메뉴 건너뛰기




Volumn 142, Issue 1, 2014, Pages 121-132

High expression of the mismatch repair protein MSH6 is associated with poor patient survival in melanoma

Author keywords

Melanoma; Mismatch repair; MSH6; Survival

Indexed keywords

MESSENGER RNA; MISMATCH REPAIR PROTEIN PMS2; PROTEIN MLH1; PROTEIN MSH6;

EID: 84904545812     PISSN: 00029173     EISSN: 19437722     Source Type: Journal    
DOI: 10.1309/AJCPCX2D9YULBBLG     Document Type: Article
Times cited : (20)

References (46)
  • 1
    • 78049485263 scopus 로고    scopus 로고
    • Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
    • Ferlay J, Shin HR, Bray F, et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010;127:2893-2917.
    • (2010) Int J Cancer , vol.127 , pp. 2893-2917
    • Ferlay, J.1    Shin, H.R.2    Bray, F.3
  • 3
    • 74949143594 scopus 로고    scopus 로고
    • Final version of 2009 AJCC Melanoma Staging and Classification
    • Balch CM, Gershenwald JE, Soong SJ, et al. Final version of 2009 AJCC Melanoma Staging and Classification. J Clin Oncol. 2009;27:6199-6206.
    • (2009) J Clin Oncol , vol.27 , pp. 6199-6206
    • Balch, C.M.1    Gershenwald, J.E.2    Soong, S.J.3
  • 5
    • 84867313947 scopus 로고    scopus 로고
    • IFN-alpha in the treatment of melanoma
    • Tarhini AA, Gogas H, Kirkwood JM. IFN-alpha in the treatment of melanoma. J Immunol. 2012;189:3789-3793.
    • (2012) J Immunol , vol.189 , pp. 3789-3793
    • Tarhini, A.A.1    Gogas, H.2    Kirkwood, J.M.3
  • 6
    • 77955863455 scopus 로고    scopus 로고
    • Gene signature of the metastatic potential of cutaneous melanoma: Too much for too little?
    • Timar J, Gyorffy B, Raso E. Gene signature of the metastatic potential of cutaneous melanoma: too much for too little? Clin Exp Metastasis. 2010;27:371-387.
    • (2010) Clin Exp Metastasis , vol.27 , pp. 371-387
    • Timar, J.1    Gyorffy, B.2    Raso, E.3
  • 7
    • 84855947682 scopus 로고    scopus 로고
    • Review and cross-validation of gene expression signatures and melanoma prognosis
    • Schramm SJ, Campain AE, Scolyer RA, et al. Review and cross-validation of gene expression signatures and melanoma prognosis. J Invest Dermatol. 2012;132:274-283.
    • (2012) J Invest Dermatol , vol.132 , pp. 274-283
    • Schramm, S.J.1    Campain, A.E.2    Scolyer, R.A.3
  • 8
    • 33645739022 scopus 로고    scopus 로고
    • Gene expression profiling of primary cutaneous melanoma and clinical outcome
    • Winnepenninckx V, Lazar V, Michiels S, et al. Gene expression profiling of primary cutaneous melanoma and clinical outcome. J Natl Cancer Inst. 2006;98:472-482.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 472-482
    • Winnepenninckx, V.1    Lazar, V.2    Michiels, S.3
  • 11
    • 72549092925 scopus 로고    scopus 로고
    • Gene expression profiling of paraffin-embedded primary melanoma using the DASL assay identifies increased osteopontin expression as predictive of reduced relapse-free survival
    • Conway C, Mitra A, Jewell R, et al. Gene expression profiling of paraffin-embedded primary melanoma using the DASL assay identifies increased osteopontin expression as predictive of reduced relapse-free survival. Clin Cancer Res. 2009;15:6939-6946.
    • (2009) Clin Cancer Res , vol.15 , pp. 6939-6946
    • Conway, C.1    Mitra, A.2    Jewell, R.3
  • 12
    • 78049486226 scopus 로고    scopus 로고
    • Patterns of expression of DNA repair genes and relapse from melanoma
