Uncovering the roles of miRNAs and their relationship with androgen receptor in prostate cancer

IUBMB Life

Volumn 66, Issue 6, 2014, Pages 379-386

  Song, Chunjiao ^a   Huan, Chen ^b   Xu, Chaoyang ^a   Ru, Guomei ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b Zhejiang Institute of Microbiology   (China)

Author keywords

androgen receptor; castration resistant prostate cancer; miRNAs; prostate cancer; target genes

Indexed keywords

ANDROGEN RECEPTOR; MICRORNA;

DISEASE COURSE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MALE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; PROSTATE TUMOR;

DISEASE PROGRESSION; GENE EXPRESSION REGULATION; HUMANS; MALE; MICRORNAS; PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN;

EID: 84904469607     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.1281     Document Type: Review

References (43)

1. Lee, R. C., Feinbaum, R. L., and, Ambros, V., (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75, 843-854.
2. Kobayashi, T., Inoue, T., Kamba, T., and, Ogawa, O., (2013) Experimental evidence of persistent androgen-receptor-dependency in castration-resistant prostate cancer. Int. J. Mol. Sci. 14, 15615-15635.
3. Ozen, M., Creighton, C. J., Ozdemir, M., and, Ittmann, M., (2008) Widespread deregulation of microRNA expression in human prostate cancer. Oncogene 27, 1788-1793.
4. Ma, S., Chan, Y. P., Kwan, P. S., Lee, T. K., Yan, M., et al. (2011) MicroRNA-616 induces androgen-independent growth of prostate cancer cells by suppressing expression of tissue factor pathway inhibitor TFPI-2. Cancer Res. 71, 583-592.
5. Cheng, P., Li, R. S., Lin, B. Y., Lin, Y. H., Li, W., et al. (2009) Effect of miR-296 on the apoptosis of androgen-independent prostate cancer cells. J. Reprod. Contracep. 20, l-9.
6. Lin, S. L., Chiang, A., Chang, D., and, Ying, S. Y., (2008) Loss of miR-146a function in hormone-refractory prostate cancer. RNA 14, 417-424.
7. Fendler, A., Stephan, C., Yousef, G. M., and, Jung, K., (2011) MicroRNAs as regulators of signal transduction in urological tumors. Clin. Chem. 57, 954-968.
8. Narayanan, R., Jiang, J., Gusev, Y., Jones, A., Kearbey, J. D., et al. (2010) MicroRNAs are mediators of androgen action in prostate and muscle. PLoS One 5, e13637.
9. Jalava, S. E., Urbanucci, A., Latonen, L., Waltering, K. K., Sahu, B., et al. (2012) Androgen-regulated miR-32 targets BTG2 and is overexpressed in castration-resistant prostate cancer. Oncogene 31, 4460-4471.
10. Chu, M., Chang, Y., Li, P., Guo, Y., Zhang, K., et al. (2014) Androgen receptor is negatively correlated with the methylation-mediated transcriptional repression of miR-375 in human prostate cancer cells. Oncol. Rep. 31, 34-40.
11. Östling, P., Leivonen, S. K., Aakula, A., Kohonen, P., Mäkelä, R., et al. (2011) Systematic analysis of microRNAs targeting the androgen receptor in prostate cancer cells. Cancer Res. 71, 1956-1967.
12. Ribas, J., Ni, X., Haffner, M., Wentzel, E. A., Salmasi, A. H., et al. (2009) miR-21: An androgen receptor-regulated microRNA that promotes hormone-dependent and hormone-independent prostate cancer growth. Cancer Res. 69, 7165-7169.
13. Sikand, K., Slaibi, J. E., Singh, R., Slane, S. D., and, Shukla, G. C., (2011) miR 488* inhibits androgen receptor expression in prostate carcinoma cells. Int. J. Cancer 129, 810-819.
14. Li, T., Li, D., Sha, J., Sun, P., and, Huang, Y., (2009) MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells. Biochem Biophys Res Commun. 383, 280-285.
15. Mishra, S., Deng, J. J., Gowda, P. S., Rao, M. K., Lin, C. L., et al. (2013) Androgen receptor and microRNA-21 axis downregulates transforming growth factor beta receptor II (TGFBR2) expression in prostate cancer. Oncogene.
16. Folini, M., Gandellini, P., Longoni, N., Profumo, V., Callari, M., et al. (2010) miR-21: An oncomir on strike in prostate cancer. Mol. Cancer 9, 12.
17. Linsley, P. S., Schelter, J., Burchard, J., Kibukawa, M., Martin, M. M., et al. (2007) Transcripts targeted by the microRNA-l6 family cooperatively regulate cell cycle progession. Mol. Cell Biol. 27, 2240-2252.
18. Xiao, J., Gong, A. Y., Eischeid, A. N., Chen, D., Deng, C., et al. (2012) miR-141 modulates androgen receptor transcriptional activity in human prostate cancer cells through targeting the small heterodimer partner protein. Prostate 72, 1514-1522.
19. Waltering, K. K., Porkka, K. P., Jalava, S. E., Urbanucci, A., Kohonen, P. J., et al. (2011) Androgen regulation of micro-RNAs in prostate cancer. Prostate 71, 604-614.
20. Sun, D., Layer, R., Mueller, A. C., Cichewicz, M. A., Negishi, M., et al. (2014) Regulation of several androgen-induced genes through the repression of the miR-99a/let-7c/miR-125b-2 miRNA cluster in prostate cancer cells. Oncogene 33, 1448-1457.
