메뉴 건너뛰기




Volumn 32, Issue 5, 2014, Pages 564-569

Molecular pathogenesis of cholangiocarcinoma

Author keywords

Cancer associated fibroblast; Cholangiocarcinoma; Inflammation; Tumor microenvironment

Indexed keywords

ANGIOGENESIS; APOPTOSIS; ARTICLE; BILE DUCT CARCINOMA; CARCINOGENESIS; CELL PROLIFERATION; DNA DAMAGE; EPIGENETICS; FIBROBLAST; GENE MUTATION; HUMAN; INFLAMMATION; MOLECULAR PATHOLOGY; NONHUMAN; PRIMARY SCLEROSING CHOLANGITIS; PRIORITY JOURNAL; RISK FACTOR; STROMA; TUMOR ASSOCIATED LEUKOCYTE; TUMOR INVASION; ANIMAL; BILE DUCT TUMOR; GENETIC EPIGENESIS; GENETICS; INTRAHEPATIC BILE DUCT; PATHOLOGY; BILIARY TRACT INFLAMMATION; CANCER ASSOCIATED FIBROBLAST; CHRONIC INFLAMMATION; CONFERENCE PAPER; ENZYME INHIBITION; EXPERIMENTAL MODEL; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT;

EID: 84904612083     PISSN: 02572753     EISSN: 14219875     Source Type: Journal    
DOI: 10.1159/000360502     Document Type: Article
Times cited : (31)

