Development and validation of a sensitive ELISA for quantitation of Grastim® (rhG-CSF) in rat plasma: Application to a pharmacokinetic study

Biomedical Chromatography

Volumn 20, Issue 9, 2006, Pages 945-950

  Nirmala, Chandrasekar ^a   Trivedi, Ravikumar ^a   Prasanthi, Penubaka Venkata ^a   Mullangi, Ramesh ^a   Srinivas, Nuggehally R ^a  

^a DR REDDY'S LABORATORIES LTD   (India)

Author keywords

ELISA; G CSF; Grastim ; Pharmacokinetics; Rat plasma; Validation

Indexed keywords

BIOACTIVITY; BODY FLUIDS; PLASMA STABILITY; PROTEINS; RATS;

CONTROL SAMPLES; ENZYME LINKED IMMUNOSORBENT ASSAY; GRANULOCYTE-COLONY STIMULATING FACTOR; GRASTIM®; LOWER LIMITS OF QUANTITATIONS; MEASUREMENTS OF; PHARMACOKINETIC STUDIES; RAT PLASMA; RELATIVE STANDARDS DEVIATIONS; VALIDATION;

PHARMACOKINETICS;

GRASTIM; PROTEIN ANTIBODY; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ACCURACY; ADSORPTION; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; DISTRIBUTION VOLUME; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG STABILITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FREEZING; MALE; NONHUMAN; QUALITY CONTROL; QUANTITATIVE ANALYSIS; RAT; RELIABILITY; SENSITIVITY AND SPECIFICITY; STORAGE; THAWING; VALIDATION PROCESS;

EID: 33748944858     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.625     Document Type: Article

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