Multi-well microelectrode array recordings detect neuroactivity of ToxCast compounds

NeuroToxicology

Volumn 44, Issue , 2014, Pages 204-217

  Valdivia, Pablo ^a   Martin, Matt ^b   LeFew, William R ^b   Ross, James ^a   Houck, Keith A ^b   Shafer, Timothy J ^b  

^a AXION BIOSYSTEMS   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Electrophysiology; Microelectrode arrays; Screening; ToxCast

Indexed keywords

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHANE; 1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; ABAMECTIN; ALDICARB; ALLETHRIN; BIFENTHRIN; CARBARIL; CHLORDANE; CHLORPHENOTANE; CHLORPYRIFOS; CYFLUTHRIN; DIELDRIN; DIMETHYL SULFOXIDE; ENDOSULFAN; EUGENOL; FENVALERATE; FIPRONIL; HEPTACHLOR EPOXIDE; IMIDACLOPRID; ION CHANNEL; LINDANE; METHOXYCHLOR; NICOTINE; NICOTINIC ACID; PERMETHRIN; PHENYTOIN; PYRETHROID; UNINDEXED DRUG; NEONICOTINOID; CYTOTOXIN;

ARTICLE; BRAIN CELL CULTURE; COHORT ANALYSIS; CYTOTOXICITY; DRUG MECHANISM; HUMAN; MICROELECTRODE; NERVE CELL CULTURE; NERVE CELL NETWORK; NEUROTOXICITY; PRIORITY JOURNAL; BLOOD BRAIN BARRIER; ANIMAL; BRAIN CORTEX; CELL CULTURE; CYTOLOGY; DEVICES; DRUG EFFECTS; LONG EVANS RAT; NERVE CELL; PHYSIOLOGY; TOXICITY TESTING;

ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; CYTOTOXINS; MICROELECTRODES; NEURONS; RATS, LONG-EVANS; TOXICITY TESTS;

EID: 84904563593     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2014.06.012     Document Type: Article

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