References (44)
  • 1
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: Back to Virchow?
    • Balkwill F, Mantovani A: Inflammation and cancer: back to Virchow? Lancet 2001; 357: 539-545.
    • (2001) Lancet , vol.357 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 2
    • 84881458405 scopus 로고    scopus 로고
    • Barrett esophagus and risk of esophageal cancer: A clinical review
    • Spechler SJ: Barrett esophagus and risk of esophageal cancer: a clinical review. JAMA 2013; 310: 627-636.
    • (2013) JAMA , vol.310 , pp. 627-636
    • Spechler, S.J.1
  • 3
    • 84876787550 scopus 로고    scopus 로고
    • The epidemiology of pancreatitis and pancreatic cancer
    • Yadav D, Lowenfels AB: The epidemiology of pancreatitis and pancreatic cancer. Gastroenterology 2013; 144: 1252-1261.
    • (2013) Gastroenterology , vol.144 , pp. 1252-1261
    • Yadav, D.1    Lowenfels, A.B.2
  • 4
    • 34447092208 scopus 로고    scopus 로고
    • Immunology of Helicobacter pylori : Insights into the failure of the immune response and perspectives on vaccine studies
    • Wilson KT, Crabtree JE: Immunology of Helicobacter pylori : insights into the failure of the immune response and perspectives on vaccine studies. Gastroenterology 2007; 133: 288-308.
    • (2007) Gastroenterology , vol.133 , pp. 288-308
    • Wilson, K.T.1    Crabtree, J.E.2
  • 5
    • 79955564023 scopus 로고    scopus 로고
    • Intestinal inflammation and cancer
    • Ullman TA, Itzkowitz SH: Intestinal inflammation and cancer. Gastroenterology 2011; 140: 1807-1816.
    • (2011) Gastroenterology , vol.140 , pp. 1807-1816
    • Ullman, T.A.1    Itzkowitz, S.H.2
  • 6
    • 0033969322 scopus 로고    scopus 로고
    • Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism
    • Jaiswal M, LaRusso NF, Burgart LJ, Gores GJ: Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism. Cancer Res 2000; 60: 184-190.
    • (2000) Cancer Res , vol.60 , pp. 184-190
    • Jaiswal, M.1    Larusso, N.F.2    Burgart, L.J.3    Gores, G.J.4
  • 7
    • 20444452357 scopus 로고    scopus 로고
    • Interleukin-6 contributes to Mcl-1 up-regulation and trail resistance via an Akt-signaling pathway in cholangiocarcinoma cells
    • Kobayashi S, Werneburg NW, Bronk SF, Kaufmann SH, Gores GJ: Interleukin-6 contributes to Mcl-1 up-regulation and trail resistance via an Akt-signaling pathway in cholangiocarcinoma cells. Gastroenterology 2005; 128: 2054-2065.
    • (2005) Gastroenterology , vol.128 , pp. 2054-2065
    • Kobayashi, S.1    Werneburg, N.W.2    Bronk, S.F.3    Kaufmann, S.H.4    Gores, G.J.5
  • 8
    • 7244220245 scopus 로고    scopus 로고
    • Enhanced epidermal growth factor receptor activation in human cholangiocarcinoma cells
    • Yoon JH, Gwak GY, Lee HS, Bronk SF, Werneburg NW, Gores GJ: Enhanced epidermal growth factor receptor activation in human cholangiocarcinoma cells. J Hepatol 2004; 41: 808-814.
    • (2004) J Hepatol , vol.41 , pp. 808-814
    • Yoon, J.H.1    Gwak, G.Y.2    Lee, H.S.3    Bronk, S.F.4    Werneburg, N.W.5    Gores, G.J.6
  • 9
    • 0034110586 scopus 로고    scopus 로고
    • Unique epithelial cell production of hepatocyte growth factor/scatter factor by putative precancerous intestinal metaplasias and associated 'intestinal-type' biliary cancer chemically induced in rat liver
    • Lai GH, Radaeva S, Nakamura T, Sirica AE: Unique epithelial cell production of hepatocyte growth factor/scatter factor by putative precancerous intestinal metaplasias and associated 'intestinal-type' biliary cancer chemically induced in rat liver. Hepatology 2000; 31: 1257-1265.
    • (2000) Hepatology , vol.31 , pp. 1257-1265
    • Lai, G.H.1    Radaeva, S.2    Nakamura, T.3    Sirica, A.E.4
  • 10
    • 0036208350 scopus 로고    scopus 로고
    • Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line
    • Yoon JH, Higuchi H, Werneburg NW, Kaufmann SH, Gores GJ: Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line. Gastroenterology 2002; 122: 985-993.
    • (2002) Gastroenterology , vol.122 , pp. 985-993
    • Yoon, J.H.1    Higuchi, H.2    Werneburg, N.W.3    Kaufmann, S.H.4    Gores, G.J.5
  • 11
    • 1542724860 scopus 로고    scopus 로고
    • Oxysterols induce cyclooxygenase-2 expression in cholangiocytes: Implications for biliary tract carcinogenesis
    • Yoon JH, Canbay AE, Werneburg NW, Lee SP, Gores GJ: Oxysterols induce cyclooxygenase-2 expression in cholangiocytes: implications for biliary tract carcinogenesis. Hepatology 2004; 39: 732-738.
    • (2004) Hepatology , vol.39 , pp. 732-738
    • Yoon, J.H.1    Canbay, A.E.2    Werneburg, N.W.3    Lee, S.P.4    Gores, G.J.5
  • 12
    • 84870879515 scopus 로고    scopus 로고
    • Classification, diagnosis, and management of cholangiocarcinoma
    • e11 quiz e13-e14
    • Razumilava N, Gores GJ: Classification, diagnosis, and management of cholangiocarcinoma. Clin Gastroenterol Hepatol 2013; 11: 13- 21.e11; quiz e13-e14.
    • (2013) Clin Gastroenterol Hepatol , vol.11 , pp. 13-21
    • Razumilava, N.1    Gores, G.J.2
  • 14
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA: The hallmarks of cancer. Cell 2000; 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 15
    • 84875237481 scopus 로고    scopus 로고
    • Intrahepatic cholangiocarcinoma: Pathogenesis and rationale for molecular therapies
    • Sia D, Tovar V, Moeini A, Llovet JM: Intrahepatic cholangiocarcinoma: pathogenesis and rationale for molecular therapies. Oncogene 2013; 32: 4861-4870.
    • (2013) Oncogene , vol.32 , pp. 4861-4870
    • Sia, D.1    Tovar, V.2    Moeini, A.3    Llovet, J.M.4
  • 16
    • 0035170217 scopus 로고    scopus 로고
