메뉴 건너뛰기




Volumn 2014, Issue , 2014, Pages

Implications of heterogeneity in multiple myeloma

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BRCA2 PROTEIN; BREAST CANCER RESISTANCE PROTEIN; CYCLIN D1; CYCLIN D3; HISTONE ACETYLTRANSFERASE; HISTONE DEMETHYLASE; IMMUNOGLOBULIN HEAVY CHAIN; K RAS PROTEIN; OSTEOGENIN; POLYCOMB REPRESSIVE COMPLEX 2; PROTEIN P53; TRANSCRIPTION FACTOR RUNX2; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3;

EID: 84904635505     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2014/232546     Document Type: Review
Times cited : (45)

References (89)
  • 1
    • 42449114035 scopus 로고    scopus 로고
    • Multiple myeloma
    • 2-s2.0-42449114035 10.1182/blood-2007-10-078022
    • Kyle R. A., Rajkumar S. V., Multiple myeloma. Blood 2008 111 6 2962 2972 2-s2.0-42449114035 10.1182/blood-2007-10-078022
    • (2008) Blood , vol.111 , Issue.6 , pp. 2962-2972
    • Kyle, R.A.1    Rajkumar, S.V.2
  • 2
    • 67049114114 scopus 로고    scopus 로고
    • A monoclonal gammopathy precedes multiple myeloma in most patients
    • 2-s2.0-67049114114 10.1182/blood-2008-12-195008
    • Weiss B. M., Abadie J., Verma P., Howard R. S., Kuehl W. M., A monoclonal gammopathy precedes multiple myeloma in most patients. Blood 2009 113 22 5418 5422 2-s2.0-67049114114 10.1182/blood-2008-12-195008
    • (2009) Blood , vol.113 , Issue.22 , pp. 5418-5422
    • Weiss, B.M.1    Abadie, J.2    Verma, P.3    Howard, R.S.4    Kuehl, W.M.5
  • 4
    • 84860219443 scopus 로고    scopus 로고
    • The genetic architecture of multiple myeloma
    • 2-s2.0-84860219443 10.1038/nrc3257
    • Morgan G. J., Walker B. A., Davies F. E., The genetic architecture of multiple myeloma. Nature Reviews Cancer 2012 12 5 335 348 2-s2.0-84860219443 10.1038/nrc3257
    • (2012) Nature Reviews Cancer , vol.12 , Issue.5 , pp. 335-348
    • Morgan, G.J.1    Walker, B.A.2    Davies, F.E.3
  • 5
    • 84895784261 scopus 로고    scopus 로고
    • New drugs and novel mechanisms of action in multiple myeloma in 2013: A report from the International Myeloma Working Group (IMWG)
    • Ocio E. M., Richardson P. G., Rajkumar S. V., New drugs and novel mechanisms of action in multiple myeloma in 2013: a report from the International Myeloma Working Group (IMWG). Leukemia 2014 28 525 542
    • (2014) Leukemia , vol.28 , pp. 525-542
    • Ocio, E.M.1    Richardson, P.G.2    Rajkumar, S.V.3
  • 9
    • 58149195202 scopus 로고    scopus 로고
    • Neurobeachin (NBEA) is a target of recurrent interstitial deletions at 13q13 in patients with MGUS and multiple myeloma
    • 2-s2.0-58149195202 10.1016/j.exphem.2008.10.014
    • O'Neal J., Gao F., Hassan A., Monahan R., Barrios S., Lee I., Chng W. J., Vij R., Tomasson M. H., Neurobeachin (NBEA) is a target of recurrent interstitial deletions at 13q13 in patients with MGUS and multiple myeloma. Experimental Hematology 2009 37 2 234 244 2-s2.0-58149195202 10.1016/j.exphem.2008.10.014
    • (2009) Experimental Hematology , vol.37 , Issue.2 , pp. 234-244
    • O'Neal, J.1    Gao, F.2    Hassan, A.3    Monahan, R.4    Barrios, S.5    Lee, I.6    Chng, W.J.7    Vij, R.8    Tomasson, M.H.9
  • 11
    • 27144453882 scopus 로고    scopus 로고
    • Elevated expression of CKS1B at 1q21 is highly correlated with short survival in myeloma
    • 10477
    • Zhan F., Sawyer J., Gupta S., Elevated expression of CKS1B at 1q21 is highly correlated with short survival in myeloma. Blood 2004 104, abstract 77
    • (2004) Blood