    • Jewell R, Conway C, Mitra A, et al. Patterns of expression of DNA repair genes and relapse from melanoma. Clin Cancer Res. 2010;16:5211-5221.
    • (2010) Clin Cancer Res , vol.16 , pp. 5211-5221
    • Jewell, R.1    Conway, C.2    Mitra, A.3
  • 13
    • 84864443974 scopus 로고    scopus 로고
    • Molecular profiling reveals low- and high-grade forms of primary melanoma
    • Harbst K, Staaf J, Lauss M, et al. Molecular profiling reveals low- and high-grade forms of primary melanoma. Clin Cancer Res. 2012;18:4026-4036.
    • (2012) Clin Cancer Res , vol.18 , pp. 4026-4036
    • Harbst, K.1    Staaf, J.2    Lauss, M.3
  • 14
    • 84874980924 scopus 로고    scopus 로고
    • A nine-gene signature predicting clinical outcome in cutaneous melanoma
    • Brunner G, Reitz M, Heinecke A, et al. A nine-gene signature predicting clinical outcome in cutaneous melanoma. J Cancer Res Clin Oncol. 2013;139:249-258.
    • (2013) J Cancer Res Clin Oncol , vol.139 , pp. 249-258
    • Brunner, G.1    Reitz, M.2    Heinecke, A.3
  • 15
    • 38049125557 scopus 로고    scopus 로고
    • Mechanisms and functions of DNA mismatch repair
    • Li GM. Mechanisms and functions of DNA mismatch repair. Cell Res. 2008;18:85-98.
    • (2008) Cell Res , vol.18 , pp. 85-98
    • Li, G.M.1
  • 16
    • 84860510016 scopus 로고    scopus 로고
    • Mammalian mismatch repair: Error-free or error-prone?
    • Pena-Diaz J, Jiricny J. Mammalian mismatch repair: error-free or error-prone? Trends Biochem Sci. 2012;37:206-214.
    • (2012) Trends Biochem Sci , vol.37 , pp. 206-214
    • Pena-Diaz, J.1    Jiricny, J.2
  • 19
    • 0034909244 scopus 로고    scopus 로고
    • Alterations of mismatch repair protein expression in benign melanocytic nevi, melanocytic dysplastic nevi, and cutaneous malignant melanomas
    • DOI 10.1097/00000372-200108000-00006
    • Hussein MR, Roggero E, Sudilovsky EC, et al. Alterations of mismatch repair protein expression in benign melanocytic nevi, melanocytic dysplastic nevi, and cutaneous malignant melanomas. Am J Dermatopathol. 2001;23:308-314. (Pubitemid 32729440)
    • (2001) American Journal of Dermatopathology , vol.23 , Issue.4 , pp. 308-314
    • Hussein, M.R.1    Roggero, E.2    Sudilovsky, E.C.3    Tuthill, R.J.4    Wood, G.S.5    Sudilovsky, O.6
  • 21
    • 84859239896 scopus 로고    scopus 로고
    • DNA repair mechanisms protect our genome from carcinogenesis
    • Moraes MC, Neto JB, Menck CF. DNA repair mechanisms protect our genome from carcinogenesis. Front Biosci. 2012;17:1362-1388.
    • (2012) Front Biosci , vol.17 , pp. 1362-1388
    • Moraes, M.C.1    Neto, J.B.2    Menck, C.F.3
  • 22
    • 48049100333 scopus 로고    scopus 로고
    • Overexpression of DNA repair genes is associated with metastasis: A new hypothesis
    • Sarasin A, Kauffmann A. Overexpression of DNA repair genes is associated with metastasis: a new hypothesis. Mutat Res. 2008;659:49-55.
    • (2008) Mutat Res , vol.659 , pp. 49-55
    • Sarasin, A.1    Kauffmann, A.2
  • 23
    • 0030915637 scopus 로고    scopus 로고
    • Decreased expression of MLH1, MSH2, PMS1 and PMS2 in pigmented lesions indicated accumulation of failed DNA repair along with malignant transformation and tumour progression
    • Korabiowska M, Dengler H, Kellner S, et al. Decreased expression of MLH1, MSH2, PMS1 and PMS2 in pigmented lesions indicates accumulation of failed DNA repair along with malignant transformation and tumour progression. Oncol Rep. 1997;4:653-655. (Pubitemid 27210217)