    • Nitric oxide-mediated inhibition of DNA repair potentiates oxidative DNA damage in cholangiocytes
    • Jaiswal M, LaRusso NF, Shapiro RA, Billiar TR, Gores GJ: Nitric oxide-mediated inhibition of DNA repair potentiates oxidative DNA damage in cholangiocytes. Gastroenterology 2001; 120: 190-199.
    • (2001) Gastroenterology , vol.120 , pp. 190-199
    • Jaiswal, M.1    Larusso, N.F.2    Shapiro, R.A.3    Billiar, T.R.4    Gores, G.J.5
  • 17
    • 84869424461 scopus 로고    scopus 로고
    • Mechanisms of oxysterol-induced disease: Insights from the biliary system
    • Kuver R: Mechanisms of oxysterol-induced disease: insights from the biliary system. Clin Lipidol 2012; 7: 537-548.
    • (2012) Clin Lipidol , vol.7 , pp. 537-548
    • Kuver, R.1
  • 18
    • 0034957745 scopus 로고    scopus 로고
    • Identification of oxysterols in human bile and pigment gallstones
    • Haigh WG, Lee SP: Identification of oxysterols in human bile and pigment gallstones. Gastroenterology 2001; 121: 118-123.
    • (2001) Gastroenterology , vol.121 , pp. 118-123
    • Haigh, W.G.1    Lee, S.P.2
  • 20
    • 33744788672 scopus 로고    scopus 로고
    • Oxysterols stimulate sonic hedgehog signal transduction and proliferation of medulloblastoma cells
    • Corcoran RB, Scott MP: Oxysterols stimulate sonic hedgehog signal transduction and proliferation of medulloblastoma cells. Proc Natl Acad Sci USA 2006; 103: 8408-8413.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 8408-8413
    • Corcoran, R.B.1    Scott, M.P.2
  • 21
    • 34247844371 scopus 로고    scopus 로고
    • Oxysterols are novel activators of the hedgehog signaling pathway in pluripotent mesenchymal cells
    • Dwyer JR, Sever N, Carlson M, Nelson SF, Beachy PA, Parhami F: Oxysterols are novel activators of the hedgehog signaling pathway in pluripotent mesenchymal cells. J Biol Chem 2007; 282: 8959-8968.
    • (2007) J Biol Chem , vol.282 , pp. 8959-8968
    • Dwyer, J.R.1    Sever, N.2    Carlson, M.3    Nelson, S.F.4    Beachy, P.A.5    Parhami, F.6
  • 22
    • 84883185477 scopus 로고    scopus 로고
    • Oxysterol binding to the extracellular domain of smoothened in hedgehog signaling
    • Nedelcu D, Liu J, Xu Y, Jao C, Salic A: Oxysterol binding to the extracellular domain of smoothened in hedgehog signaling. Nat Chem Biol 2013; 9: 557-564.
    • (2013) Nat Chem Biol , vol.9 , pp. 557-564
    • Nedelcu, D.1    Liu, J.2    Xu, Y.3    Jao, C.4    Salic, A.5
  • 23
  • 24
    • 0033150246 scopus 로고    scopus 로고
    • Chromosome 9p21 loss and p16 inactivation in primary sclerosing cholangitis-associated cholangiocarcinoma
    • Ahrendt SA, Eisenberger CF, Yip L, Rashid A, Chow JT, Pitt HA, Sidransky D: Chromosome 9p21 loss and p16 inactivation in primary sclerosing cholangitis-associated cholangiocarcinoma. J Surg Res 1999; 84: 88-93.
    • (1999) J Surg Res , vol.84 , pp. 88-93
    • Ahrendt, S.A.1    Eisenberger, C.F.2    Yip, L.3    Rashid, A.4    Chow, J.T.5    Pitt, H.A.6    Sidransky, D.7
  • 28
    • 77649334087 scopus 로고    scopus 로고
    • IDH1 and IDH2: Not your typical oncogenes
    • Reitman ZJ, Parsons DW, Yan H: IDH1 and IDH2: Not your typical oncogenes. Cancer Cell 2010; 17: 215-216.
    • (2010) Cancer Cell , vol.17 , pp. 215-216
    • Reitman, Z.J.1    Parsons, D.W.2    Yan, H.3
  • 31
    • 34848815007 scopus 로고    scopus 로고
    • Diagnostic utility of interleukin-6 (IL-6) for primary bile duct cancer and changes in serum IL-6 levels following photodynamic therapy
    • Cheon YK, Cho YD, Moon JH, Jang JY, Kim YS, Lee MS, Lee JS, Shim CS: Diagnostic utility of interleukin-6 (IL-6) for primary bile duct cancer and changes in serum IL-6 levels following photodynamic therapy. Am J Gastroenterol 2007; 102: 2164-2170.
    • (2007) Am J Gastroenterol , vol.102 , pp. 2164-2170
    • Cheon, Y.K.1    Cho, Y.D.2    Moon, J.H.3    Jang, J.Y.4    Kim, Y.S.5    Lee, M.S.6    Lee, J.S.7    Shim, C.S.8
  • 33
    • 36849017497 scopus 로고    scopus 로고
    • IL-6 involvement in epithelial cancers
    • Schafer ZT, Brugge JS: IL-6 involvement in epithelial cancers. J Clin Invest 2007; 117: 3660-3663.
    • (2007) J Clin Invest , vol.117 , pp. 3660-3663
    • Schafer, Z.T.1    Brugge, J.S.2
  • 37
    • 78649873560 scopus 로고    scopus 로고
    • Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: Insights into Alagille syndrome
    • Hofmann JJ, Zovein AC, Koh H, Radtke F, Weinmaster G, Iruela-Arispe ML: Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: Insights into Alagille syndrome. Development 2010; 137: 4061-4072.
    • (2010) Development , vol.137 , pp. 4061-4072
    • Hofmann, J.J.1    Zovein, A.C.2    Koh, H.3    Radtke, F.4    Weinmaster, G.5    Iruela-Arispe, M.L.6
  • 38
    • 19044383947 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase up-regulates NOTCH-1 in mouse cholangiocytes: Implications for carcinogenesis
    • Ishimura N, Bronk SF, Gores GJ: Inducible nitric oxide synthase up-regulates NOTCH-1 in mouse cholangiocytes: implications for carcinogenesis. Gastroenterology 2005; 128: 1354-1368.
    • (2005) Gastroenterology , vol.128 , pp. 1354-1368
    • Ishimura, N.1    Bronk, S.F.2    Gores, G.J.3
  • 40
    • 84655169986 scopus 로고    scopus 로고
    • The role of cancer-associated myofibroblasts in intrahepatic cholangiocarcinoma
    • Sirica AE: The role of cancer-associated myofibroblasts in intrahepatic cholangiocarcinoma. Nat Rev Gastroenterol Hepatol 2012; 9: 44-54.
    • (2012) Nat Rev Gastroenterol Hepatol , vol.9 , pp. 44-54
    • Sirica, A.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.