M, Medkouri G, Hachim K, Benghanem MG, Ramdani B. Heart valve calcifications in patients with end-stage renal disease: analysis for risk factors. Nephrology (Carlton). 2006;11:494-496.
5. Shuvy M, Abedat S, Beeri R, Danenberg HD, Planer D, Ben-Dov IZ, Meir K, Sosna J, Lotan C. Uraemic hyperparathyroidism causes a reversible inflammatory process of aortic valve calcification in rats. Cardiovasc Res. 2008;79:492-499.
6. Shin S, Kim KJ, Chang HJ, Cho I, Kim YJ, Choi BW, Rh ee Y, Lim SK, Yang WI, Shim CY, Ha JW, Jang Y, Chung N. Impact of serum calcium and phosphate on coronary atherosclerosis detected by cardiac computed tomography. Eur Heart J. 2012;33:2873-2881.
7. Sabanayagam C, Shankar A. Serum calcium levels and hypertension among U.S. adults. J Clin Hypertens (Greenwich). 2011;13:716-721.
8. Ix JH, De Boer IH, Peralta CA, Adeney KL, Duprez DA, Jenny NS, Siscovick DS, Kestenbaum BR. Serum phosphorus concentrations and arterial stiffness among individuals with normal kidney function to moderate kidney disease in MESA. Clin J Am Soc Nephrol. 2009;4:609-615.
9. Palmer SC, Hayen A, Macaskill P, Pellegrini F, Craig JC, Elder GJ, Strippoli GF. Serum levels of phosphorus, parathyroid hormone, and calcium and risks of death and cardiovascular disease in individuals with chronic k idney disease: a systematic review and meta-analysis. JAMA. 2011;305:1119-1127.
10. Leifsson BG, Ahrén B. Serum calcium and survival in a large health screening program. J Clin Endocrinol Metab. 1996;81:2149-2153.
11. Dhingra R, Sullivan LM, Fox CS, Wang TJ, D'Agostino RB, Sr, Gaziano JM, Vasan RS. Relations of serum phosphorus and calcium levels to the incidence of cardiovascular disease in the community. Arch Intern Med. 2007;167:879-885.
12. Foley RN, Collins AJ, Ishani A, Kalra PA. Calcium-phosphate levels and cardiovascular disease in community-dwelling adults: the Atherosclerosis Risk in Communities (ARIC) Study. Am Heart J. 2008;156:556-563.
13. Budoff MJ, Achenbach S, Blumenthal RS, Carr JJ, Goldin JG, Greenland P, Guerci AD, Lima JA, Rader DJ, Rubin GD, Shaw LJ, Wiegers SE; American Heart Association Committee on Cardiovascular Imaging and Intervention; American Heart Association Council on Cardiovascular Radiology and Intervention; American Heart Association Committee on Cardiac Imaging, Council on Cli n ical Cardiology. Assessment of coronary artery disease by cardiac computed tomography: a scientific statement from the American Heart Association Committee on Cardiovascular Imaging and Intervention, Council on Cardiovascular Radiology and Intervention, a nd Committee on Cardiac Imaging, Council on Clinical Cardiology. Circulation. 2006;114:1761-1791.
14. Polonsky TS, McClelland RL, Jorgensen NW, Bild DE, Burke GL, Guerci AD, Greenland P. Coronary artery calcium score and risk classification for coronary heart disease prediction. JAMA. 2010;303:1610-1616.
15. Park KS, Chang JW, Kim TY, Kim HW, Lee EK, Kim HS, Yang WS, Kim SB, Park SK, Lee SK, Park JS. Lower concentrations of serum phosphorus within the normal range could be associated with les s calcification of the coronary artery in Koreans with normal renal function. Am J Clin Nutr. 2011;94:1465-1470.
16. Samelson EJ, Booth SL, Fox CS, Tucker KL, Wang TJ, Hoffmann U, Cupples LA, O' Donnell CJ, Kiel DP. Calcium intake is not associated with increased coronary artery calcification: the Framingham Study. Am J Clin Nutr. 2012;96:1274-1280.
17. Russo D, Palmiero G, De Blasio AP, Balletta MM, Andreucci VE. Coronary artery calcification in patients with CRF not undergoing dialysis. Am J Kidney Dis. 2004;44:1024-1030.
18. Srivaths PR, Goldstein SL, Silverstein DM, Krishnamurthy R, Brewer ED. Elevated FGF 23 and phosphorus are associated with coronary calcification in hemodialysis patients. Pediatr Nephrol. 2011;26:945-951.
19. Baber U, de Lemos JA, Khera A, McGuire DK, Omland T, Toto RD, Hedayat i SS. Non-traditional risk factors predict coronary calcification in chronic kidney disease in a population-based cohort. Kidney Int. 2008;73:615-621.