    • (1997) Oncology Reports , vol.4 , Issue.3 , pp. 653-655
    • Korabiowska, M.1    Dengler, H.2    Kellner, S.3    Stachura, J.4    Schauer, A.5
  • 24
    • 0035570139 scopus 로고    scopus 로고
    • DNA mismatch repair enzyme hMSH2 in malignant melanoma: Increased immunoreactivity as compared to acquired melanocytic nevi and strong mRNA expression in melanoma cell lines
    • DOI 10.1023/A:1014472314354
    • Rass K, Gutwein P, Welter C, et al. DNA mismatch repair enzyme hMSH2 in malignant melanoma: increased immunoreactivity as compared to acquired melanocytic nevi and strong mRNA expression in melanoma cell lines. Histochem J. 2001;33:459-467. (Pubitemid 34229663)
    • (2001) Histochemical Journal , vol.33 , Issue.8 , pp. 459-467
    • Rass, K.1    Gutwein, P.2    Welter, C.3    Meineke, V.4    Tilgen, W.5    Reichrath, J.6
  • 26
    • 84871142396 scopus 로고    scopus 로고
    • DNA repair and replication proteins as prognostic markers in melanoma
    • Song L, Robson T, Doig T, et al. DNA repair and replication proteins as prognostic markers in melanoma. Histopathology. 2013;62:343-350.
    • (2013) Histopathology , vol.62 , pp. 343-350
    • Song, L.1    Robson, T.2    Doig, T.3
  • 27
    • 0024312619 scopus 로고
    • Proliferative activity of cutaneous melanocytic tumors defined by Ki-67 monoclonal antibody. A quantitative immunohistochemical study
    • Smolle J, Soyer HP, Kerl H. Proliferative activity of cutaneous melanocytic tumors defined by Ki-67 monoclonal antibody: a quantitative immunohistochemical study. Am J Dermatopathol. 1989;11:301-307. (Pubitemid 19185400)
    • (1989) American Journal of Dermatopathology , vol.11 , Issue.4 , pp. 301-307
    • Smolle, J.1    Soyer, H.-P.2    Kerl, H.3
  • 31
    • 79953330774 scopus 로고    scopus 로고
    • Heterogeneous topographic profiles of kinetic and cell cycle regulator microsatellites in atypical (dysplastic) melanocytic nevi
    • Husain EA, Mein C, Pozo L, et al. Heterogeneous topographic profiles of kinetic and cell cycle regulator microsatellites in atypical (dysplastic) melanocytic nevi. Mod Pathol. 2011;24:471-486.
    • (2011) Mod Pathol , vol.24 , pp. 471-486
    • Husain, E.A.1    Mein, C.2    Pozo, L.3
  • 32
    • 41149122099 scopus 로고    scopus 로고
    • Comparison of pHH3, Ki-67, and survivin immunoreactivity in benign and malignant melanocytic lesions
    • DOI 10.1097/DAD.0b013e3181624054, PII 0000037220080400000005
    • Nasr MR, El-Zammar O. Comparison of pHH3, Ki-67, and survivin immunoreactivity in benign and malignant melanocytic lesions. Am J Dermatopathol. 2008;30:117-122. (Pubitemid 351441982)
    • (2008) American Journal of Dermatopathology , vol.30 , Issue.2 , pp. 117-122
    • Nasr, M.R.1    El-Zammar, O.2
  • 34
    • 84862001719 scopus 로고    scopus 로고
    • A seven-marker signature and clinical outcome in malignant melanoma: A large-scale tissue-microarray study with two independent patient cohorts
    • Meyer S, Fuchs TJ, Bosserhoff AK, et al. A seven-marker signature and clinical outcome in malignant melanoma: a large-scale tissue-microarray study with two independent patient cohorts. PLoS One. 2012;7:e38222.
    • (2012) PLoS One , vol.7
    • Meyer, S.1    Fuchs, T.J.2    Bosserhoff, A.K.3
  • 35
    • 63649143625 scopus 로고    scopus 로고
    • Tissue biomarkers for prognosis in cutaneous melanoma: A systematic review and meta-analysis
