Proteotoxicity is not the reason for the dependence of cancer cells on the major chaperone Hsp70

Cell Cycle

Volumn 13, Issue 14, 2014, Pages 2306-2310

  Colvin, Teresa A ^a   Gabai, Vladimir L ^a   Sherman, Michael Y ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chaperone; Hsp70; Non oncogene addiction; Proteotoxic stress; Rational drug targeting

Indexed keywords

BORTEZOMIB; DOXORUBICIN; HEAT SHOCK PROTEIN 70;

ARTICLE; CANCER CELL; CANCER GROWTH; CELL AGING; CELL STRESS; CELL SURVIVAL; CONTROLLED STUDY; ENZYME SPECIFICITY; FEMALE; HELA CELL LINE; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MCF 7 CELL LINE; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; TOXICITY; BREAST TUMOR; DOWN REGULATION; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HEAT SHOCK RESPONSE; HEK293 CELL LINE; METABOLISM; PATHOLOGY; PROTEIN REFOLDING; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME; UTERINE CERVIX TUMOR;

BREAST NEOPLASMS; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEAT-SHOCK RESPONSE; HEK293 CELLS; HELA CELLS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MCF-7 CELLS; PROTEIN REFOLDING; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION; UTERINE CERVICAL NEOPLASMS;

EID: 84904479777     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.29296     Document Type: Article

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