PM10-stimulated airway epithelial cells activate primary human dendritic cells independent of uric acid: Application of an in vitro model system exposing dendritic cells to airway epithelial cell-conditioned media

Respirology

Volumn 19, Issue 6, 2014, Pages 881-890

  Hirota, Jeremy A ^a,b   Alexis, Neil E ^c   Pui, Mandy ^b   Wong, Szewing ^b   Fung, Elkie ^b   Hansbro, Phillip ^d   Knight, Darryl A ^d   Sin, Don D ^a   Carlsten, Chris ^b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b VANCOUVER GENERAL HOSPITAL   (Canada)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

^d UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

air pollution; airway epithelial cell; dendritic cell; mucosal immunology; PM10

Indexed keywords

COLONY STIMULATING FACTOR; INTERLEUKIN 4; PHORBOL 13 ACETATE 12 MYRISTATE; URIC ACID; CULTURE MEDIUM; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; PARTICULATE MATTER;

AIR POLLUTION; ARTICLE; CELL CULTURE; CELL FUSION; CONTROLLED STUDY; DENDRITIC CELL; ENVIRONMENTAL EXPOSURE; EPITHELIUM CELL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATORY CELL; MEDIATOR; MONOCYTE; PARTICULATE MATTER; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; SUPERNATANT; URBAN AREA; ADULT; BIOLOGICAL MODEL; CELL DIFFERENTIATION; CULTURE MEDIUM; DRUG EFFECTS; MALE; METABOLISM; PATHOLOGY; PHARMACOLOGY; REPRODUCIBILITY; RESPIRATORY SYSTEM;

ADULT; CELL DIFFERENTIATION; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; DENDRITIC CELLS; EPITHELIAL CELLS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; IN VITRO TECHNIQUES; INTERLEUKIN-4; MALE; MODELS, BIOLOGICAL; PARTICULATE MATTER; PHENOTYPE; REPRODUCIBILITY OF RESULTS; RESPIRATORY SYSTEM; URIC ACID;

EID: 84904575621     PISSN: 13237799     EISSN: 14401843     Source Type: Journal    
DOI: 10.1111/resp.12316     Document Type: Article

References (45)