    • Zhan, F.1    Sawyer, J.2    Gupta, S.3
  • 13
    • 0027957089 scopus 로고
    • Human and mouse chromosomal mapping of the myeloid cell leukemia-1 gene: MCL1 maps to human chromosome 1q21, a region that is frequently altered in preneoplastic and neoplastic disease
    • DOI 10.1006/geno.1994.1523
    • Craig R. W., Jabs E. W., Zhou P., Kozopas K. M., Hawkins A. L., Rochelle J. M., Seldin M. F., Griffin C. A., Human and mouse chromosomal mapping of the myeloid cell leukemia-1 gene: MCL1 maps to human chromosome 1q21, a region that is frequently altered in preneoplastic and neoplastic disease. Genomics 1994 23 2 457 463 2-s2.0-0027957089 10.1006/geno.1994.1523 (Pubitemid 24308268)
    • (1994) Genomics , vol.23 , Issue.2 , pp. 457-463
    • Craig, R.W.1    Jabs, E.W.2    Zhou, P.3    Kozopas, K.M.4    Hawkins, A.L.5    Rochelle, J.M.6    Seldin, M.F.7    Griffin, C.A.8
  • 14
    • 3042683879 scopus 로고    scopus 로고
    • Overexpression of PDZK1 within the 1q12-q22 amplicon is likely to be associated with drug-resistance phenotype in multiple myeloma
    • Inoue J., Otsuki T., Hirasawa A., Imoto I., Matsuo Y., Shimizu S., Taniwaki M., Inazawa J., Overexpression of PDZK1 within the 1q12-q22 amplicon is likely to be associated with drug-resistance phenotype in multiple myeloma. American Journal of Pathology 2004 165 1 71 81 2-s2.0-3042683879 (Pubitemid 38821815)
    • (2004) American Journal of Pathology , vol.165 , Issue.1 , pp. 71-81
    • Inoue, J.1    Otsuki, T.2    Hirasawa, A.3    Imoto, I.4    Matsuo, Y.5    Shimizu, S.6    Taniwaki, M.7    Inazawa, J.8
  • 15
    • 0034655650 scopus 로고    scopus 로고
    • MUC1 is activated in a B-cell lymphoma by the t(1;14)(q21;q32) translocation and is rearranged and amplified in B-cell lymphoma subsets
    • Dyomin V. G., Palanisamy N., Lloyd K. O., Dyomina K., Jhanwar S. C., Houldsworth J., Chaganti R. S. K., MUC1 is activated in a B-cell lymphoma by the t(1;14)(q21;q32) translocation and is rearranged and amplified in B-cell lymphoma subsets. Blood 2000 95 8 2666 2671 2-s2.0-0034655650 (Pubitemid 30210548)
    • (2000) Blood , vol.95 , Issue.8 , pp. 2666-2671
    • Dyomin, V.G.1    Palanisamy, N.2    Lloyd, K.O.3    Dyomina, K.4    Jhanwar, S.C.5    Houldsworth, J.6    Chaganti, R.S.K.7
  • 16
    • 77950949924 scopus 로고    scopus 로고
    • Correlation between array-comparative genomic hybridization-defined genomic gains and losses and survival: Identification of 1p31-32 deletion as a prognostic factor in myeloma
    • 2-s2.0-77950949924 10.1038/leu.2010.21
    • Chng W. J., Gertz M. A., Chung T.-H., Van Wier S., Keats J. J., Baker A., Bergsagel P. L., Carpten J., Fonseca R., Correlation between array-comparative genomic hybridization-defined genomic gains and losses and survival: identification of 1p31-32 deletion as a prognostic factor in myeloma. Leukemia 2010 24 4 833 842 2-s2.0-77950949924 10.1038/leu.2010.21
    • (2010) Leukemia , vol.24 , Issue.4 , pp. 833-842
    • Chng, W.J.1    Gertz, M.A.2    Chung, T.-H.3    Van Wier, S.4    Keats, J.J.5    Baker, A.6    Bergsagel, P.L.7    Carpten, J.8    Fonseca, R.9
  • 19
    • 0035892119 scopus 로고    scopus 로고
    • Rearrangements of the c-myc oncogene are present in 15% of primary human multiple myeloma tumors
    • 2-s2.0-0035892119 10.1182/blood.V98.10.3082
    • Avet-Loiseau H., Gerson F., Magrangeas F., Minvielle S., Harousseau J.-L., Bataille R., Rearrangements of the c-myc oncogene are present in 15% of primary human multiple myeloma tumors. Blood 2001 98 10 3082 3086 2-s2.0-0035892119 10.1182/blood.V98.10.3082
