Metabolites identification of glycycoumarin, a major bioactive coumarin from licorice in rats

Journal of Pharmaceutical and Biomedical Analysis

Volumn 98, Issue , 2014, Pages 287-295

  Wang, Qi ^a   Qiao, Xue ^a   Liu, Chun fang ^a   Ji, Shuai ^a   Feng, Lin min ^a   Qian, Yi ^a   Guo, De an ^a   Ye, Min ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Glycycoumarin; Glycyrrhiza uralensis; LC MS; Metabolites identification; NMR

Indexed keywords

4'' HYDROXYL GLYCYCOUMARIN; 5'' HYDROXYL GLYCYCOUMARIN; ANTIINFECTIVE AGENT; BETA GLUCURONIDASE; COUMARIN DERIVATIVE; CYTOCHROME P450; DRUG METABOLITE; GLUCURONIDE; GLYCYCOUMARIN; UNCLASSIFIED DRUG; COUMARIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG GLUCURONIDATION; DRUG HYDROLYSIS; DRUG HYDROXYLATION; DRUG IDENTIFICATION; DRUG METABOLISM; DRUG STRUCTURE; DRUG URINE LEVEL; GLYCYRRHIZA URALENSIS; HYDROGENATION; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; RAT; SYNCEPHALASTRUM RACEMOSUM; TANDEM MASS SPECTROMETRY; ANIMAL; CHEMISTRY; GLYCYRRHIZA; HYDROXYLATION; LIVER MICROSOME; MASS SPECTROMETRY; METABOLISM; PROCEDURES; SPRAGUE DAWLEY RAT;

ANIMALS; CHROMATOGRAPHY, LIQUID; COUMARINS; GLUCURONIDASE; GLUCURONIDES; GLYCYRRHIZA; GLYCYRRHIZA URALENSIS; HYDROXYLATION; MALE; MASS SPECTROMETRY; MICROSOMES, LIVER; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84904654589     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2014.06.001     Document Type: Article

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