In silico structural homology modelling and docking for assessment of pandemic potential of a novel H7N9 influenza virus and its ability to be neutralized by existing anti-hemagglutinin antibodies

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Rajapaksha, Harinda ^a   Petrovsky, Nikolai ^a,b  

^a VAXINE PTY LTD   (Australia)

^b FLINDERS UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

INFLUENZA VIRUS HEMAGGLUTININ; NEUTRALIZING ANTIBODY; RECEPTOR; SIALIC ACID RECEPTOR; UNCLASSIFIED DRUG; HEMAGGLUTININ, AVIAN INFLUENZA A VIRUS;

ARTICLE; BINDING AFFINITY; COMPUTER PREDICTION; COMPUTER SIMULATION; CRYSTAL STRUCTURE; INFLUENZA VIRUS A H5N1; INFLUENZA VIRUS A H7N9; MOLECULAR DOCKING; MOLECULAR MODEL; NONHUMAN; PANDEMIC; STRUCTURAL BIOINFORMATICS; STRUCTURAL HOMOLOGY; VIRUS NEUTRALIZATION; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; HUMAN; IMMUNOLOGY; INFLUENZA; MOLECULAR GENETICS; ORTHOMYXOVIRUS INFECTION; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; VIROLOGY;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, NEUTRALIZING; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; INFLUENZA A VIRUS, H7N9 SUBTYPE; INFLUENZA, HUMAN; MOLECULAR DOCKING SIMULATION; MOLECULAR SEQUENCE DATA; ORTHOMYXOVIRIDAE INFECTIONS; PANDEMICS; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT;

EID: 84904560296     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0102618     Document Type: Article

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