    • (2001) Blood , vol.98 , Issue.10 , pp. 3082-3086
    • Avet-Loiseau, H.1    Gerson, F.2    Magrangeas, F.3    Minvielle, S.4    Harousseau, J.-L.5    Bataille, R.6
  • 20
    • 79958095463 scopus 로고    scopus 로고
    • Clinical and biological implications of MYC activation: A common difference between MGUS and newly diagnosed multiple myeloma
    • 2-s2.0-79958095463 10.1038/leu.2011.53
    • Chng W.-J., Huang G. F., Chung T. H., Ng S. B., Gonzalez-Paz N., Troska-Price T., Mulligan G., Chesi M., Bergsagel P. L., Fonseca R., Clinical and biological implications of MYC activation: a common difference between MGUS and newly diagnosed multiple myeloma. Leukemia 2011 25 6 1026 1035 2-s2.0-79958095463 10.1038/leu.2011.53
    • (2011) Leukemia , vol.25 , Issue.6 , pp. 1026-1035
    • Chng, W.-J.1    Huang, G.F.2    Chung, T.H.3    Ng, S.B.4    Gonzalez-Paz, N.5    Troska-Price, T.6    Mulligan, G.7    Chesi, M.8    Bergsagel, P.L.9    Fonseca, R.10
  • 21
    • 84904683918 scopus 로고    scopus 로고
    • Promiscuous rearrangements of the MYC locus hijack enhancers and super-enhancers to dysregulate MYC expression in multiple myeloma
    • Affer M., Chesi M., Chen W. D., Promiscuous rearrangements of the MYC locus hijack enhancers and super-enhancers to dysregulate MYC expression in multiple myeloma. Leukemia 2014
    • (2014) Leukemia
    • Affer, M.1    Chesi, M.2    Chen, W.D.3
  • 23
    • 36749027626 scopus 로고    scopus 로고
    • Genetic events in the pathogenesis of multiple myeloma
    • DOI 10.1016/j.beha.2007.08.004, PII S1521692607000643, New Insights into the Biology and Advances in the Management of Multiple Myeloma
    • Chng W. J., Glebov O., Bergsagel P. L., Kuehl W. M., Genetic events in the pathogenesis of multiple myeloma. Best Practice and Research: Clinical Haematology 2007 20 4 571 596 2-s2.0-36749027626 10.1016/j.beha.2007.08.004 (Pubitemid 350215376)
    • (2007) Best Practice and Research in Clinical Haematology , vol.20 , Issue.4 , pp. 571-596
    • Chng, W.J.1    Glebov, O.2    Bergsagel, P.L.3    Kuehl, W.M.4
  • 24
    • 84892409192 scopus 로고    scopus 로고
    • Widespread genetic heterogeneity in multiple myeloma: Implications for targeted therapy
    • Lohr J. G., Stojanov P., Carter S. L., Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy. Cancer Cell 2014 25 91 101
    • (2014) Cancer Cell , vol.25 , pp. 91-101
    • Lohr, J.G.1    Stojanov, P.2    Carter, S.L.3
  • 25
    • 11144235574 scopus 로고    scopus 로고
    • Possible roles for activating RAS mutations in the MGUS to MM transition and in the intramedullary to extramedullary transition in some plasma cell tumors
    • DOI 10.1182/blood-2004-03-0833
    • Rasmussen T., Kuehl M., Lodahl M., Johnsen H. E., Dahl I. M. S., Possible roles for activating RAS mutations in the MGUS to MM transition and in the intramedullary to extramedullary transition in some plasma cell tumors. Blood 2005 105 1 317 323 2-s2.0-11144235574 10.1182/blood-2004-03-0833 (Pubitemid 40053099)
    • (2005) Blood , vol.105 , Issue.1 , pp. 317-323
    • Rasmussen, T.1    Kuehl, M.2    Lodahl, M.3    Johnsen, H.E.4    Dahl, I.M.S.5
  • 27
    • 22044440425 scopus 로고    scopus 로고
    • Cyclin D dysregulation: An early and unifying pathogenic event in multiple myeloma
    • DOI 10.1182/blood-2005-01-0034
