Zebrafish and mouse TASK-2 K+ channels are inhibited by increased CO2 and intracellular acidification

Pflugers Archiv European Journal of Physiology

Volumn 466, Issue 7, 2014, Pages 1317-1327

  Peña Münzenmayer, Gaspar ^a,b   Niemeyer, María Isabel ^a   Sepúlveda, Francisco V ^a   Cid, L Pablo ^a  

^a CENTRO DE ESTUDIOS CIENTÍFICOS CECS   (Chile)

^b NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

Intracellular pH; Mouse TASK 2; Zebrafish TASK 2

Indexed keywords

CARBON DIOXIDE; CARBONATE DEHYDRATASE; GUANINE NUCLEOTIDE BINDING PROTEIN; POTASSIUM CHANNEL; POTASSIUM CHANNEL TASK 2; UNCLASSIFIED DRUG; CARBONATE DEHYDRATASE INHIBITOR; KCNK5 PROTEIN, MOUSE; TANDEM PORE DOMAIN POTASSIUM CHANNEL; TASK-2 PROTEIN, ZEBRAFISH; ZEBRAFISH PROTEIN;

ACIDIFICATION; ALKALINIZATION; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BLOOD PH; CARBOXY TERMINAL SEQUENCE; CELL PH; CHEMORECEPTOR; CONTROLLED STUDY; ENZYME INHIBITION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POTASSIUM CURRENT; PRIORITY JOURNAL; REGULATORY MECHANISM; SEQUENCE ALIGNMENT; ZEBRA FISH; ACTION POTENTIAL; ANIMAL; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; GENETICS; GILL; HEK293 CELL LINE; HUMAN; METABOLISM; MOLECULAR GENETICS; MUTATION; NERVE CELL; PH; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

ACTION POTENTIALS; AMINO ACID SEQUENCE; ANIMALS; CARBON DIOXIDE; CARBONIC ANHYDRASE INHIBITORS; GILLS; HEK293 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; MICE; MOLECULAR SEQUENCE DATA; MUTATION; NEURONS; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; PROTEIN STRUCTURE, TERTIARY; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84904682190     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-013-1365-2     Document Type: Article

References (50)