1. Hirota JA, Knight DA,. Human airway epithelial cell innate immunity: relevance to asthma. Curr. Opin. Immunol. 2013; 24: 740-746.
2. Kato A, Schleimer RP,. Beyond inflammation: airway epithelial cells are at the interface of innate and adaptive immunity. Curr. Opin. Immunol. 2007; 19: 711-720.
3. Parker D, Prince A,. Innate immunity in the respiratory epithelium. Am. J. Respir. Cell Mol. Biol. 2011; 45: 189-201.
4. Proud D, Leigh R,. Epithelial cells and airway diseases. Immunol. Rev. 2012; 242: 186-204.
5. Hammad H, Lambrecht BN,. Dendritic cells and epithelial cells: linking innate and adaptive immunity in asthma. Nat. Rev. Immunol. 2008; 8: 193-204.
6. Lambrecht BN, Hammad H,. The airway epithelium in asthma. Nat. Med. 2012; 18: 684-692.
7. Dockery DW, Pope CA 3rd, Xu X, Spengler JD, Ware JH, Fay ME, Ferris BG Jr, Speizer FE,. An association between air pollution and mortality in six U.S. cities. N. Engl. J. Med. 1993; 329: 1753-1759.
8. Pope CA 3rd, Ezzati M, Dockery DW,. Fine-particulate air pollution and life expectancy in the United States. N. Engl. J. Med. 2009; 360: 376-386.
9. Bernstein JA, Alexis N, Barnes C, Bernstein IL, Nel A, Peden D, Diaz-Sanchez D, Tarlo SM, Williams PB,. Health effects of air pollution. J. Allergy Clin. Immunol. 2004; 114: 1116-1123.
10. Samet JM, Dominici F, Curriero FC, Coursac I, Zeger SL,. Fine particulate air pollution and mortality in 20 U.S. cities. N. Engl. J. Med. 1987-1994; 343: 1742-1749.
11. Hetland RB, Cassee FR, Lag M, Refsnes M, Dybing E, Schwarze PE,. Cytokine release from alveolar macrophages exposed to ambient particulate matter: heterogeneity in relation to size, city and season. Part. Fibre Toxicol. 2005; 2: 4.
12. Vincent R, Goegan P, Johnson G, Brook JR, Kumarathasan P, Bouthillier L, Burnett RT,. Regulation of promoter-CAT stress genes in HepG2 cells by suspensions of particles from ambient air. Fundam. Appl. Toxicol. 1997; 39: 18-32.
13. Namork E, Johansen BV, Lovik M,. Detection of allergens adsorbed to ambient air particles collected in four European cities. Toxicol. Lett. 2006; 165: 71-78.
14. Alexis NE, Lay JC, Zeman K, Bennett WE, Peden DB, Soukup JM, Devlin RB, Becker S,. Biological material on inhaled coarse fraction particulate matter activates airway phagocytes in vivo in healthy volunteers. J. Allergy Clin. Immunol. 2006; 117: 1396-1403.
15. Iskandar A, Andersen ZJ, Bonnelykke K, Ellermann T, Andersen KK, Bisgaard H,. Coarse and fine particles but not ultrafine particles in urban air trigger hospital admission for asthma in children. Thorax 2012; 67: 252-257.
16. Bleck B, Tse DB, Curotto de Lafaille MA, Zhang F, Reibman J,. Diesel exhaust particle-exposed human bronchial epithelial cells induce dendritic cell maturation and polarization via thymic stromal lymphopoietin. J. Clin. Immunol. 2008; 28: 147-156.
17. Bleck B, Tse DB, Gordon T, Ahsan MR, Reibman J,. Diesel exhaust particle-treated human bronchial epithelial cells upregulate Jagged-1 and OX40 ligand in myeloid dendritic cells via thymic stromal lymphopoietin. J. Immunol. 2010; 185: 6636-6645.
18. Bleck B, Tse DB, Jaspers I, Curotto de Lafaille MA, Reibman J,. Diesel exhaust particle-exposed human bronchial epithelial cells induce dendritic cell maturation. J. Immunol. 2006; 176: 7431-7437.
19. Reibman J, Hsu Y, Chen LC, Bleck B, Gordon T,. Airway epithelial cells release MIP-3alpha/CCL20 in response to cytokines and ambient particulate matter. Am. J. Respir. Cell Mol. Biol. 2003; 28: 648-654.
20. Hirota JA, Hirota SA, Warner SM, Stefanowicz D, Shaheen F, Beck PL, Macdonald JA, Hackett TL, Sin DD, Van Eeden S, et-al. The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter. J. Allergy Clin. Immunol. 2012; 129: 1116-1125.
21. Peden DB, Hohman R, Brown ME, Mason RT, Berkebile C, Fales HM, Kaliner MA,. Uric acid is a major antioxidant in human nasal airway secretions. Proc. Natl Acad. Sci. U.S.A. 1990; 87: 7638-7642.
22. Johnson RJ, Sautin YY, Oliver WJ, Roncal C, Mu W, Gabriela Sanchez-Lozada L, Rodriguez-Iturbe B, Nakagawa T, Benner SA,. Lessons from comparative physiology: could uric acid represent a physiologic alarm signal gone awry in western society? J. Comp. Physiol. [B.] 2009; 179: 67-76.
23. Orowan E,. The origin of man. Nature 1955; 175: 683-684.
24. Proctor P,. Similar functions of uric acid and ascorbate in man? Nature 1970; 228: 868.
