Genetic inactivation of Kcnj16 identifies Kir5.1 as an important determinant of neuronal PCO2/pH sensitivity

Journal of Biological Chemistry

Volumn 286, Issue 1, 2011, Pages 192-198

  D'Adamo, M Cristina ^a   Shang, Lijun ^b   Imbrici, Paola ^a   Brown, Steve D M ^b,c   Pessia, Mauro ^a   Tucker, Stephen J ^b  

^a UNIVERSITY OF PERUGIA   (Italy)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c MRC MAMMALIAN GENETICS UNIT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRAINSTEM; CHEMOSENSITIVITY; CYTOPLASMIC ALKALINIZATION; DELAYED RESPONSE; HIGHLY SENSITIVE; INTRACELLULAR PH; ION CHANNEL; MOLECULAR IDENTITIES; MUTANT MICE; PH SENSITIVITY;

NEURONS;

PH SENSORS;

INWARDLY RECTIFYING POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR5.1; UNCLASSIFIED DRUG;

ACIDIFICATION; ACIDOSIS; ALKALINIZATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CARBON DIOXIDE TENSION; CONTROLLED STUDY; CYTOPLASM; EMBRYO; GENE INACTIVATION; HYPERCAPNIA; LOCUS CERULEUS; MALE; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL;

ACIDOSIS; ANIMALS; CARBON DIOXIDE; ELECTRIC CONDUCTIVITY; FEMALE; GENE DELETION; HYDROGEN-ION CONCENTRATION; LOCUS COERULEUS; MALE; MICE; MICE, INBRED C57BL; NEURONS; POTASSIUM CHANNELS, INWARDLY RECTIFYING;

MUS;

EID: 78650952629     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.189290     Document Type: Article

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