    • Bergsagel P. L., Kuehl W. M., Zhan F., Sawyer J., Barlogie B., Shaughnessy J. Jr., Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma. Blood 2005 106 1 296 303 2-s2.0-22044440425 10.1182/blood-2005-01-0034 (Pubitemid 40967205)
    • (2005) Blood , vol.106 , Issue.1 , pp. 296-303
    • Bergsagel, P.L.1    Kuehl, W.M.2    Zhan, F.3    Sawyer, J.4    Barlogie, B.5    Shaughnessy Jr., J.6
  • 33
    • 36849014859 scopus 로고    scopus 로고
    • Role of genetics in prognostication in myeloma
    • DOI 10.1016/j.beha.2007.08.005, PII S1521692607000667, New Insights into the Biology and Advances in the Management of Multiple Myeloma
    • Avet-Loiseau H., Role of genetics in prognostication in myeloma. Best Practice and Research: Clinical Haematology 2007 20 4 625 635 2-s2.0-36849014859 10.1016/j.beha.2007.08.005 (Pubitemid 350225352)
    • (2007) Best Practice and Research in Clinical Haematology , vol.20 , Issue.4 , pp. 625-635
    • Avet-Loiseau, H.1
  • 34
    • 33748196399 scopus 로고    scopus 로고
    • Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: Incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation
    • DOI 10.1182/blood-2006-03-009910
    • Hanamura I., Stewart J. P., Huang Y., Zhan F., Santra M., Sawyer J. R., Hollmig K., Zangarri M., Pineda-Roman M., Van Rhee F., Cavallo F., Burington B., Crowley J., Tricot G., Barlogie B., Shaughnessy J. D. Jr., Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation. Blood 2006 108 5 1724 1732 2-s2.0-33748196399 10.1182/blood-2006-03-009910 (Pubitemid 44316143)
    • (2006) Blood , vol.108 , Issue.5 , pp. 1724-1732
    • Hanamura, I.1    Stewart, J.P.2    Huang, Y.3    Zhan, F.4    Santra, M.5    Sawyer, J.R.6    Hollmig, K.7    Zangarri, M.8    Pineda-Roman, M.9    Van Rhee, F.10    Cavallo, F.11    Burington, B.12    Crowley, J.13    Tricot, G.14    Barlogie, B.15    Shaughnessy Jr., J.D.16
  • 43
    • 84894041669 scopus 로고    scopus 로고
    • Mutation of NRAS but not KRAS significantly reduces myeloma sensitivity to single-agent bortezomib therapy
    • Mulligan G., Lichter D. I., di Bacco A., Mutation of NRAS but not KRAS significantly reduces myeloma sensitivity to single-agent bortezomib therapy. Blood 2014 123 632 639
    • (2014) Blood , vol.123 , pp. 632-639
    • Mulligan, G.1    Lichter, D.I.2    Di Bacco, A.3
  • 46
    • 0016804136 scopus 로고
    • A clinical staging system for multiple myeloma. Correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival
    • 2-s2.0-0016804136
    • Durie B. G. M., Salmon S. E., A clinical staging system for multiple myeloma. Correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival. Cancer 1975 36 3 842 854 2-s2.0-0016804136
    • (1975) Cancer , vol.36 , Issue.3 , pp. 842-854
    • Durie, B.G.M.1    Salmon, S.E.2
  • 49
    • 29844450880 scopus 로고    scopus 로고
    • Using genomics to identify high-risk myeloma after autologous stem cell transplantation
    • DOI 10.1016/j.bbmt.2005.10.002, PII S1083879105006786
    • Shaughnessy J. D. Jr., Barlogie B., Using genomics to identify high-risk myeloma after autologous stem cell transplantation. Biology of Blood and Marrow Transplantation 2006 12 1 77 80 2-s2.0-29844450880 10.1016/j.bbmt.2005.10.002 (Pubitemid 43034124)
    • (2006) Biology of Blood and Marrow Transplantation , vol.12 , Issue.SUPPL. 1 , pp. 77-80
    • Shaughnessy Jr., J.D.1    Barlogie, B.2
  • 50
    • 54249092519 scopus 로고    scopus 로고