20. Foley RN. Phosphorus comes of age as a cardiovascular risk factor. Arch Intern Med. 2007;167:873-874.
21. Demer LL. A skeleton in the atherosclerosis closet. Circulation. 1995;92:2029-2032.
22. Alam MU, Kirton JP, Wilkinson FL, Tow ers E, Sinha S, Rouhi M, Vizard TN, Sage AP, Martin D, Ward DT, Alexander MY, Riccardi D, Canfield AE. Calcification is associated with loss of functional calcium-sensing receptor in vascular smooth muscle cells. Cardiovasc Res. 2009;81: 260-268.
23. Luo G, Ducy P, McKee MD, Pinero GJ, Loyer E, Behringer RR, Karsenty G. Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein. Nature. 1997;386:78-81.
24. Kapustin AN, Davies JD, Reynolds JL, McNair R, Jones GT, Sidibe A, Schurgers LJ, Skepper JN, Proudfoot D, Mayr M, Shanahan CM. Calcium regulates key components of vascular smooth muscle cell-derived matrix vesicles to enhance mineralization. Circ Res. 2011;109:e1-e12.
25. Yang H, Curinga G, Giachelli CM. Elevated extracellular calcium levels induce smooth muscle cell matrix mineralization in vitro. Kidney Int. 2004;66:2293-2299.
26. Reynolds JL, Joannides AJ, Skepper JN, McNair R, Schurgers LJ, Proudfoot D, Jahnen-Dechent W, Weissberg PL, Shanahan CM. Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated vascular calcification in ESRD. J Am Soc Nephrol. 2004;15:2857-2867.
27. Shroff R. Phosphate is a vascular toxin. Pediatr Nephrol. 2013;28:583-593.
28. Massy ZA, Drüeke TB. Vascular calcification. Curr Opin Nephrol Hypertens. 2013;22:405-412.
29. Watson KE, Abrolat ML, Malone LL, Hoeg JM, Doherty T, Detrano R, Demer LL. Active serum vitamin D levels are inversely correlated with coronary calcification. Circulation. 1997;96:1755-1760.
30. Grey A, Mitnick MA, Masiukiewicz U, Sun BH, Rudikoff S, Jilka RL, Manolagas SC, Insogna K. A role for interleukin-6 in parathyroid hormoneinduced bone resorption in vivo. Endocrinology. 1999;140:4683-4690.
31. Jenny NS, Brown ER, Detrano R, Folsom AR, Saad MF, Shea S, Szklo M, Herrington DM, Jacobs DR, Jr. Associations of inflammatory markers with coronary artery calcification: results from the Multi-Ethnic Study of Atherosclerosis. Atherosclerosis. 2010;209:226-229.
32. Murtaugh MA, Filipowicz R, Baird BC, Wei G, Greene T, Beddhu S. Dietary phosphorus intake and mortality in moderate chronic kidney disease: NHANES III. Nephrol Dial Transplant. 2012;27:990-996.
33. Li K, Kaaks R, Linseisen J, Rohrmann S. Association s of dietary calcium intake and calcium supplementation with myocardial infarction and stroke risk and overall cardiovascular mortality in the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition study (EPIC-Heidelberg). Heart. 2012;98:920-925.
34. de Boer IH, Rue TC, Kestenbaum B. Serum phosphorus concentrations in the third National Health and Nutrition Examination Survey (NHANES III). Am J Kidney Dis. 2009;53:399-407.
35. Wang L, Manson JE, Sesso HD. Calcium intake and risk of cardiovascular disease: a review of prospective studies and randomized clinical trials. Am J Cardiovasc Drugs. 2012;12:105-116.
36. Wexler L, Brundage B, Crouse J, Detrano R, Fuster V, Maddahi J, Rumberger J, Stanford W, White R, Taubert K. Coronary artery calcification: pathophysiology, epidemiology, imaging method s, and clinical implications. A statement for health professionals from the American Heart Association. Writing Group. Circulation. 1996;94:1175-1192.
37. The Korean Nutrition Society. Dietary Reference Intakes for Koreans, 1st Revision. Seoul: The Korean Nutrition Society; 2010.
38. US Institute of Medicine. Dietary Reference Intakes for Calcium and Vitamin D. Washington, DC: The National Academies Press; 2011.
39. Michaëlsson K, Melhus H, Warensjö Lemming E, Wolk A, Byberg L. Long term calcium intake and rates of all cause and cardiovascular mortality: community based prospective longitudinal cohort study. BMJ. 2013;346:f228.
40. Bostick RM, Kushi LH, Wu Y, Meyer KA, Sellers TA, Folsom AR. Relation of calcium, vitamin D, and dairy food intake to ischemic heart disease mortality among postmenopausal women. Am J Epidemiol. 1999;149:151-161.