25. Shi Y, Evans JE, Rock KL,. Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 2003; 425: 516-521.
26. Shi Y, Mucsi AD, Ng G,. Monosodium urate crystals in inflammation and immunity. Immunol. Rev. 2010; 233: 203-217.
27. Ng G, Sharma K, Ward SM, Desrosiers MD, Stephens LA, Schoel WM, Li T, Lowell CA, Ling CC, Amrein MW, et-al. Receptor-independent, direct membrane binding leads to cell-surface lipid sorting and Syk kinase activation in dendritic cells. Immunity 2008; 29: 807-818.
28. Kool M, Willart MA, van Nimwegen M, Bergen I, Pouliot P, Virchow JC, Rogers N, Osorio F, Reis e Sousa C, Hammad H, et-al. An unexpected role for uric acid as an inducer of T helper 2 cell immunity to inhaled antigens and inflammatory mediator of allergic asthma. Immunity 2011; 34: 527-540.
29. Ramirez RD, Sheridan S, Girard L, Sato M, Kim Y, Pollack J, Peyton M, Zou Y, Kurie JM, Dimaio JM, et-al. Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins. Cancer Res. 2004; 64: 9027-9034.
30. O'Neill DW, Bhardwaj N,. Differentiation of peripheral blood monocytes into dendritic cells. Curr Protoc Immunol. 2005; 67: 22F.4.1-22F.4.9
31. Fujii T, Hayashi S, Hogg JC, Vincent R, Van Eeden SF,. Particulate matter induces cytokine expression in human bronchial epithelial cells. Am. J. Respir. Cell Mol. Biol. 2001; 25: 265-271.
32. Dimitroulopoulou C, Ashmore MR, Byrne MA,. Modelling the contribution of passive smoking to Exposure to PM10 in UK homes. Indoor Built Environ. 2001; 10: 209-213.
33. Parry DE, Busse WW, Sukow KA, Dick CR, Swenson C, Gern JE,. Rhinovirus-induced PBMC responses and outcome of experimental infection in allergic subjects. J. Allergy Clin. Immunol. 2000; 105: 692-698.
34. Kam SH, Singh A, He JQ, Ruan J, Gauvreau GM, O'Byrne PM, Fitzgerald JM, Tebbutt SJ,. Peripheral blood gene expression changes during allergen inhalation challenge in atopic asthmatic individuals. J. Asthma 2012; 49: 219-226.
35. Kehrer JP,. The Haber-Weiss reaction and mechanisms of toxicity. Toxicology 2000; 149: 43-50.
36. Allakhverdi Z, Comeau MR, Jessup HK, Yoon BR, Brewer A, Chartier S, Paquette N, Ziegler SF, Sarfati M, Delespesse G,. Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells. J. Exp. Med. 2007; 204: 253-258.
37. Zhou B, Comeau MR, De Smedt T, Liggitt HD, Dahl ME, Lewis DB, Gyarmati D, Aye T, Campbell DJ, Ziegler SF,. Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice. Nat. Immunol. 2005; 6: 1047-1053.
38. Sung SS, Fu SM, Rose CE Jr, Gaskin F, Ju ST, Beaty SR,. A major lung CD103 (alphaE)-beta7 integrin-positive epithelial dendritic cell population expressing Langerin and tight junction proteins. J. Immunol. 2006; 176: 2161-2172.
39. Rate A, Upham JW, Bosco A, McKenna KL, Holt PG,. Airway epithelial cells regulate the functional phenotype of locally differentiating dendritic cells: implications for the pathogenesis of infectious and allergic airway disease. J. Immunol. 2009; 182: 72-83.
40. Boland S, Baeza-Squiban A, Fournier T, Houcine O, Gendron MC, Chevrier M, Jouvenot G, Coste A, Aubier M, Marano F,. Diesel exhaust particles are taken up by human airway epithelial cells in vitro and alter cytokine production. Am. J. Physiol. 1999; 276: L604-613.
41. Boland S, Bonvallot V, Fournier T, Baeza-Squiban A, Aubier M, Marano F,. Mechanisms of GM-CSF increase by diesel exhaust particles in human airway epithelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 2000; 278: L25-32.
42. Ohtoshi T, Takizawa H, Okazaki H, Kawasaki S, Takeuchi N, Ohta K, Ito K,. Diesel exhaust particles stimulate human airway epithelial cells to produce cytokines relevant to airway inflammation in vitro. J. Allergy Clin. Immunol. 1998; 101: 778-785.
43. Bleck B, Grunig G, Chiu A, Liu M, Gordon T, Kazeros A, Reibman J,. MicroRNA-375 regulation of thymic stromal lymphopoietin by diesel exhaust particles and ambient particulate matter in human bronchial epithelial cells. J. Immunol. 2013; 190: 3757-3763.
44. Porter M, Karp M, Killedar S, Bauer SM, Guo J, Williams D, Breysse P, Georas SN, Williams MA,. Diesel-enriched particulate matter functionally activates human dendritic cells. Am. J. Respir. Cell Mol. Biol. 2007; 37: 706-719.
45. Ishii H, Hayashi S, Hogg JC, Fujii T, Goto Y, Sakamoto N, Mukae H, Vincent R, van Eeden SF,. Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment. Respir. Res. 2005; 6: 87.