    • Prediction of survival in multiple myeloma based on gene expression profiles reveals cell cycle and chromosomal instability signatures in high-risk patients and hyperdiploid signatures in low-risk patients: A study of the Intergroupe Francophone du Myélome
    • 2-s2.0-54249092519 10.1200/JCO.2007.13.8545
    • Decaux O., Lodé L., Magrangeas F., Charbonnel C., Gouraud W., Jézéquel P., Attal M., Harousseau J.-L., Moreau P., Bataille R., Campion L., Avet-Loiseau H., Minvielle S., Prediction of survival in multiple myeloma based on gene expression profiles reveals cell cycle and chromosomal instability signatures in high-risk patients and hyperdiploid signatures in low-risk patients: a study of the Intergroupe Francophone du Myélome. Journal of Clinical Oncology 2008 26 29 4798 4805 2-s2.0-54249092519 10.1200/JCO.2007.13.8545
    • (2008) Journal of Clinical Oncology , vol.26 , Issue.29 , pp. 4798-4805
    • Decaux, O.1    Lodé, L.2    Magrangeas, F.3    Charbonnel, C.4    Gouraud, W.5    Jézéquel, P.6    Attal, M.7    Harousseau, J.-L.8    Moreau, P.9    Bataille, R.10    Campion, L.11    Avet-Loiseau, H.12    Minvielle, S.13
  • 51
    • 38949203768 scopus 로고    scopus 로고
    • The centrosome index is a powerful prognostic marker in myeloma and identifies a cohort of patients that might benefit from aurora kinase inhibition
    • DOI 10.1182/blood-2007-06-097774
    • Chng W. J., Braggio E., Mulligan G., Bryant B., Remstein E., Valdez R., Dogan A., Fonseca R., The centrosome index is a powerful prognostic marker in myeloma and identifies a cohort of patients that might benefit from aurora kinase inhibition. Blood 2008 111 3 1603 1609 2-s2.0-38949203768 10.1182/blood-2007-06-097774 (Pubitemid 351213451)
    • (2008) Blood , vol.111 , Issue.3 , pp. 1603-1609
    • Chng, W.J.1    Braggio, E.2    Mulligan, G.3    Bryant, B.4    Remstein, E.5    Valdez, R.6    Dogan, A.7    Fonseca, R.8
  • 53
    • 79953892192 scopus 로고    scopus 로고
    • A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines
    • 2-s2.0-79953892192 10.3324/haematol.2010.033456
    • Moreaux J., Klein B., Bataille R., Descamps G., Maïga S., Hose D., Goldschmidt H., Jauch A., Rème T., Jourdan M., Amiot M., Pellat-Deceunynck C., A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines. Haematologica 2011 96 4 574 582 2-s2.0-79953892192 10.3324/haematol.2010.033456
    • (2011) Haematologica , vol.96 , Issue.4 , pp. 574-582
    • Moreaux, J.1    Klein, B.2    Bataille, R.3    Descamps, G.4    Maïga, S.5    Hose, D.6    Goldschmidt, H.7    Jauch, A.8    Rème, T.9    Jourdan, M.10    Amiot, M.11    Pellat-Deceunynck, C.12
  • 56
    • 84879266916 scopus 로고    scopus 로고
    • A novel measure of chromosome instability can account for prognostic difference in multiple myeloma
    • 2-s2.0-84879266916 10.1371/journal.pone.0066361 e66361
    • Chung T.-H., Mulligan G., Fonseca R., Chng W. J., A novel measure of chromosome instability can account for prognostic difference in multiple myeloma. PLoS ONE 2013 8 6 2-s2.0-84879266916 10.1371/journal.pone.0066361 e66361
    • (2013) PLoS ONE , vol.8 , Issue.6
    • Chung, T.-H.1    Mulligan, G.2    Fonseca, R.3    Chng, W.J.4
  • 57
    • 84893782640 scopus 로고    scopus 로고
    • IMWG consensus on risk stratification in multiple myeloma
    • Chng W. J., Dispenzieri A., Chim C. S., IMWG consensus on risk stratification in multiple myeloma. Leukemia 2014 28 269 277
    • (2014) Leukemia , vol.28 , pp. 269-277
    • Chng, W.J.1    Dispenzieri, A.2    Chim, C.S.3