    • Gould Rothberg BE, Bracken MB, Rimm DL. Tissue biomarkers for prognosis in cutaneous melanoma: a systematic review and meta-analysis. J Natl Cancer Inst. 2009;101:452-474.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 452-474
    • Gould Rothberg, B.E.1    Bracken, M.B.2    Rimm, D.L.3
  • 37
    • 84877924574 scopus 로고    scopus 로고
    • Structural, molecular and cellular functions of MSH2 and MSH6 during DNA mismatch repair, damage signaling and other noncanonical activities
    • Edelbrock MA, Kaliyaperumal S, Williams KJ. Structural, molecular and cellular functions of MSH2 and MSH6 during DNA mismatch repair, damage signaling and other noncanonical activities. Mutat Res. 2013;743-744:53-66.
    • (2013) Mutat Res , vol.743-744 , pp. 53-66
    • Edelbrock, M.A.1    Kaliyaperumal, S.2    Williams, K.J.3
  • 38
    • 78149469118 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase with specific inhibitors as a strategy in cancer therapy
    • 6- methylguanine-DNA methyltransferase with specific inhibitors as a strategy in cancer therapy. Cell Mol Life Sci. 2010;67:3663-3681.
    • (2010) Cell Mol Life Sci , vol.67 , pp. 3663-3681
    • Kaina, B.1    Margison, G.P.2    Christmann, M.3
  • 39
    • 79960656490 scopus 로고    scopus 로고
    • 6-Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: Enzyme activity, promoter methylation and immunohistochemistry
    • 6-Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: enzyme activity, promoter methylation and immunohistochemistry. Biochim Biophys Acta. 2011;1816:179-190.
    • (2011) Biochim Biophys Acta , vol.1816 , pp. 179-190
    • Christmann, M.1    Verbeek, B.2    Roos, W.P.3
  • 40
    • 79956084544 scopus 로고    scopus 로고
    • Multifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools
    • Pegg AE. Multifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools. Chem Res Toxicol. 2011;24:618-639.
    • (2011) Chem Res Toxicol , vol.24 , pp. 618-639
    • Pegg, A.E.1
  • 41
    • 0031589755 scopus 로고    scopus 로고
    • 6-methylguanine in Mex-, Mex+ and methylation-tolerant mismatch repair compromised cells: Facts and models
    • 6-methylguanine in Mex-, Mex+ and methylation-tolerant mismatch repair compromised cells: facts and models. Mutat Res. 1997;381:227-241.
    • (1997) Mutat Res , vol.381 , pp. 227-241
    • Kaina, B.1    Ziouta, A.2    Ochs, K.3
  • 43
    • 0035266245 scopus 로고    scopus 로고
    • 2/M arrest and the fate of temozolomide-treated human glioblastoma cells
    • 2/M arrest and the fate of temozolomide-treated human glioblastoma cells. Cancer Res. 2001;61:1957-1963.
    • (2001) Cancer Res , vol.61 , pp. 1957-1963
    • Hirose, Y.1    Berger, M.S.2    Pieper, R.O.3
  • 44
    • 0242663968 scopus 로고    scopus 로고
    • 2 checkpoint and to resistance to chemotherapeutic DNA-methylating agents
    • 2 checkpoint and to resistance to chemotherapeutic DNA-methylating agents. Mol Cell Biol. 2003;23:8306-8315.
    • (2003) Mol Cell Biol , vol.23 , pp. 8306-8315
    • Hirose, Y.1    Katayama, M.2    Stokoe, D.3
  • 46
    • 2442670292 scopus 로고    scopus 로고
    • 2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase
    • 2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase. Genes Dev. 2004;18:1331-1344.
    • (2004) Genes Dev , vol.18 , pp. 1331-1344
    • Stojic, L.1    Mojas, N.2    Cejka, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.