An increased proportion of circulating Th22 and Tc22 cells in psoriasis

Cellular Immunology

Volumn 290, Issue 2, 2014, Pages 196-200

  Luan, Li ^a   Ding, Ying ^a   Han, Shixin ^a   Zhang, Zhenying ^b   Liu, Xiaoming ^a,b  

^a DALIAN MEDICAL UNIVERSITY   (China)

^b THE UNIVERSITY OF HONG KONG SHENZHEN HOSPITAL   (China)

Author keywords

AHR; IL 22; Psoriasis; Tc22 cell; Th22 cell

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; INTERLEUKIN 22; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; MALE; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PROTEIN EXPRESSION; PSORIASIS; PSORIASIS AREA AND SEVERITY INDEX; T LYMPHOCYTE; TC22 CELL; TH22 CELL; BIOSYNTHESIS; CD8+ T LYMPHOCYTE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HELPER CELL; IMMUNOLOGY; MIDDLE AGED; REAL TIME POLYMERASE CHAIN REACTION; T LYMPHOCYTE SUBPOPULATION;

ADULT; CD8-POSITIVE T-LYMPHOCYTES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMANS; INTERLEUKINS; MALE; MIDDLE AGED; PSORIASIS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, ARYL HYDROCARBON; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 84904480162     PISSN: 00088749     EISSN: 10902163     Source Type: Journal    
DOI: 10.1016/j.cellimm.2014.06.007     Document Type: Article

References (30)

1. Bos J.D. Psoriasis, innate immunity, and gene pools. J. Am. Acad. Dermatol. 2007, 56:468-471.
2. Nestle F.O., Kaplan D.H., Barker J. Psoriasis. N. Engl. J. Med. 2009, 361:496-509.
3. Austin L.M., Ozawa M., Kikuchi T., Walters I.B., Krueger J.G. The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: a type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients. J. Invest. Dermatol. 1999, 113:752-759.
4. Szabo S.K., Hammerberg C., Yoshida Y., Bata-Csorgo Z., Cooper K.D. Identification and quantitation of interferon-gamma producing T cells in psoriatic lesions: localization. 1998, 111:1072-1078.
5. Zhou X., Krueger J.G., Kao M.C., Lee E., Du F., Menter A., Wong W.H., et al. Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-element oligonucleotide array. Physiol. Genomics 2003, 13:69-78.
6. Lowes M.A., Kikuchi T., Fuentes-Duculan J., Cardinale I., Zaba L.C., Haider A.S., et al. Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells. J. Invest. Dermatol. 2008, 128:1207-1211.
7. Nograles K.E., Zaba L.C., Guttman-Yassky E., Fuentes-Duculan J., Suárez-Fariñas M., Cardinale I., et al. Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways. Br. J. Dermatol. 2008, 159:1092-1102.
8. Duhen T., Geiger R., Jarrossay D., Lanzavecchia A., Sallusto F. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat. Immunol. 2009, 10:857-863.
9. Trifari S., Kaplan C.D., Tran E.H., Crellin N.K., Spits H. Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells. Nat. Immunol. 2009, 10:864-871.
10. Zheng Y., Danilenko D.M., Valdez P., Kasman I., Eastham-Anderson J., Wu J., et al. Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature 2007, 445:648-651.
11. Boniface K., Bernard F.X., Garcia M., Gurney A.L., Lecron J.C., Morel F. IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes. J. Immunol. 2005, 174:3695-3702.
12. Wolk K., Witte E., Warszawska K., Schulze-Tanzil G., Witte K., Philipp S., et al. The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis. Eur. J. Immunol. 2009, 39:3570-3581.
13. Ouyang W. Distinct roles of IL-22 in human psoriasis and inflammatory bowel disease. Cytokine Growth Factor Rev. 2010, 21:435-441.
14. Kagami S., Rizzo H.L., Lee J.J., Koguchi Y., Blauvelt A. Circulating Th17, Th22, and Th1 cells are increased in psoriasis. J. Invest. Dermatol. 2010, 130:1373-1383.
15. Benham H., Norris P., Goodall J., et al. Th17 and Th22 cells in psoriatic arthritis and psoriasis. Arthritis Res. Ther. 2013, 26:R136.
16. Nograles K.E., Zaba L.C., Shemer A., et al. Activation of the aryl hydrocarbon receptor reveals distinct requirements for IL-22 and IL-17 production by human T helper cells. J. Allergy Clin. Immunol. 2009, 123:1244-1252.
17. Veldhoen M., Hirota K., Westendorf A.M., et al. The aryl hydrocarbon receptor links Th17-cell-mediated autoimmunity to environmental toxins. Nature 2008, 453:106.
18. Res P.C., Piskin G., de Boer O.J., van der Loos C.M., Teeling P., Bos J.D., et al. Overrepresentation of IL-17A and IL-22 producing CD8 T cells in lesional skin suggests their involvement in the pathogenesis of psoriasis. PLoS One 2010, 24:e14108.
19. Batista M.D., Tincati C., Milush J.M., Ho E.L., Ndhlovu L.C., York V.A., et al. CD57 expression and cytokine production by T cells in lesional and unaffected skin from patients with psoriasis. PLoS One 2013, 8:e52144.
20. + cells. Nat. Commun. 2013, 4:2112.
21. Pan H.F., Li X.P., Zheng S.G., et al. Emerging role of interleukin-22 in autoimmune diseases. Cytokine Growth Factor Rev. 2012, 24:51-57.
22. Eyerich S., Eyerich K., Pennino D., Carbone T., Nasorri F., Pallotta S., et al. Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling. J. Clin. Invest. 2009, 119:3573-3585.
23. Kolb H., Kolb-Bachofen V. Nitric oxide: a pathogenetic factor in autoimmunity. Immunol. Today 1992, 13:157-1601.
24. Jonuleit H., Dnop J., End A.H. Cytokines and their effects on maturation, differentiation and migration of dendritic cells. Arch. Dermatol. Res. 1996, 289:1.
25. Hijnen D., Knol E.F., Gent Y.Y., Giovannone B., Beijn S.J., Kupper T.S., et al. CD8(+) T cells in the lesional skin of atopic dermatitis and psoriasis patients are an important source of IFN-γ, IL-13, IL-17, and IL-22. J. Invest. Dermatol. 2013, 133:973-979.
26. Nograles K.E., Zaba L.C., Shemer A., et al. IL-22-producing "T22" T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells. J. Allergy Clin. Immunol. 2009, 123:1244-1252.
27. Gunderson A.J., Mohammed J., Horvath F.J., Podolsky M.A., Anderson C.R., Glick A.B. CD8(+) T cells mediate RAS-induced psoriasis-like skin inflammation through IFN-γ. J. Invest. Dermatol. 2013, 133:955-963.
28. Di Meglio P., Duarte J.H. CD8 T cells and IFN-γ emerge as critical players for psoriasis in a novel model of mouse psoriasiform skin inflammation. J. Invest. Dermatol. 2013, 133:871-874.
29. Hao J.Q. Targeting interleukin-22 in psoriasis. Inflammation 2014, 37:94-99.
30. Guilloteau K., Paris I., Pedretti N., Boniface K., Juchaux F., Huguier V., et al. Skin inflammation induced by the synergistic action of IL-17A, IL-22, oncostatin M, IL-1{alpha}, and TNF-{alpha} recapitulates some features of psoriasis. J. Immunol. 2010.