  • 58
    • 84867744264 scopus 로고    scopus 로고
    • Evolution of the cancer genome
    • 2-s2.0-84867744264 10.1038/nrg3317
    • Yates L. R., Campbell P. J., Evolution of the cancer genome. Nature Reviews Genetics 2012 13 11 795 806 2-s2.0-84867744264 10.1038/nrg3317
    • (2012) Nature Reviews Genetics , vol.13 , Issue.11 , pp. 795-806
    • Yates, L.R.1    Campbell, P.J.2
  • 59
    • 84892699941 scopus 로고    scopus 로고
    • Heterogeneity of genomic evolution and mutational profiles in multiple myeloma
    • 52997
    • Bolli N., Avet-Loiseau H., Wedge D. C., Heterogeneity of genomic evolution and mutational profiles in multiple myeloma. Nature Communications 2014 5, article 2997
    • (2014) Nature Communications
    • Bolli, N.1    Avet-Loiseau, H.2    Wedge, D.C.3
  • 62
    • 79952120598 scopus 로고    scopus 로고
    • Cancer: When catastrophe strikes a cell
    • 2-s2.0-79952120598 10.1038/470476a
    • Tubio J. M. C., Estivill X., Cancer: when catastrophe strikes a cell. Nature 2011 470 7335 476 477 2-s2.0-79952120598 10.1038/470476a
    • (2011) Nature , vol.470 , Issue.7335 , pp. 476-477
    • Tubio, J.M.C.1    Estivill, X.2
  • 63
    • 79960693423 scopus 로고    scopus 로고
    • Chromothripsis identifies a rare and aggressive entity among newly diagnosed multiple myeloma patients
    • 2-s2.0-79960693423 10.1182/blood-2011-03-344069
    • Magrangeas F., Avet-Loiseau H., Munshi N. C., Minvielle S., Chromothripsis identifies a rare and aggressive entity among newly diagnosed multiple myeloma patients. Blood 2011 118 3 675 678 2-s2.0-79960693423 10.1182/blood-2011-03-344069
    • (2011) Blood , vol.118 , Issue.3 , pp. 675-678
    • Magrangeas, F.1    Avet-Loiseau, H.2    Munshi, N.C.3    Minvielle, S.4
  • 66
    • 0019378791 scopus 로고
    • The growth fraction of human myeloma cells
    • Drewinko B., Alexanian R., Boyer H., Barlogie B., Rubinow S. I., The growth fraction of human myeloma cells. Blood 1981 57 2 333 338 2-s2.0-0019378791 (Pubitemid 11174896)
    • (1981) Blood , vol.57 , Issue.2 , pp. 333-338
    • Drewinko, B.1    Alexanian, R.2    Boyer, H.3
  • 67
    • 0017718628 scopus 로고
    • Primary bioassay of human myeloma stem cells
    • Hamburger A., Salmon S. S., Primary bioassay of human myeloma stem cells. Journal of Clinical Investigation 1977 60 4 846 854 2-s2.0-0017718628 (Pubitemid 8208477)
    • (1977) Journal of Clinical Investigation , vol.60 , Issue.4 , pp. 846-854
    • Hamburger, A.1    Salmon, S.S.2
  • 68
    • 0028246112 scopus 로고
    • Evidence that the clonogenic cell in multiple myeloma originates from a pre-switched but somatically mutated B cell
    • Bakkus M. H. C., van Riet I., van Camp B., Thielemans K., Evidence that the clonogenic cell in multiple myeloma originates from a pre-switched but somatically mutated B cell. British Journal of Haematology 1994 87 1 68 74 2-s2.0-0028246112 (Pubitemid 24207001)
    • (1994) British Journal of Haematology , vol.87 , Issue.1 , pp. 68-74
    • Bakkus, M.H.C.1    Van Riet, I.2    Van Camp, B.3    Thielemans, K.4
  • 69
    • 0036794974 scopus 로고    scopus 로고
    • + hematopoietic progenitors
    • Pilarski L. M., Belch A. R., Clonotypic myeloma cells able to xenograft myeloma to nonobese diabetic severe combined immunodeficient mice copurify with CD34+ hematopoietic progenitors. Clinical Cancer Research 2002 8 10 3198 3204 2-s2.0-0036794974 (Pubitemid 35155031)
