Clozapine promotes the proliferation of granulocyte progenitors in the bone marrow leading to increased granulopoiesis and neutrophilia in rats

Chemical Research in Toxicology

Volumn 27, Issue 7, 2014, Pages 1109-1119

  Lobach, Alexandra R ^a   Uetrecht, Jack ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CD18 ANTIGEN; CLOZAPINE; GRANULOCYTE COLONY STIMULATING FACTOR; L SELECTIN; MACROPHAGE INFLAMMATORY PROTEIN 1; METHYLCELLULOSE; MYELOPEROXIDASE; NEUROLEPTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; BRDU ASSAY; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; COLONY FORMING UNIT M; CONTROLLED STUDY; DRUG HALF LIFE; FEMALE; GRANULOCYTE PRECURSOR; GRANULOPOIESIS; IN VIVO STUDY; LEUKOCYTE COUNT; NEUTROPHIL; NEUTROPHIL COUNT; NEUTROPHILIA; NONHUMAN; PROTEIN EXPRESSION; RAT; ANIMAL; CHEMICALLY INDUCED; CYTOLOGY; DRUG EFFECTS; LEUKOCYTE DISORDER; LEUKOPOIESIS; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIPSYCHOTIC AGENTS; BONE MARROW; CELL PROLIFERATION; CLOZAPINE; FEMALE; GRANULOCYTE PRECURSOR CELLS; LEUKOCYTE DISORDERS; LEUKOPOIESIS; RATS, SPRAGUE-DAWLEY;

EID: 84904632311     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx500184c     Document Type: Article

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