MiR-221 promotes the development of androgen independence in prostate cancer cells via downregulation of HECTD2 and RAB1A

Oncogene

Volumn 33, Issue 21, 2014, Pages 2790-2800

  Sun, T ^a   Wang, X ^a   He, H H ^a   Sweeney, C J ^a   Liu, S X ^a   Brown, M ^a   Balk, S ^a   Lee, G Sm ^a   Kantoff, P W ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

androgen receptor signaling; castration resistant prostate cancer; MicroRNA; miR 221

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; CYCLIN B1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HECTD2 PROTEIN; MICRORNA 221; MICRORNA 222; PEPTIDES AND PROTEINS; RAB1A PROTEIN; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ANDROGEN THERAPY; ARTICLE; BINDING SITE; CANCER GROWTH; CASTRATION RESISTANT PROSTATE CANCER; CELL CYCLE REGULATION; CELL PROLIFERATION; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; G1 PHASE CELL CYCLE CHECKPOINT; G2 PHASE CELL CYCLE CHECKPOINT; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LNCAP CELL LINE; M PHASE CELL CYCLE CHECKPOINT; MALE; METASTASIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TRANSIENT TRANSFECTION; VECTOR CONTROL;

ANDROGENS; CELL CYCLE; CELL LINE, TUMOR; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MICRORNAS; PHENOTYPE; PROSTATIC NEOPLASMS, CASTRATION-RESISTANT; RAB1 GTP-BINDING PROTEINS; RECEPTORS, ANDROGEN; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSCRIPTOME; UBIQUITIN-PROTEIN LIGASES;

EID: 84901490134     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2013.230     Document Type: Article

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