    • (2002) Clinical Cancer Research , vol.8 , Issue.10 , pp. 3198-3204
    • Pilarski, L.M.1    Belch, A.R.2
  • 70
    • 1542283717 scopus 로고    scopus 로고
    • Characterization of clonogenic multiple myeloma cells
    • DOI 10.1182/blood-2003-09-3064
    • Matsui W., Huff C. A., Wang Q., Malehorn M. T., Barber J., Tanhehco Y., Smith B. D., Civin C. I., Jones R. J., Characterization of clonogenic multiple myeloma cells. Blood 2004 103 6 2332 2336 2-s2.0-1542283717 10.1182/blood-2003- 09-3064 (Pubitemid 38326254)
    • (2004) Blood , vol.103 , Issue.6 , pp. 2332-2336
    • Matsui, W.1    Huff, C.A.2    Wang, Q.3    Malehorn, M.T.4    Barber, J.5    Tanhehco, Y.6    Smith, B.D.7    Civin, C.I.8    Jones, R.J.9
  • 71
    • 0030934954 scopus 로고    scopus 로고
    • Myeloma stem cell phenotype: Implications for treatment
    • DOI 10.1016/S0889-8588(05)70414-7
    • Epstein J., Myeloma stem cell phenotype: implications for treatment. Hematology/Oncology Clinics of North America 1997 11 1 43 49 2-s2.0-0030934954 10.1016/S0889-8588(05)70414-7 (Pubitemid 27147745)
    • (1997) Hematology/Oncology Clinics of North America , vol.11 , Issue.1 , pp. 43-49
    • Epstein, J.1
  • 72
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • Gottesman M. M., Fojo T., Bates S. E., Multidrug resistance in cancer: role of ATP-dependent transporters. Nature Reviews Cancer 2002 2 1 48 58 2-s2.0-0036364467 (Pubitemid 37328807)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.1 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 73
    • 84884327949 scopus 로고    scopus 로고
    • Clonogenic multiple myeloma cells have shared stemness signature assocuated with patient survival
    • Reghunathan R., Bi C., Liu S. C., Clonogenic multiple myeloma cells have shared stemness signature assocuated with patient survival. Oncotarget 2013 4 1230 1240
    • (2013) Oncotarget , vol.4 , pp. 1230-1240
    • Reghunathan, R.1    Bi, C.2    Liu, S.C.3
  • 74
    • 0033664107 scopus 로고    scopus 로고
    • The clonal hierachy in multiple myeloma
    • Rasmussen T., Jensen L., Johnsen H. E., The clonal hierachy in multiple myeloma. Acta Oncologica 2000 39 7 765 770
    • (2000) Acta Oncologica , vol.39 , Issue.7 , pp. 765-770
    • Rasmussen, T.1    Jensen, L.2    Johnsen, H.E.3
  • 77
    • 84883625365 scopus 로고    scopus 로고
    • Xbp1s-negative tumor B cells and pre-plasmablasts mediate therapeutic proteasome inhibitor resistance in multiple myeloma
    • Leung-Hagesteijn C., Erdmann N., Cheung G., Xbp1s-negative tumor B cells and pre-plasmablasts mediate therapeutic proteasome inhibitor resistance in multiple myeloma. Cancer Cell 2013 24 289 304
    • (2013) Cancer Cell , vol.24 , pp. 289-304
    • Leung-Hagesteijn, C.1    Erdmann, N.2    Cheung, G.3
  • 78
    • 84886819205 scopus 로고    scopus 로고
    • RARalpha2 expression confers myeloma stem cell features
    • Yang Y., Shi J., Tolomelli G., RARalpha2 expression confers myeloma stem cell features. Blood 2013 122 1437 1447
    • (2013) Blood , vol.122 , pp. 1437-1447
    • Yang, Y.1    Shi, J.2    Tolomelli, G.3
  • 79
    • 84864458523 scopus 로고    scopus 로고
    • Identification of pluripotent and adult stem cell genes unrelated to cell cycle and associated with poor prognosis in multiple myeloma
    • 2-s2.0-84864458523 10.1371/journal.pone.0042161 e42161
    • Kassambara A., Hose D., Moreaux J., Rème T., Torrent J., Rossi J. F., Goldschmidt H., Klein B., Identification of pluripotent and adult stem cell genes unrelated to cell cycle and associated with poor prognosis in multiple myeloma. PLoS ONE 2012 7 7 2-s2.0-84864458523 10.1371/journal.pone.0042161 e42161