21. Catto, J. W., Alcaraz, A., Bjartell, A. S., De, Vere, White, R., Evans, C. P., et al. (2011) MicroRNA in prostate, bladder, and kidney cancer: A systematic review. Eur. Urol. 59, 671-81.
22. Yang, X., Bemis, L., Su, L. J., Gao, D., and, Flaig, T. W., (2012) miR-125b regulation of androgen receptor signaling via modulation of the receptor complex co-repressor NCOR2. Biores. Open Access 1, 55-62.
23. Mo, W., Zhang, J., Li, X., Meng, D., Gao, Y., et al. (2013) Identification of novel AR-targeted microRNAs mediating androgen signalling through critical pathways to regulate cell viability in prostate cancer. PLoS One. 8, e56592.
24. Fletcher, C. E., Dart, D. A., Sita-Lumsden, A., Cheng, H., Rennie, P. S., et al. (2012) Androgen-regulated processing of the oncomir miR-27a, which targets Prohibitin in prostate cancer. Hum. Mol. Genet. 21, 3112-3127.
25. Ishteiwy, R. A., Ward, T. M., Dykxhoorn, D. M., and, Burnstein, K. L., (2012) The microRNA -23b/-27b cluster suppresses the metastatic phenotype of castration-resistant prostate cancer cells. PLoS One. 7, 11e52106.
26. Bonnet, E., Michoel, T., Van de Peer, Y., (2010) Prediction of a gene regulatory network linked to prostate cancer from gene expression, microRNA and clinical data. Bioinformatics. 26, i638-i644.
27. Sun, T., Wang, Q., Balk, S., Brown, M., Lee, G. S., et al. (2009) The role of microRNA-221 and microRNA-222 in androgen-independent prostate cancer cell lines. Cancer Res. 69, 3356-3363.
28. Zheng, C., Yinghao, S., Li, J., (2012) miR-221 expression affects invasion potential of human prostate carcinoma cell lines by targeting DVL2. Med. Oncol. 29, 815-822.
29. Sun, T., Wang, X., He, H. H., Sweeney, C. J., Liu, S. X., et al. (2014) miR-221 promotes the development of androgen independence in prostate cancer cells via downregulation of HECTD2 and RAB1A. Oncogene. 33, 2790-2800.
30. Sun, M., Estrov, Z., Ji, Y., Coombes, K. R., Harris, D. H., et al. (2008) Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells. Mol. Cancer Ther. 7, 464-473.
31. Kojima, K., Fujita, Y., Nozawa, Y., Deguchi, T., and, Ito, M., (2010) miR-34a attenuates paclitaxel-resistance of hormone-refractory prostate cancer PC3 cells through direct and indirect mechanisms. Prostate 70, 1501-1512.
32. Rokhlin, O. W., Scheinker, V. S., Taghiyev, A. F., Bumcrot, D., Glover, R. A., et al. (2008) MicroRNA-34 mediates AR-dependent p53-induced apoptosis in prostate cancer. Cancer Biol. Ther. 7, 1288-1296.
33. Kashat, M., Azzouz, L., Sarkar, S. H., Kong, D., Li, Y., et al. (2012) Inactivation of AR and Notch-1 signaling by miR-34a attenuates prostate cancer aggressiveness. Am. J. Transl. Res. 4, 432-442.
34. Qu, F,., Cui, X., Hong, Y,., Wang, J., Li, Y., et al. (2013) MicroRNA-185 suppresses proliferation, invasion, migration, and tumorigenicity of human prostate cancer cells through targeting androgen receptor. Mol. Cell. Biochem. 377, 121-130.
35. Li, X., Chen, Y. T., Josson, S., Mukhopadhyay, N. K., Kim, J., et al. (2013) MicroRNA-185 and 342 inhibit tumorigenicity and induce apoptosis through blockade of the SREBP metabolic pathway in prostate cancer cells. PLoS One. 8, e70987.
36. Lin, P. C., Chiu, Y. L., Banerjee, S., Park, K., Mosquera, J. M., et al. (2013) Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression. Cancer Res. 173, 1232-1244.
37. Boll, K., Reiche, K., Kasack, K., Mörbt, N., Kretzschmar, A. K., et al. (2013) miR-130a, miR-203 and miR-205 jointly repress key oncogenic pathways and are downregulated in prostate carcinoma. Oncogene. 32, 277-285.
38. Hagman, Z., Haflidadóttir, B. S., Ceder, J. A., Lame, O., Bjartell, A., et al. (2013) miR-205 negatively regulates the androgen receptor and is associated with adverse outcome of prostate cancer patients. Br. J. Cancer 108, 1668-1676.
39. Nadiminty, N., Tummala, R., Lou, W., Zhu, Y., Zhang, J., et al. (2012) MicroRNA let-7c suppresses androgen receptor expression and activity via regulation of Myc expression in prostate cancer cells. J. Biol. Chem., 287, 1527-1537.
40. Ramberg, H., Alshbib, A., Berge, V., Svindland, A., and, Tasken, K. A., (2011) Regulation of PBX3 expression by androgen and Let-7d in prostate cancer. Mol. Cancer. 10, 50.
41. Josson, S., Sung, S. Y., Lao, K., Chung, L. W., and, Johnstone, P. A., (2008) Radiation modulation of microRNA in prostate cancer cell lines. Prostate 68, 1599-1606.
42. Cao, P., Deng, Z., Wan, M., Huang, W., Cramer, S. D., et al. (2010) miRNA-101 negatively regulates Ezh2 and its expression is modulated by androgen receptor and HIF-1α/HIF-1β. Mol. Cancer 9, 108.
43. Gong, A. Y., Eischeid, A. N., Xiao, J., Zhao, J., Chen, D., et al. (2012) miR-17-5p targets the p300/CBP-associated factor and modulates androgen receptor transcriptional activity in cultured prostate cancer cells. BMC Cancer 12, 492.