1. 2+ and pH. Adv Exp Med Biol 758:143-148
2. Al-Samir S, Papadopoulos S, Scheibe RJ, Meissner JD, Cartron JP, Sly WS, Alper SL, Gros G, Endeward V (2013) Activity and distribution of intracellular carbonic anhydrase II and their effects on the transport activity of anion exchanger AE1/SLC4A1. J Physiol. doi:10.1113/jphysiol.2013.251181
3. 2P potassium channel TASK-2: a role of basic residues in the C-terminus domain. Pflugers Arch. doi:10.1007/s00424-013-1314-0
4. Baxter KA, Church J (1996) Characterization of acid extrusion mechanisms in cultured fetal rat hippocampal neurones. J Physiol 493:457-470 (Pubitemid 26187505)
5. --related species. Biochim Biophys Acta 1804:410-421
6. -. Am J Physiol 255:C844-C856
7. Chávez RA, Gray AT, Zhao BB, Kindler CH, Mazurek MJ, Mehta Y, Forsayeth JR, Yost CS (1999) TWIK-2, a new weak inward rectifying member of the tandem pore domain potassium channel family. J Biol Chem 274:7887-7892
8. Cid LP, Niemeyer MI, Ramírez A, Sepúlveda FV (2000) Splice variants of a ClC-2 chloride channel with differing functional characteristics. Am J Physiol 279:C1198-C1210
9. + channel with complex regulation and diverse physiological functions. Frontiers in Physiology 4:doi: 10.3389/fphys.2013.00198
10. Claiborne JB, Heisler N (1986) Acid-base regulation and ion transfers in the carp (Cyprinus carpio) : pH compensation during graded long- and short-term environmental hypercapnia, and the effect of bicarbonate infusion. J Exp Biol 126:41-61
11. 2? Int J Biochem Cell Biol 39:1204-1210
12. 2-formatics: how do proteins bind carbon dioxide? J Chem Inf Model 49:2111-2115
13. 2/pH sensitivity. J Biol Chem 286:192-198
14. + currents: two-pore domain potassiumchannels. Physiol Rev 90:559-605
15. Filosa JA, Dean JB, Putnam RW (2002) Role of intracellular and extracellular pH in the chemosensitive response of rat locus coeruleus neurones. J Physiol 541:493-509 (Pubitemid 35190215)
16. 2 during eupneic breathing. Adv Exp Med Biol 605:322-326
17. 2 sensitivity. Proc Natl Acad Sci U S A 107:2325-2330
18. + channels. Biochim Biophys Acta 1818:33-41
19. Hibino H, Inanobe A, Furutani K, Murakami S, Findlay I, Kurachi Y (2010) Inwardly rectifying potassium channels: their structure, function, and physiological roles. Physiol Rev 90:291-366
20. + channel. Pflugers Arch 461:337-344
21. Ishimatsu A, Iwama GK, Bentley DB, Heisler N (1992) Contribution of the secondary circulatory system to acid-base regulation during hypercapnia in rainbow trout (Onchrryncus mykiss) . J Exp Biol 170:43-56
22. + uptake. Front Physiol 4:59
23. 2 central chemosensitivity: why are there so many sensing molecules? Respir Physiol Neurobiol 145:115-126
24. Jonz MG, Fearon IM, Nurse CA (2004) Neuroepithelial oxygen chemoreceptors of the zebrafish gill. J Ph 560:737-752 (Pubitemid 39530114)
25. + channels by pressure, free fatty acids and alkali. Pflugers Arch 442:64-72
26. + channel with a novel structure. Embo J 15:1004-1011
27. + channel with multiple regulations by polyunsaturated fatty acids, lysophospholipids, and Gs, Gi, and Gq protein-coupled receptors. J Biol Chem 275:28398-28405
28. López-Barneo J, Ortega-Sáenz P, Pardal R, Pascual A, Piruat JI (2008) Carotid body oxygen sensing. Eur Respir J 32:1386-1398
29. Maingret F, Patel AJ, Lesage F, Lazdunski M, Honore E (1999) Mechano- or acid stimulation, two interactive modes of activation of the TREK-1 potassium channel. J Biol Chem 274:26691-26696
30. Mölich A, Heisler N (2005) Determination of pH by microfluorometry: intracellular and interstitial pH regulation in developing early-stage fish embryos (Danio rerio). J Exp Biol 208:4137-4149 (Pubitemid 41728317)
31. Mulkey DK, Stornetta RL, Weston MC, Simmons JR, Parker A, Bayliss DA, Guyenet PG (2004) Respiratory control by ventral surface chemoreceptor neurons in rats. Nat Neurosci 7:1360-1369 (Pubitemid 41057759)
32. Mulkey DK, Talley EM, Stornetta RL, Siegel AR, West GH, Chen X, Sen N, Mistry AM, Guyenet PG, Bayliss DA (2007) TASK channels determine pH sensitivity in select respiratory neurons but do not contribute to central respiratory chemosensitivity. J Neurosci 27:14049-14058 (Pubitemid 351377868)
33. Nattie E, Li A (2009) Central chemoreception is a complex system function that involves multiple brain stem sites. J Appl Physiol 106:1464-1466
34. + channel TASK-2 (KCNK5) by changes in cell volume. J Biol Chem 276:43166-43174
35. 2P potassium channel TASK-2 by intra- and extracellular pH. J Biol Chem 285:16467-16475
36. Niemeyer MI, González-Nilo FD, Zúñiga L, González W, Cid LP, Sepúlveda FV (2007)Neutralization of a single arginine residue gates open a two-pore domain, alkali-activated K+ channel. Proc Natl Acad Sci U S A 104:666-671 (Pubitemid 46123082)
37. Ortega-Sáenz P, Levitsky KL, Marcos-Almaraz MT, Bonilla-Henao V, Pascual A, López-Barneo J (2010) Carotid body chemosensory responses in mice deficient of TASK channels. J Gen Physiol 135:379-392
38. Perry SF, Abdallah S (2012) Mechanisms and consequences of carbon dioxide sensing in fish. Respir Physiol Neurobiol 184:309-315
39. 2 and acid signaling in chemosensitive neurons. Am J Physiol 287:C1493-C1526
40. 2. J Physiol 588:861-872
41. + channel from human kidney. J Biol Chem 273:30863-30869
42. Roos A, Boron WF (1981) Intracellular pH. Physiol Rev 61:296-434
43. Trapp S, Aller MI, Wisden W, Gourine AV (2008) A role for TASK-1 (KCNK3) channels in the chemosensory control of breathing. J Neurosci 28:8844-8850
44. Trapp S, Tucker SJ, Gourine AV (2011) Respiratory responses to hypercapnia and hypoxia in mice with genetic ablation of Kir5.1 (Kcnj16) . Exp Physiol 96:451-459
45. - exchanger. J Biol Chem 273:28430-28437
46. Wang W, Pizzonia JH, Richerson GB (1998) Chemosensitivity of rat medullary raphe neurones in primary tissue culture. J Physiol 511:433-450 (Pubitemid 28444613)
47. + channel-deficient mice reveals a mechanism for stabilizing bicarbonate transport. Proc Natl Acad Sci U S A 101:8215-8220
48. 2-sensitive Kir channels in brainstem neurons of rats. J Membr Biol 197:179-191
49. Xu H, Cui N, Yang Z, Qu Z, Jiang C (2000) Modulation of Kir4.1 and Kir5.1 by hypercapnia and intracellular acidosis. J Physiol 524:725-735 (Pubitemid 30303621)
50. + channels in retinal pigment epithelial cells by intracellular pH. J Physiol 549:429-438