    • (2012) PLoS ONE , vol.7 , Issue.7
    • Kassambara, A.1    Hose, D.2    Moreaux, J.3    Rème, T.4    Torrent, J.5    Rossi, J.F.6    Goldschmidt, H.7    Klein, B.8
  • 81
    • 84883872187 scopus 로고    scopus 로고
    • Minimal residual disease assessed by multiparameter flow cytometry in multiple myeloma: Impact on outcome in the Medical Research Council Myeloma IX Study
    • Rawstron A. C., Child J. A., de Tute R. M., Minimal residual disease assessed by multiparameter flow cytometry in multiple myeloma: impact on outcome in the Medical Research Council Myeloma IX Study. Journal of Clinical Oncology 2013 31 2540 2547
    • (2013) Journal of Clinical Oncology , vol.31 , pp. 2540-2547
    • Rawstron, A.C.1    Child, J.A.2    De Tute, R.M.3
  • 82
    • 27144546033 scopus 로고    scopus 로고
    • Minimal residual disease monitoring in multiple myeloma: A comparison between allelic-specific oligonucleotide real-time quantitative polymerase chain reaction and flow cytometry
    • Sarasquete M. E., García-Sanz R., González D., Martínez J., Mateo G., Martínez P., Ribera J. M., Hernández J. M., Lahuerta J. J., Orfão A., González M., San Miguel J. F., Minimal residual disease monitoring in multiple myeloma: a comparison between allelic-specific oligonucleotide real-time quantitative polymerase chain reaction and flow cytometry. Haematologica 2005 90 10 1365 1372 2-s2.0-27144546033 (Pubitemid 41503652)
    • (2005) Haematologica , vol.90 , Issue.10 , pp. 1365-1372
    • Sarasquete, M.E.1    Garcia-Sanz, R.2    Gonzalez, D.3    Martinez, J.4    Mateo, G.5    Martinez, P.6    Ribera, J.M.7    Hernandez, J.M.8    Lahuerta, J.J.9    Orfao, A.10    Gonzalez, M.11    San Miguel, J.F.12
  • 87
    • 77958584577 scopus 로고    scopus 로고
    • Telomerase inhibition targets clonogenic multiple myeloma cells through telomere length-dependent and independent Mechanisms
    • 2-s2.0-77958584577 10.1371/journal.pone.0012487 e12487
    • Brennan S. K., Wang Q., Tressler R., Harley C., Go N., Bassett E., Huff C. A., Jones R. J., Matsui W., Telomerase inhibition targets clonogenic multiple myeloma cells through telomere length-dependent and independent Mechanisms. PLoS ONE 2010 5 9 2-s2.0-77958584577 10.1371/journal.pone.0012487 e12487
    • (2010) PLoS ONE , vol.5 , Issue.9
    • Brennan, S.K.1    Wang, Q.2    Tressler, R.3    Harley, C.4    Go, N.5    Bassett, E.6    Huff, C.A.7    Jones, R.J.8    Matsui, W.9
  • 89
    • 84863908333 scopus 로고    scopus 로고
    • Natural killer cell lines preferentially kill clonogenic multiple myeloma cells and decrease myeloma engraftment in a bioluminescent xenograft mouse model
    • 2-s2.0-84863908333 10.3324/haematol.2011.054254
    • Swift B. E., Williams B. A., Kosaka Y., Wang X.-H., Medin J. A., Viswanathan S., Martinez-Lopez J., Keating A., Natural killer cell lines preferentially kill clonogenic multiple myeloma cells and decrease myeloma engraftment in a bioluminescent xenograft mouse model. Haematologica 2012 97 7 1020 1028 2-s2.0-84863908333 10.3324/haematol.2011.054254
    • (2012) Haematologica , vol.97 , Issue.7 , pp. 1020-1028
    • Swift, B.E.1    Williams, B.A.2    Kosaka, Y.3    Wang, X.-H.4    Medin, J.A.5    Viswanathan, S.6    Martinez-Lopez, J.7    Keating, A.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.